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  1. Sean

    SMILE trial data to be released

    :):):):):):):):):):):):):):):):):):):):):):):)
  2. Sean

    Trial By Error: Kaiser Permanente Changes Course

    Webdog for Prez! Oh say can you see by the dawn's early light, our furry little friend with the great big sharp bite! :thumbup: :thumbup: :thumbup: :hug: –––––––– "How did we remain ignorant for so long?" Whatever the final explanation for that is, it will gave to include the word...
  3. Sean

    Who said: don't bother testing patients?

    Anybody still doubt that Wessely has been a brutally effective smear merchant from the very start?
  4. Sean

    Cochrane ME/CFS GET review temporarily withdrawn

    I think what this shows most of all is just how ill-prepared Cochrane are for dealing with this kind of problem, and that they urgently need to develop more robust and timely means of doing so. The rule (?) that they cannot withdraw a paper without the author's consent is particularly...
  5. Sean

    Blog: The real reason I’ve stopped writing for The Canary? Watch this video. by Steve Topple

    Can't remember who said it (Oliver Sacks?), but it goes something like: The most important question in medicine is how to respond to those patients you can't offer any effective treatment. An interesting thought for our times.
  6. Sean

    Journal of Medical Ethics - Blog: It’s Time to Pay Attention to “Chronic Fatigue Syndrome” (2019) O'Leary

    Direction of causality is what distinguishes between psychosomatic and biomedical.
  7. Sean

    Journal of Medical Ethics - Blog: It’s Time to Pay Attention to “Chronic Fatigue Syndrome” (2019) O'Leary

    Agree with this. One of the more disturbing aspects of all this whole farce is how much is hand waved away and swept under carpets by those insisting that the physical-mental divide doesn't exist, is an old outdated view, unproductive, misleading, unimportant,... whatever. But direction of...
  8. Sean

    what are you using for toothpaste?

    :thumbup: I brush and rinse, then put a fresh dab of toothpaste in my mouth and spread it on the teeth, and leave it there.
  9. Sean

    Personality and fatal diseases: Revisiting a scientific scandal, 2019, Pelosi

    They crossed over into a cult a while back, IMHO.
  10. Sean

    Psychology & Health: Perfectionism and beliefs about emotions in adolescents with chronic fatigue syndrome and their parents (2019) Chalder et al.

    The level of mediocrity required to produce such drivel is mind boggling. And that is the generous interpretation. :D
  11. Sean

    Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients (2019) Tomas, Brown, Newton, Elson

    measured using extracellular flux analysis. I have often wondered if the extracellular matrix is somehow involved, particularly the amorphous component.
  12. Sean

    Wessely and double-blinding

    Posting this from Wessely in a 2009 interview, because it shows that he clearly understands the importance of double-blinding subjective outcome measures and controlling for the placebo effect, and is happy to (selectively) invoke this standard when it suits him to further his psychosocial...
  13. Sean

    Royal College of Surgeons blog: Are surgeons missing the major differential diagnosis that is more common than multiple sclerosis and HIV combined?

    That is the get-out-of-jail-free card for them. Just classify uncooperative patients as being of unsound mind, and it all becomes so much easier for doctors and policy makers.
  14. Sean

    Long Term Follow up of Young People With Chronic Fatigue Syndrome Attending a Pediatric Outpatient Service, 2019, Rowe

    Well, either the situation with juveniles is something like Jonathan Edwards described (at comment #10), a distinct possiblility. Or a number of different disorders are being mixed in. Or a bit of both. Diagnostic rigour remains a serious concern here.
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