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  1. J

    Cyclophosphamide

    @TrixieStix I think for cyclo, total dosage for auto-immune diseases can exceed those used for cancer, especially, if they have to retreat over a long time period. The dosages used by Fluge/Mella are similar to those used for the treatment of breast cancer, for example...
  2. J

    Cyclophosphamide

    @Jonathan Edwards Thank you for clarifying the 40% number. But I also want to point out that some (at least one person) had a long lasting effect ~4 years from the initial infusion series. So it is possible for people to get long-term remission from one series. Do you still think that...
  3. J

    Cyclophosphamide

    Dear Dr. Edwards, You are correct about the blinding (you had brought this up before, but I forgot--must be the brain fog). But the 40% bladder cancer number is overstated. See here https://onlinelibrary.wiley.com/doi/full/10.1002/art.25061 There is a bladder cancer risk for high dose daily...
  4. J

    Cyclophosphamide

    Hopefully, the Fluge/Mella cyclophosphamide trial results will be published shortly. https://clinicaltrials.gov/ct2/show/NCT02444091 (CYCLOME). This was a phase 2 unblinded study. Jumping the gun a bit, what if the trial is positive, that is there was a response in the patients (let's say...
  5. J

    Ampligen for ME/CFS

    And do we know of any physicians/clinics in Argentina that are administering Ampligen?
  6. J

    Will Barbers Regain Their Role as Medical Practitioners?

    https://www.medpagetoday.com/blogs/revolutionandrevelation/76863?xid=nl_mpt_blog2018-12-12&eun=g1139006d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Packer_121218&utm_term=Packer%20Blog%20-%20Cardio%20list Interesting...if only I had a good barber....
  7. J

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    My ESR was almost 0 at onset (maybe it was zero/undetectable), but has been more or less normal since then. The low ESR was how I (not the physicians) figured out I had this shit thing.
  8. J

    Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018)

    It would be nice to know if Fluge and Mella measured something like this in the CYCLOME study...to see if cyclophosphamide made the blood nice in the patients who were responders...
  9. J

    New sleeping sickness drug approved

    https://www.nytimes.com/2018/11/16/health/sleeping-sickness-africa-cure.html They managed to secure $63 million in funding for this...a horrific disease, but a disease that only affects a couple of thousand people per year.........maybe suramin won't be needed anymore...
  10. J

    A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

    https://www.nature.com/articles/s41467-018-04376-5 Wonder if PWCFS/ME have a Nlrp3 inflammasome signature and IL-1β expression in brain and cerebrospinal fluid, similar to MS Microglia, the mononuclear phagocytes of the central nervous system (CNS), are important for the maintenance of CNS...
  11. J

    NSAIDS (Nonsteroidal Anti-Inflammatory Drugs), e.g. Ibuprofen, Aspirin

    This thread https://www.s4me.info/threads/etoricoxib-arcoxia-any-experiences.5377/
  12. J

    Ampligen for ME/CFS

    What's the update on Ampligen? Are people getting Ampligen in Nevada and North Carolina? How does one get Ampligen in Nevada or North Carolina? Is it working? Can a person get Ampligen in Argentina or Europe? Thanks
  13. J

    CFS Research Center at Stanford Second Annual Community Symposium Sept. 29-2018

    Hi, I missed the symposium--I guessed that there was nothing definitive on Cyclophosphamide from Fluge? I see from Cort Johnson's tweets that he infers that there are some positive results..... Thanks
  14. J

    He Got Schizophrenia. He Got Cancer. And Then He Got Cured.

    From the above article....... “In the late 19th century, physicians noticed that when infections tore through psychiatric wards, the resulting fevers seemed to cause an improvement in some mentally ill and even catatonic patients. Inspired by these observations, the Austrian physician Julius...
  15. J

    He Got Schizophrenia. He Got Cancer. And Then He Got Cured.

    https://www.nytimes.com/2018/09/29/opinion/sunday/schizophrenia-psychiatric-disorders-immune-system.html?rref=collection%2Fsectioncollection%2Fopinion&action=click&contentCollection=opinion&region=stream&module=stream_unit&version=latest&contentPlacement=4&pgtype=sectionfront Interesting........
  16. J

    Mycoplasma infections in people with ME/CFS

    @James Morris-Lent Would you mind sharing which antibiotic helped you? Thanks
  17. J

    Lofepramine/phenylalanine for fatigue

    Hello, There was some research into looking at a combination of lofepramine and phenylalanine to treat fatigue in MS. It looks like it had a marginal effect https://www.ncbi.nlm.nih.gov/pubmed/12185153 and https://www.ncbi.nlm.nih.gov/pubmed/12376086. Anyway a company called Multicell...
  18. J

    Mycoplasma infections in people with ME/CFS

    Hi, In the late 1990's early 2000's there were several studies looking at mycoplasma infections in CFS, and researchers generally found much higher mycoplasma infection rates in PWCFS than healthy controls, e.g. https://academic.oup.com/femspd/article/34/3/209/558832. Doesn't seem like there...
  19. J

    Cyclophosphamide drug questions?

    Thanks—I had kept hearing early 2018.
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