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Pre morning coffee - so this may be totally tangential - apologies in advance. As body senses CO2 and not oxygen, perhaps it is more of a CO2 / O2 balance issue? Would switch to anaerobic metabolism impact?

In a normal person, someone with a simple condition, yes. But i think , give this condition affects all systems, feedback loops may be " wired" differently to maintain function.

That one would also be an interesting one for male/female proportions

Would it have any link to issue with blood volume affecting oxygen levels?

Both authoref by Crawley

Given you are now a trustee(?), have been more severely affected previously, straddle the patient/ organisational divide , it seems strange that you were not aware of this . Had you at least the opportunity to comment on the info pre issue? If not then you may have a significantly bigger...

Adjuvent effect ? May be particularly important for vaccines which provide longer term protection and have a higher load - tetanus / HPV etc Status of female immune system function in childhood/ adolescence? Do we simply assume that it' s only in pregnancy that it modifies? ( Apologies in...

Thinking from the metabolic trap idea that other genes in the same function group may not compensate for mutations in others as has previously been assumed- what common genes linked to liver function might this apply to - high incidence, low penetration and substrate limiting? Would these...

Thanks @Trish . I really need to do some basic tech techniques!

Given the nuances with language deployed by PACE team, and their carefulness to be economic with the truth but not lie, I could believe they didn' t see their data prior to changing outcomes. They didn' t need to. FINE data was available and would have flagged up issues. They could not afford...

@Suffolkres Brilliant resource. Easy to read, graphics give " at a glance" info I think every practice should have a copy.

Apologies if already posted elsewhere. I couldn' t rip the video at the end of this thread. Gordon Broderick succinctly in layman' s terms explaining Klimas' research and highlighting phenylalanine...

Really?

How could anyone forget coffee? :)

Knowing other mums who have been threatened with / through such processes, thank you @Tilly for all you do. Linking to another topic re male/ female differences in advocacy this is a strange area in that FII seems to be targeted at females . Must be those hysterical tendencies, but perhaps...

Thanks @Tilly I suspected a tranche of papers starting at end of last year onwards to retain and reinforce narrative/ control/ reputations. These need to be dissected and appropriately critiqued by science and charities Where are @Action for M.E. and MEA @Russell Fleming and ME Action @EspeMor...

IAPT ...££££

How can it support a hypothesis for CFS when the study was on Hep C patients ?

Perhaps he should be commanding the great ship Brexit too ....

It took nearly 12 months for my aunt to get a home visit. The GP told her that there was nothing she could do and had to be pushed to agree to blood testing . Even with a practice copy of purple book, no sleep/ pain meds offered, no symptom discussion to screen for comorbidities. If there is no...