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News in brief for w/c 18th posts https://www.facebook.com/sci4me/posts/pfbid0YqwuK9qx1TfUs5u7wgUUh739SfARcay46jduUFR746NEscLFpdZeaj6GzR3rtVM9l And published papers thread https://www.facebook.com/sci4me/posts/pfbid0tG84EJK1CAj61Cp3fdBzFTytNeytMH3dfmQVQcBCJXD6Kztdm27wiJWNr876Sb3yl

Abstract Clinically used inhibitors of mammalian target of rapamycin (mTOR) negatively impacts endothelial-dependent vasodilatation (EDD) through unidentified mechanisms. Here we show that either the endothelium-specific deletion of Mtor to inhibit both mTOR complexes, or depletion of Raptor or...

Abstract Coronavirus disease 2019 is known to impact older people more severely and to cause persistent symptoms during the recovery phase, including cognitive and neurologic ones. We investigated the cognitive and neurologic features of 100 elderly patients with confirmed diagnosis of...

Abstract The EuroQol 5-dimensions 5-levels (EQ-5D-5L) is a generic patient-reported outcome measures (PROM) used for evaluating health-related quality of life (HRQoL). No data on its psychometric properties in COVID-19 survivors is available. We aimed to describe internal consistency...

HIGHLIGHTS •We hypothesized that a supplementation combining L-Arginine (to improve endothelial function) and Vitamin C (to reduce oxidation) could have beneficial effects in Long-COVID. •We designed a nationwide multicenter clinical study, in which we administered to COVID-19 survivors a...

Abstract Background Athletic underperformance is characterized by fatigue and an inability to sustain a consistent exercise workload. We describe five elite swimmers with prolonged fatigue and athletic underperformance. Based on our work in myalgic encephalomyelitis /chronic fatigue syndrome...

Abstract Background Cognitive behavioral therapy (CBT) is an evidence-based intervention for severe fatigue. Changes in patients’ fatigue scores following CBT might reflect not only the intended relief in fatigue but also response shift, a change in the meaning of patients’ self-evaluation...

A blog, the second part of which covers this preprint. Peroxisomes, Mitochondria, And Fibrinoid Microclots: Two New Preprints. https://www.meprecisely.com/2022/07/19/peroxisomes-mitochondria-and-fibrinoid-microclots-two-new-preprints/

A blog looking at, in part, this study. Peroxisomes, Mitochondria, And Fibrinoid Microclots: Two New Preprints. https://www.meprecisely.com/2022/07/19/peroxisomes-mitochondria-and-fibrinoid-microclots-two-new-preprints/

Abstract The bio-psycho-social model highlights intra-individual and inter-individual interactions, including psychotherapy. The processing of these interactions within a person takes place, among others, in the central autonomic network (CAN). The CAN's autonomic output to the periphery can be...

And tweet from ME Research UK

For me this highlights the dangers of clinicians and researchers being viewed as experts on ME, or any other conditions, when the experience of patients that they have are of the ones that go to their clinics and labs i.e. typically those that are less severely affected. They may well be talking...

Surveillance of diseases is a standard part of the work that CDC does so, taking it at face value, the fact that they will start doing that with ME is a step forward for us. https://www.cdc.gov/surveillance/index.html

Ah, OK. thanks for the explanation. I'll redo it then. ETA: Now done, new tweet in my post above.

Abstract Background FND is a disabling disease that accounts for 5 to 10% of the reason for consultation in neurology. However, young physicians often say they have little or no training in their management. Aim The aim of the present study was to assess whether French junior neurologists...

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV) represent two highly transmissible airborne pathogens with pandemic capabilities. Although these viruses belong to separate virus families—SARS-CoV-2 is a member of the family Coronaviridae, while...

Full title: Developing a long covid phenotype for post-acute COVID-19 in a national primary care sentinel cohort: an observational retrospective database analysis ABSTRACT Background: Following COVID-19 up to 40% of people have ongoing health problems, referred to as “post-acute COVID-19” or...

The paper that the news release is based on. Global seroprevalence and sociodemographic characteristics of Borrelia burgdorferi sensu lato in human populations: a systematic review and meta-analysis Abstract Introduction Borrelia burgdorferi sensu lato (Bb) infection, the most frequent...

"ME Research UK currently has an open call for applications for our research grants, and we welcome proposals from researchers wishing to investigate the causes, consequences and treatment of ME/CFS. The deadline for submissions for this call is 5 p.m. BST on Friday 16 September 2022."...

I would put forward an argument that whether or not someone feels shame can depend on how reliant they are on the opinions of others, which would often correlate to how old they are. So children and young adults are far more vulnerable to take the word of so-called experts at face value, and...