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I could not see any link to a manifesto? Do you mean the BRCT website or Munafo's network? So far I id not think Munafo was linked to BRTC.

The more I see of this the more it looks as if this is all part of a deliberate policy. The blurb talks of 'high quality pragmatic randomised controlled trials' but there is no such thing. A pragmatic trial is something quite different from a standard RCT. What they mean by pragmatic here is...

Nice idea Graham but I agree you need to tell him the punch line at the start. Something like: I am pleased to see you are setting up an organisation for 'co-ordinating shared training and best practice across research-intensive universities' but are you aware that your own BRTC at Bristol is...

Not at all. All these things tell us something useful about other people's perceptions. I noted, on the topic of freeze that someone at the CMRC meeting is talking of total body cryotherapy or something. It will be interesting to know what that is about.

Sort of great-grandma-traumababble?

My impression is that the main players still thought they were untouchable until about November 2017. Up until that point Cawley was giving lectures on how to evade awkward questions about your research -presumably thinking she was succeeding.

I think the 'loophole' will be the attitude of a chairman of a surveillance committee. Backed up by the attitude of one or more journal editors.

Anti-muscarinic antibodies are notorious for being pretty meaningless, with regular false positives. The differences between ME and controls for these antibodies do not at all suggest that they are relevant to symptoms directly. If they were one would expect a much more black and white difference.

The irony is that an organisation that includes people who are prepared to, and allowed to, criticise the output of said organisation in public is exactly the sort of organisation that gathers trust. The expulsion is a PR disaster in exactly the terms they seem to have been trying to promote...

A very sane and perspicacious nutcase I think. Certainly not someone to expel from your board if already on it. At least he is up front about his position.

Yup. It isn't a legal issue anyway, it is a moral one.

They say bugger all, except that Gotzsche was 'behaving badly'. The key bit seems to me to be: All our staff, and our members, have the right to do their work without harassment and personal attacks. Sounds familiar. Any criticism of standard of science is a personal attack it seems these...

It is about a long-term pattern of behaviour that we say is totally, and utterly, at variance with the principles and governance of the Cochrane Collaboration. This is about integrity, accountability and leadership. Yes, well, being critical is a pattern of behaviour that tends to go with...

From the planet zog, I suspect. She must like the way things are.

According to Wikipedia not this.

I actually think that statisticians should be expected to know, and in that regard I agree with @Lucibee. I should be expected to know enough about stats to judge whether a statistician is giving properly informed advice. I have to know enough about the other person's subject to make sure thing...

It is a statistician's job to be aware of the concept of bias and its dynamics but I don't think it is their job to know the realities of how bias arises in specific situations - because that is the job of the scientists doing the experiment. Having said that one can reasonably expect...

Mm. I don't think this usage of right and duty has to do with legal constructs. I think it is an older ethical idea, is it not? Those who have power or resources have an ethical obligation to use them well. That turns up in rules of accountability within organisations but I don't think it is a...

I have been trying to work out what he meant (Einstein). Presumably he meant that you must share all your results. Coming from Sharpe that is serious irony.

I agree these are key questions. The problem is that people trained in statistics have no particular reason to understand the more basic problems of trial design that arise from sources of bias - human nature. You cannot use numbers to assess the likelihood of bias. The jobs you want done are...