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  1. Jonathan Edwards

    Concerns about Cochrane

    It seems not. https://jcoynester.wordpress.com/2017/04/13/why-i-am-formally-requesting-the-data-set-from-a-cochrane-review/ gives some idea. Larun is at the Norwegian Institute of Public Health.
  2. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    Yes, that is what I was calling a 'paper'. This to me tells us nothing particularly important. I was responsible for diagnosing and treating heart attacks starting from 1974 as an intern and then as a registrar in A/E for about ten years. The range of symptoms given there was very familiar. The...
  3. Jonathan Edwards

    Concerns about Cochrane

    It says: Bayer actually started the ritual in the early 20th century in order to keep their pills in place. Powder pills would often break from moving around in the bottle and people weren't getting their proper dosage because they would try to piece them together. Medicine has come a long way...
  4. Jonathan Edwards

    Concerns about Cochrane

    Today's episode looked pretty messy too. It seems to have a John Le Carré feel in the sense that the good guys never quite get a chance even when you think they might. But there's two more episodes to go I gather...
  5. Jonathan Edwards

    Concerns about Cochrane

    Perhaps you are a bit modern too, Sasha. I think we called them aspirins because they came in a jar of 500 with cotton wool at the top. It may be that my father had filched them from the pharmacy at work but I think even Boots supplied bottles like that (brown ones) until they started worrying...
  6. Jonathan Edwards

    NICE turns down Valerie Eliot Smith as stakeholder

    Is that because Chinese is written from right to left?
  7. Jonathan Edwards

    Concerns about Cochrane

    I realise we have to treat you Americans with sympathy, since things are going a bit awry in the Senate these days, but the English take aspirins, usually three to make 900mg. We don't take some penicillins or even paracetamols (which I think you refer to as acetaminophen) but these are a bit...
  8. Jonathan Edwards

    Pitfalls In Cytokine Measurements – Plasma TGF-Β1 In Chronic Fatigue Syndrome

    This is a very old story. Essentially it says 'a badly controlled study was done about ten years ago and because the result does not suit us we want to make sure we publish this fact, even if it has taken us ten years to get the paper accepted'. The point that you have to treat test and control...
  9. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    I think what they will do is this. They will say these arguments are pretty similar (which they are): Hysteria is more common in women, so ME is hysteria. Medicine is sexist, so the lack of treatment of ME has been sexist. So the ME advocates are really just the same as the BPS advocates -...
  10. Jonathan Edwards

    Bristol - New Network - Prof Munafo

    I think Munafo has listened. And not shut the door. My impression is that he might have said more but that he also has to gauge what he says in public. A useful exchange.
  11. Jonathan Edwards

    Concerns about Cochrane

    You might want to see a psychotherapist about that. Preferably one not trained in psychology but who makes good home made lemonade and has some aspirins.
  12. Jonathan Edwards

    Concerns about Cochrane

    Sometimes google translate seems to preserve the poetry!
  13. Jonathan Edwards

    LP coach on research, Lightning Process and ME (Norway)

    The problem is that they do not actually know what they mean by these words. They think the words must mean something and when they all say them together they convince each other of it, but they don't. Stupid people will go on behaving like this forever. And as we can see from the election of...
  14. Jonathan Edwards

    UK CMRC 2018 Conference held September 19 & 20 at Bristol

    £20 million is always available from MRC for ME but it only makes sense for them to offer it to someone if they can show they have a good idea to work on. If £20million was offered to anyone who came along we would immediately have someone snapping it up who had no idea what they are doing - we...
  15. Jonathan Edwards

    Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation (2018) Albrecht et al.

    Interesting. It looks a well planned study at first glance. The data are plausible and would be very significant if confirmed.
  16. Jonathan Edwards

    Trying Again. What First? D-Ribose? BCAA's?

    It is pretty easy because it is really quite hard to be short of basic requirements. If someone is short of vitamin C then to my mind the answer is to eat some fruit. You are obviously at liberty to do whatever you like but the idea that supplements are needed at all is as far as I know almost...
  17. Jonathan Edwards

    Concerns about Cochrane

    I think they are quite specifically failing to be specific and yes it is far worse. The only good thing I see hear is that their handling of the situation is so bad they will lose all credibility. Cochrane is busted I think.
  18. Jonathan Edwards

    Berkeley Wellness: When Medical Symptoms Are Dismissed as "All in Your Head" (David Tuller interviews Maya Dusenbery)

    Is there any reason to think that? Much of the time there seems to be no obvious reason to make a distinction but where there is a reason it is usually done. Risk estimates in cardiovascular disease take into account sex difference in all sorts of ways. I think it is pretty unusual to have an...
  19. Jonathan Edwards

    Concerns about Cochrane

    Maybe he cracks his finger joints during committees? It's laughable. Maybe the opposite of dis-rupt is co-rrupt?
  20. Jonathan Edwards

    Bristol - New Network - Prof Munafo

    Very nicely made point. To be frank his answer is wimpish and disingenuous. If he wants to change research culture he needs to get out there with a placard and get very mired in those debates. Edit: I see things have moved on. I am sure Graham and Sasha will find the perfect compromise without...
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