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Bearing in mind I do not have ME. I was in the RAF when I caught Glandular Fever at the age of 18 in the early 1970s. I gather other cases could be a lot worse than mine, but nonetheless I was hospitalised for 2 weeks, given 3 weeks sick leave, and put on light duties for some time after that...

I suspect that statistically there will be a subset of people who maybe are misdiagnosed with ME/CFS, when in fact they have CF ... possibly also deconditioning being a contributor to that. (I mean, what are the odds there will not be some folks in that category?). But because nobody knows (and...

Yes, I can understand that, and have pondered much the same thing regards my wife, though she does seem to tick many of the ME boxes. I think one thing is important: just supposing what you said came to pass, and a biomarker was found which clearly identified "ME sufferers" having a physical...

It's hardly surprising they are confused though, when the likes of MS, NICE, etc, speak of CFS-also-known-as-ME, CFS/ME, and yet MS seems himself to be very confused/forgetful when he then says in the next breath CFS and ME are not the same thing. Talk about identity crisis.

And swans' eggs are very large.

The success of propaganda depends on the psychology behind it, so will be affected by how skilled the propagandists are at psychological techniques ... :rolleyes:.

Not found exactly what I was looking for, but something fairly close. http://www.virology.ws/2018/01/15/trial-by-error-my-six-month-review/

Ironically those who accuse us of militancy are in many ways simply reflecting their own strategy rather than ours.

Absolutely. So if later commentary by MS suggests PACE participants were recruited under false pretences ... what then? @dave30th ?

But they seemed to still report they were improved or about the same, which in terms of PF/6mwt still shows the same inflationary trend.

There is the potential for some sort of aliasing effect if not careful I imagine, where one blue dot could newly occupy the space someone else's blue dot previously occupied or looked likely to occupy, but the moving images make it pretty clear to see for some dots at least.

If I'm understanding correctly what I'm looking at, this is basically showing that any percentage increase in people's subjective interpretation of their physical function, far exceeded any objectively measured percentage improvement in their actual physical function. (Again with the corollary...

And it also has to be noted that even for that, there is at least one anecdotal statement from one of the GET arm PACE participants (in a response to one of @dave30th's blog posts?) that they essentially exchanged some of their normal physical activity for 6mwt activity, so their overall...

That sounds very valid to me. I find it worrying that, by definition, dropout's data are missing, and too much is presumed about it being irrelevant, when in actual fact that data it may be some of the most important. Especially if the dropout rate is significantly higher on the more physically...

http://www.bbc.co.uk/comedy/waitingforgod/

Not sure if the joke translates into Americanese, so just in case not, there is an expression re very elderly people "Waiting for God". There was also a popular comedy series of that name.

To me one of the greatest indications of sources of bias in PACE, is the deep rooted intransigence of the authors all these years later. With such a closed-minded approach to science, what hope did it ever really have?

Which comes back to the subset of a subset thing.

Watching paint dry :).

:rofl::rofl::rofl::rofl::rofl: