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Highlights Patients with Functional Neurological Disorder experience stigma from many sources. Work, family and online interactions contribute to stigma. FND is often perceived as something unknown, fuelling experiences of being “othered”. Self-stigma and anticipated stigma are common...

I don't see if they explain how what criteria they use to select participants.

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe condition with an uncertain origin and a dismal prognosis. There is presently no precise diagnostic test for ME/CFS, and the diagnosis is determined primarily by the presence of certain symptoms. The current study...

Trial By Error: Australian GP Group Recommends “Incremental Physical Activity” for “CFS/ME” Patients https://virology.ws/2024/04/25/trial-by-error-australian-gp-group-recommends-incremental-physical-activity-for-cfs-me-patients/

Self-reported coronavirus (COVID-19) infections and associated symptoms, England and Scotland: November 2023 to March 2024 Main points An estimated 3.3% (2 million) of people living in private households in England and Scotland were experiencing self-reported long COVID (symptoms continuing...

Full title: Hepatitis B virus and hepatitis C virus affect mitochondrial function through different metabolic pathways, explaining virus-specific clinical features of chronic hepatitis Abstract Background Hepatitis C virus (HCV) and hepatitis B virus (HBV) cause chronic hepatitis with...

Abstract Aim To investigate the clinical characteristics of non-epileptic seizures due to transient brain dysfunction caused by energy deficiency after prolonged fasting or exercise in individuals with glucose transporter type 1 deficiency syndrome (Glut1DS), and then elucidate further the...

Abstract Up to 25% of patients recovering from antibiotic-treated Clostridioides difficile infection (CDI) develop functional symptoms reminiscent of Post-Infectious Irritable Bowel Syndrome (PI-IBS). For patients with persistent symptoms following infection, a clinical dilemma arises as to...

So without a significant impact on quality of life, exercise doesn't seem to be an effective medicine for this patient group.

Abstract Background Diminished muscle protein synthesis in cirrhosis leads to reduced strength and mass, impacting daily activities and overall quality of life. Aims This study aimed to examine the effectiveness of exercise intervention in body composition, exercise capacity, fatigue, and...

Yep, my functional level is even lower and the demands on my time are even higher.

All major ME/CFS criteria include immediate exacerbation of symptoms in their descriptions of PEM - that is the most serious problem.

Todd Davenport, of the Workwell Foundation, was asked if the 2xCPET measured PEM or the associated energy loss. The start of his answer is "Thanks for this interesting question and set of observations. I appreciate you sharing them, as I also appreciate the chance to share. In the first part...

"Funding This study is funded by the NIHR Health Services and Delivery Research programme (project: 15/136/07)." Googling that project reference leads me to the Multiple Symptoms Study 3 page on the Uni of Sheffield website, https://www.sheffield.ac.uk/ctru/current-trials/mss3, and reminded me...

"Influenza is the pathogen most likely to trigger a new pandemic in the near future, according to leading scientists. An international survey, to be published next weekend, will reveal that 57% of senior disease experts now think that a strain of flu virus will be the cause of the next global...

USDA Confirms Cow-to-Cow Transmission a Factor in Avian Flu Spread "The U.S. Department of Agriculture said this week that cow-to-cow transmission is a factor in the spread of avian flu in dairy herds, but it still does not know exactly how the virus is being moved around. Farmers and...

For clarity, I doubt that viral persistence is the issue for folks with Long Covid, or for that matter ME/CFS. However, I would be happy to change my mind if presented with a decent evidence base to support it. But I am all for patient groups forcing policy makers to abandon hypotheses that...

"Friday 19th April 2024 marked the inaugural meeting of the PANS PANDAS Clinical Guidelines Development Group, held in central London. With 30 attendees, including clinicians from all relevant fields of medicine and representatives from the patient community, the formation of this group...

Three likes, four re-posts.

Published papers thread for w/c 15th April. Facebook: https://www.facebook.com/sci4me/posts/pfbid02zGkW2E1kNnAxvR6a21cdPyvcHRoXwmztk76rbahvcDe6meJHA3FtxpcYv5EUnkTfl Mastodon: https://med-mastodon.com/@s4me/112314128676593530