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This I can believe. Presumably these kids had endured a year of being told their thinking is all wrong. So the shift to being told that 'yes, you really do have a problem that's difficult to live with' must have been a relief. I agree wholeheartedly with all the criticism posted here but I have...

Especially given the increasing and often very loose use of the term PEM outside ME. I agree with your point but I'm struggling with getting my head around the chicken and egg situation. We know that there's a roughly 50/50 chance of people diagnosed with ME or CFS not actually having it as...

That's actually a technical term, I just looked it up thinking it must be a typo :rofl: Is this the longest ME hypothesis paper ever published? Especially since it looks to be only one half of the full hypothesis. Anyway, the biochemistry is way above my head, so no idea how much sense it...

Even if it's not specific to ME I wonder if repeated HGS testing could be developed to be sufficiently sensitive to function as an objective outcome measure in treatment studies? For the same reason the quadriceps testing they did is interesting. I'd never heard of it but looking at the...

Not in New Zealand. This is the current list of conditions considered a priority for vaccination. Can't see ME making the list even if it does get reviewed. I just hope we can keep the virus out of the country until we're all vaccinated anyway. Sadly not even a possibility for most countries...

This study neatly demonstrates the pitfalls of using Fukuda. 1) We have a cohort selected by Fukuda which is likely to consist of 2 groups, one which experiences PEM and another which does not (but this paper doesn't report this detail). 2) We have an exercice programme where a large number...

Agree with your comments re the questionnaire. Sad thing is it's one of the better ones out there, at least for guiding a clinical interview where a questionnaire is just the start of the process. My guess is that's how it started life, as a clinical tool. And the researchers probably did talk...

I read somewhere that this fear is supposedly unfounded because the type of blood clots associated with the contraceptive hormones are the "normal" blood clots whereas the ones possibly associated with the vaccines are a much rarer and different type. It was some sort of medical expert...

I never get swollen glands, they're not even palpable. However, they do get rather sore occasionally, chin, neck and armpits. Happens on both sides, haven't noticed any difference re left or right. Pretty sure not related to PEM but possibly to periods of being generally worse though haven't...

Lots of confusing data here. A surprisingly large number - given that virtually everybody met PEM-obligatory criteria - don't report PEM after physical exertion: The figure of 58.2% seems to conflict with Table 3 which shows medium level activity as a trigger for 71.5% but high level physical...

Cort has done a blog on this study but that's still the closest I've come to the actual paper, beyond the abstract. Has anyone been able to access the full paper yet? https://www.healthrising.org/blog/2021/03/30/muscle-fibromyalgia-chronic-fatigue-syndrome/

I think 'functional' in this context just refers to the images you get from fMRI. I've only a vague notion of what fMRIs show but broadly speaking they show brain activity(=function) as opposed to (or in addition to?) brain structure. 'Functional' is one of those words that are perfectly fine...

Haven't read the paper, only looked at the graphs, one of which showed the results of a "trail making test". No idea what that was so looked it up. Wikipedia says: https://en.wikipedia.org/wiki/Trail_Making_Test The highly educated Covid cohort in this study did particularly badly at the...

Did she say what exactly the modest rise in body temp does that is beneficial? Pre-diagnosis when I was still foolish enough to go for short walks in an attempt to improve my ever diminishing fitness I came home after one such walk on a warm day but feeling cold to the bone so took my...

Your real problem is that you're trying to not fall out of a tree in your sleep :emoji_evergreen_tree::zzz:o_O Wikipedia says so, so it must be true. Plus I like that explanation better than the usual - equally unproven - suspects of anxiety and stress. https://en.wikipedia.org/wiki/Hypnic_jerk...

Re the blood clot/bleeding issues with the AZ vaccine, in Denmark the hypothesis of poor vaccination technique as a possible cause seems to be taking hold. Basically, poor vaccination technique can on very rare occasions lead to people getting the vaccine into their bloodstream and that's a...

Chicken and egg I guess. You can't monitor large numbers of people to see what's normal until you have a device to monitor them with. And until you've monitored them you can't tell if your device shows normal or otherwise. :confused:

Shorter press release about the study (which is TL;DR). "New Skin Patch Brings Us Closer to Wearable, All-In-One Health Monitor Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and...

Prototype. "Monitoring the effects of daily activities on the physiological responses of the body calls for wearable devices that can simultaneously track metabolic and haemodynamic parameters. Here we describe a non-invasive skin-worn device for the simultaneous monitoring of blood pressure...

The main thrust of the paper (have only read the abstract) seems to be about the perceivers' judgements. I wonder why they didn't go digital instead of using actual patients and trying to do the impossible, i.e. somehow measure and match "true" levels of pain and facial expressiveness? Start...