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1) Much less power/speed, slightly less endurance; 2) Less pain, less PEM for apparently more effort; 3) Only comparing against daily living, as unable to walk or cycle well enough to measure. No knowledge of physiology, but: 1) Prone/supine position during effort may have small effect; 2)...

That sounds like a really important step forward, @Binkie4 – it must be quite hard enough to live with these conditions, without the added insult of medics writing you off as 'just' overweight. :mad:

Bafflingly fleeting enlargement, too; my neck glands will swell up until for as little as an hour, before subsiding again. A gift of Christmas mince pies last month reminded me that I can often trigger the swelling simply by eating sweet foods. Am not keeping up with posts very well because my...

It may not be written for the paper – he has a column, but he's not a full-time staffer. Though it would be good to get a well-written Guardian piece focusing on this issue for once! If he gets it right, it supports and informs Covid patients and throws a bit more public shade on those who've...

It's bound to get sticky at times, when the de facto leader of an organisation has about as deep a personal interest in its mission as it's possible to have. Of course, no-one would criticise Ron Davis for being utterly driven to do the best he can for his son. Any parent would be. But it can...

So far, I haven't had any problems getting slots at Tesco, even though I'm not on the priority list. Fingers crossed! I have a delivery about every fortnight, and try to make sure that I book each one about three weeks ahead. I just add my saved shopping list to the basket to reserve the slot...

Thanks for this, @JemPD. It's also good where possible to buy from reputable suppliers rather than sources such as eBay or Amazon, where it's hard to differentiate between people selling genuine and knockoff products. Just in case people aren't aware, there are medical supplies companies in...

If it's true that up to 10% of people face a long or very long recovery from Covid-19, the fact that the UK is heading rapidly towards reporting 60,000 new cases per day is terrifying. And that's only people who're symptomatic, or have enough reason to think they've been exposed that they come...

Very true. We have to remember that, however prominent Ron and Janet are in their respective fields, the family still struggles to afford care. Whitney hasn't been able to contribute to pensions and build savings during what should have been some of the most productive earning years of his life...

Sort of! I've never known mental exertion cause physical symptoms, but sometimes physical exertion can cause even more profound mental PEM than it does physical PEM.

Pathogens Hijack Host Cell Metabolism: Intracellular Infection as a Driver of the Warburg Effect in Cancer and Other Chronic Inflammatory Conditions Amy D. Proal and Michael B. VanElzakker, 2021 This hypothesis piece discusses metabolic shift in a broad range of chronic conditions, but as it...

...millions of unconnected people who have nothing to gain, but everything to lose. Never mind. Poor dear's only trying to aggravate people because he knows he's history. Discredited history, at that.

"Current indications show that dietary modifications may vastly improve the patients’ quality of life at a low cost." Stopped reading at that point! :bored:

So going back to the nickel allergy – I've just been pondering in the shower about what I'd do if I suspected nickel had got inside my washing up gloves and possibly triggered an allergic reaction. I can tolerate surgical tape on my skin for a while, so what I'd do is cut two small pieces of...

Oh, I only suggested it because many people have a jar of coconut oil in the cupboard anyway – I use it for frying my garlic, ginger and onions for curries. It's not expensive and keeps for ages.

Absolutely. We've had researchers looking into mind-numbingly complex and sometimes poorly understood aspects of biology; this group has recorded and observed the things that they can record and observe with the simplest of tools. Even though there are obvious problems around objectivity, this...

Definitely worth a word with your GP, @Daisybell, if simple things like good hydration and gentle rubbing don't work. Sometimes cramps are a side effect of medication, and the doctor would know whether you take anything that could be the culprit. There might also be treatments that could help.

You'll get there eventually. It does often take a long time, especially if there's more than one factor. My first discovery was that I have lanolin sensitivity, which meant the creams I was prescribed to alleviate the symptoms were making them much worse. Luckily I worked out that petroleum...

As well as the issues about transportation and storage, the Oxford/Astra Zeneca group made a commitment to supply it on a non-profit basis to low- and middle-income countries. This will no doubt help to keeps the costs down. I seem to recall that they're planning to use the large vaccine...

I've had nickel allergy since I was a kid, and it showed up as confirmed on a set of NHS allergy tests I had a few years ago. I've never suspected dietary nickel had any influence, though...it doesn't sound very plausible. Nickel is ubiquitous, and it's probably more likely you came into...