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  1. rvallee

    Rituximab and placebo response

    I think on this one it's safe to say that it simply shows the problems with self-reports from arbitrary questionnaires, particularly that they are detached from objective reality. Maybe a competent bespoke questionnaire would have more accurate results but the typical ones used have little...
  2. rvallee

    Thread for all minutes of the UK CFS/ME Research Collaborative [CMRC] Executive Board Meetings

    Well, no loss then. Of all the nonsense it's the super-condescending nonsense that treats us as stupid children that disgusts me the most. Not really sure what he was doing there anyway. Good riddance.
  3. rvallee

    Medical constructions of long-term exhaustion, past and present; 2015; Lian and Bondevik

    I would suggest that this is true to some extent but much more on the physician side and barely significant on the patient side. Aside from the recent nonsense about Internet-diseases-that-actually-predated-the-Internet-by-decades, the experience of most patients in this scenario is largely...
  4. rvallee

    Biopsychosocial risk factors of persistent fatigue after acute infection: A systematic review to inform interventions, 2017, Hulme, Moss-Morris et al

    Just skimming through but it doesn't appear to be much more than just trying to prop up the usual arguments and simply using a review as a convenient tool that they have been discussed at some point while adding their own prior perspective, as is tradition. It says risk factors but as usual...
  5. rvallee

    Thread for all minutes of the UK CFS/ME Research Collaborative [CMRC] Executive Board Meetings

    Planning to eventually plan for planning. One day. Decade unsure. Does that awareness of "controversies" cover the fact that it is the people who have sabotaged this disease who are themselves the main point of controversy, that it is their very involvement that causes most of the problems and...
  6. rvallee

    London School of Hygiene and Tropical Medicine - LSHTM 120 keynote lecture: Alumni on the frontline of innovation 2019

    The early models of small wind turbines had that problem. It was a very real problem and anyone who has ever dealt with a beeping fire alarm for any period of time understands how even a small whiny noise can be a real pain in the donkey. Not particularly surprising that the people most likely...
  7. rvallee

    London School of Hygiene and Tropical Medicine - LSHTM 120 keynote lecture: Alumni on the frontline of innovation 2019

    A rare point of agreement. Unfortunately he chose to treat his failures as personal success, no matter the consequences to others. He seems a rare animal who acknowledges his failures but seems to treat them as being universal, rather than personal, that his personal failures mean everyone...
  8. rvallee

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    I think it's reasonable to point out that the similarities are superficial. Because it's also reasonable to point out that the people who are confused over this disease are precisely confused over superficial similarities. Sometimes it's necessary to spell things out very, very slowly and with...
  9. rvallee

    The $100 million challenge

    Ron Davis explained it pretty well, I think. Replicate the model used by the genome project. You fund long-term at something to the order of $10M/y (ideally way more but this is the minimum figure he used) to build a research center focused on solving the problem with many different specialists...
  10. rvallee

    The increased cellular permeability syndrome manifesting as severe idiopathic type urinary incontinence, 2019, Check & Check

    There's a whole lot to unpack here and I'm not sure how we get from cellular permeability to urinary incontinence and sprinkle in some fibromyalgia and CFS in the process...
  11. rvallee

    Sleep may trigger rhythmic power washing in the brain

    You should use the delicate cycle instead.
  12. rvallee

    The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model, 2019, Geraghty et al

    They have a set list of excuses for that. If you don't like the first one they have another, and then another and so on and on. Always ending with thought-terminating clichés like "you just don't like psychology" or whatever, nevermind that we don't have much opinion on that or that some ME...
  13. rvallee

    The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model, 2019, Geraghty et al

    That's mostly what it is. Simon Wessely is a big fan of mass hysteria, sees it everywhere and he is not alone in this. He made the same pronouncements on no less than 4 other patient populations and has a weird obsession with fear playing a major role in ME. No idea where he got this nonsense...
  14. rvallee

    The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model, 2019, Geraghty et al

    Depression patients would make a lousy control group. The diagnosis has basically no reliability, I'd be surprised if when we get a reliable test we don't find 50%+ error rates, and they are often heavily-medicated, introducing external effects that comparison groups should avoid. I'm not really...
  15. rvallee

    NEJM Journal Watch: Interview with Dr. Caleb Gardner on the limitations of an increasing focus on biologic knowledge in psychiatry

    Couldn't even follow his own advice, uh? He has behaved towards us like a petulant child who feels entitled to be celebrated no matter what he does for the mere fact that he is present.
  16. rvallee

    The effect of concomitant fibromyalgia in HIV infected patients receiving antiretroviral therapy: a prospective cross-sectional study, 2019, Demirdal

    Abnormally high. Suggesting either poor diagnosis or that the aforementioned widespread pain found in HIV patients is similar to FM, to a degree anyway. Right idea, but detection doesn't mean diddly-squat without useful treatments. Proper treatment would to those things, not mere detection...
  17. rvallee

    Effects of attachment-based compassion therapy on brain-derived neurotrophic factor and inflammation among fibromyalgia patients, 2019, Montero-Marin

    I thought Nature was better than this. Clearly not. Looking forward to studies on the effects of high-intensity Feng-shui on surgical outcomes or testing crystallized homeopathic astrologically-aligned fortune cookies as a prevention against, I don't know, headaches, or whatever. So multiple...
  18. rvallee

    Video: Upright Activity and Exercise Intolerance: Critical Concepts in the Evaluation of Chronic Fatigue, Dr Lucinda Bateman, 2019

    I'm not really sure what's the hangup with environmental medicine or why it's controversial. I get that some people use it to promote weird ideas but if that's someone's excuse then they should feel that even more towards psychosomatic medicine. Which they usually don't. It's not as if it's...
  19. rvallee

    Acute effect of strength training on mood of patients with fibromyalgia syndrome, 2019, Andrade et al

    How many FM patients would rank "mood states" in the top 10 of their needs? Not in %, in absolute numbers the world over? Definitely less than 3x12. Especially as mood is itself a direct consequence of the illness. Like trying to catch smoke with a net and arguing that it takes care of the fire...
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