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You take this 3 times per day, so i don't think you can just take one before bed when you think you need it and expect any results. @NelliePledge It's not like melatonin in that regard, or a sleeping pill.

@Sunshine3 Please see question in #11, above. Thanks!

I sleep 9-11 hours per night. Less than 9 and I'm barely functional. If I don't set an alarm, which is most of the time, I sleep 10-11 hours. I used to have terrible "tired but wired" problems (up til 3 or 4 am), but that has come to a screeching halt since I started taking N-acetyl cysteine...

I'd also be chary of sales representations re these issues unless you get in writing exactly what will be used. This caution is based upon experience.:(

Thanks for this. It helps me understand other developments, like the release of the minutes of the two "oversight" bodies.

Thank you, @Sasha! I gather that, if they want to fight it, they would go to a tribunal?

What is the ICO? What is the significance of this for members who don't know the legal setup in the UK?

Oh, @dreampop, we've all been there. :hug:

I'm blown away by the quality of thought and writing in this submission, and in the many serious discussions on this forum. It's also thrilling to me to contemplate the possibilities the forum offers for interacting with researchers and impacting the field of ME/CFS research to our benefit...

I'm not aware that this has been established. I've had several courses of IVIG with no impact whatsoever on my ME.

Too bad you're having such difficulty, @Arnie Pye . There's nothing worse, seems to me, than sleep troubles. They seem to prompt such frustration and misery. I hope you can come to a place of comfort soon. :hug::hug:

you're right.;) I am going a little off topic here. :(

I don't get your point. What's a load of crap?

It's true that nobody recommends going to bed and moving as little as possible, but there's lots of evidence that the source of calories matters a whole lot more than number of calories. So deep calorie restriction isn't necessary for weight loss, provided carbohydrates are restricted to 50-100...

I don't have expertise in this area, but my understanding is that current thinking is that exercise, while important for cardiovascular health, has little significance in weight management. Even healthy people, living a normal life, can't do the amount of exercise necessary to effect weight...

It appears they tout their patient involvement in the development of this instrument. Makes me wonder how they did on the criteria set out by Jennifer Johanneson in the article posted by @TrixieStix on Sunday. Sorry. Don't have the brainpower to figure out how to post a link. :(

Thank you, @Leonard Jason , for including your team's latest efforts to define PEM. I have four comments: 1. I'm not sure if, on a bad day, I could understand and answer such a lengthy questionnaire, so the circumstances under which the questionnaire would be used are key; 2. This iteration...

Well, then, :wtf:!

Maybe I misunderstood the article. I thought that the civil servant was openly pointing out that the bps theories were running along with the social theories sub rosa, thus basically outing and criticizing the plans on this basis.

@Squeezy :hug::hug: