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  1. Andy

    Closed UK: DecodeME updates, was recruitment thread.

    We sent out our first reminder email today. This went to those who are on our contact list who, best we can tell, have not yet signed up to take part in the study.
  2. Andy

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    Prof Kell on Twitter, "To those doing well on nattokinase and/or serrapeptase and/or lumbricase pls can you tell #TeamClots which BRAND and frequencies you use. Just poss that some non-responders are using lousy brands. Can then at least then use those known to work."
  3. Andy

    Mitochondrial oxidative stress contributes to diastolic dysfunction through impaired mitochondrial dynamics 2022 Lozhkin et al

    Highlights • Transgenic mice with mitochondria-targeted NOX4 overexpression develop diastolic dysfunction. • Nox4TG mice with diastolic dysfunction have impaired mitochondrial dynamics and function. • Ιncreased inflammatory cytokine levels and myocardial interstitial fibrosis underlie...
  4. Andy

    International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia, 2022, Kundakci et al

    Highlights • Although non-pharmacological interventions are recommended as first-line treatment for fibromyalgia, there are currently no evidence-based recommendations as to which intervention(s) to offer as core and adjunctive treatments for each common symptom in fibromyalgia. • This Delphi...
  5. Andy

    Psychogenic non-epileptic seizures (PNES) in the COVID-19 pandemic era: A systematic review with individual patients' analysis 2022 Done et al

    Abstract Objective Psychogenic non-epileptic seizures (PNES) resemble epileptic seizures but are not due to underlying epileptic activity and in some cases coexist alongside epilepsy. We described the clinical characteristics of patients with PNES as reported in the literature from the outbreak...
  6. Andy

    Fatigue in Covid-19 survivors: The potential impact of a nutritional supplement on muscle strength and function 2022 Galluzzo et al

    Highlights Assessment of muscle function in persons recovered from COVID-19 is often neglected. Nutritional supplementation may enforce muscle strenght and function in COVID-19 survivors affected by fatigue. Daily assumption of magnesium, zinc, arginine and carnitine can improve physical...
  7. Andy

    International: Science for ME social media posts

    And September's News in Brief posts on Reddit
  8. Andy

    International: Science for ME social media posts

    News in Brief posts for w/c 26th September https://www.facebook.com/sci4me/posts/pfbid0KmJb1BQe4mEbp1iHkBWytuyHPkgSPo3CiiyJALMcojxFJFiLmNHHYp7VtUsBMvY6l and published papers thread. https://www.facebook.com/sci4me/posts/pfbid0NxxjCx6c8q2WJJwFB1eSpx53mzmniuQu2vQC5hehkaL3t3hrXgJwyJGrEeyTR1exl
  9. Andy

    Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): Protocol for a Randomized Controlled Trial, 2022, Busse et al

    Well, given that Garner is prone to staring down barrels of guns, so I'm not sure that he is prone to thinking things through.
  10. Andy

    Predictors of Male Sexual Dysfunction in Urologic Chronic Pelvic Pain Syndrome (UCPPS), Other Chronic Pain Syndromes, 2022 Loh-Doyle et al

    Full title: Predictors of Male Sexual Dysfunction in Urologic Chronic Pelvic Pain Syndrome (UCPPS), Other Chronic Pain Syndromes, and Healthy Controls in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Abstract Background Sexual dysfunction (SD)...
  11. Andy

    Protracted stress-induced hypocortisolemia may account for the clinical and immune manifestations of Long COVID 2022 Yavropoulou et al

    Abstract About one out of eight people to convalesce from COVID-19 suffer from the so called Long COVID, a syndrome of non-specific symptoms with unclear pathogenesis. In a recent study published in Cell Long COVID participants reporting respiratory symptoms had low cortisol levels. In an as...
  12. Andy

    COMET initiative: Core Outcome Set for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

    From the homepage, https://www.comet-initiative.org/ "A core outcome set (COS) is an agreed standardised set of outcomes that should be measured and reported, as a minimum, in all clinical trials in specific areas of health or health care." which obviously could be a sensible and useful list...
  13. Andy

    Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): Protocol for a Randomized Controlled Trial, 2022, Busse et al

    Importance: Chronic, non-cancer pain affects approximately 20-30% of the population in North America, Europe, and Australia, with surgery and trauma frequently cited as inciting events. Prospective studies of fracture patients have demonstrated an association between somatic pre-occupation, poor...
  14. Andy

    ‘The Lightning Process’ and chronic fatigue syndrome/myalgic encephalomyelitis, 2022, Vallings

    Yeah, I thought her condemnation was pretty weak. Also frustrating to see her use CFS/ME.
  15. Andy

    ‘The Lightning Process’ and chronic fatigue syndrome/myalgic encephalomyelitis, 2022, Vallings

    As Medical Advisor to the NZ ME Association (ANZMES) and having worked in this area of medicine for 40 years, I am concerned that recent GP educational events have promoted ‘The Lightning Process’,1,2 predominantly used for treatment of chronic fatigue syndrome/myalgic encephalomyelitis...
  16. Andy

    COMET initiative: Core Outcome Set for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

    Thought I recognised Jason Busse from somewhere BMJ: Rapid response to 'Updated NICE guidance on CFS', 2021, Jason Busse et al, Co-chair and members of the GRADE working group and here it is reported they were recruiting for this on Reddit, News from Canada
  17. Andy

    COMET initiative: Core Outcome Set for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

    Spotted the above following @Caroline Struthers tweeting about
  18. Andy

    COMET initiative: Core Outcome Set for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

    Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) a long-term, complex, debilitating disorder associated with poor health-related quality of life and declined functional status for individuals and a significant economic burden on society. CFS/ME is defined by symptoms and patient’s...
  19. Andy

    Crowdfunding: Trial By Error [David Tuller]: Reporting on ME, ME/CFS, long Covid, and "Medically Unexplained Symptoms", Oct 2022

    A combination of the energy crisis and, specifically to the UK, a weaker pound will make hitting the target this time a challenge, although hopefully Long Covid folks can see that funding Dave is an investment.
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