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Abstract Introduction: Fibromyalgia (FM) is a chronic fluctuating, nociplastic pain condition. Naltrexone is a µ-opioid-receptor antagonist; preliminary studies have indicated a pain-relieving effect of low-dose naltrexone (LDN) in patients with FM. The impetus for studying LDN is the...

"Chronic disabling fatigue and depression at age 18 years Chronic disabling fatigue and depression were assessed at age 18 years using the self-administered computerised version of the CIS-R.62 We included a measure of depression to test for potential confounding effects of depressed mood...

Authors: Lisa Quadt1, Jenny Csecs2, Rod Bond3, Neil A Harrison4, Hugo D Critchley1, Kevin A Davies5, Jessica Eccles1 Abstract Objectives To test whether inflammatory processes link the expression of childhood neurodivergent traits to chronic disabling fatigue in adolescence. Design...

From a quick scan, unfortunately not.

Part of the book series: Current Topics in Behavioral Neurosciences Abstract For neurotypical adults, a single bout of low-to-moderate intensity physical activity usually transiently improves feelings of energy. Similar bouts of exercise have the opposite effect of increased feelings of...

"#ThereForME is a campaign founded by Karen and Emma, two carers for partners with very severe ME/Long Covid. #ThereForME is calling for an NHS that's there for people with ME and Long Covid." https://linktr.ee/ThereForME (Provides many links, including to an executive summary of the "Building...

The case report and review that the news reports are based on, Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature Abstract The prevalence of autism has been increasing at an...

Was when I posted, looks like they changed it.

Maeve Boothby O’Neill’s inquest has already highlighted how little doctors understand ME/CFS: It's only day one https://www.thecanary.co/opinion/2024/07/22/mecfs-inquest-maeve-boothby-oneill/

From the Guardian article, "At the start of her inquest in Exeter, it was revealed that Boothby O’Neill’s GP, Dr Lucy Shenton, who had worked hard to get her help, would not appear to give evidence because she had suffered post-traumatic stress disorder over the case. The coroner, Deborah...

Objective Insomnia disorder is the most common sleep disorder. A better understanding of insomnia-related deviations in the brain could inspire better treatment. Insufficiently recognized heterogeneity within the insomnia population could obscure detection of involved brain circuits. The present...

@dave30th , please see the two posts above. In particular, I would be concerned if I received that. Even if there were to be an obvious link between your first name and username here, I can't see why Dave, or the University of Berkeley, would need to have that connection confirmed.

Abstract Background Brain imaging studies investigating grey matter in functional neurological disorder (FND) have used univariate approaches to report group-level differences compared with healthy controls (HCs). However, these findings have limited translatability because they do not...

Published papers thread for w/c 15th July. Facebook: https://www.facebook.com/sci4me/posts/pfbid0mqMttqtokBrWEiXU72JyaTdtihA5TXE9n3JQFS4XBeZDBdE6VWEiiT5uFJnFTuyGl Mastodon: https://med-mastodon.com/@s4me/112829177096763397

Trial By Error: “Effort Preference”? WTF? "...I mention this as a way of highlighting my initial reaction to the long-awaited and long-delayed publication of the US National Institutes of Health’s study of 17 ME/CFS patients, along with 21 healthy controls. The paper, titled “Deep phenotyping...

Abstract Long covid (persistent COVID-19) is a new disease with contested aetiology and variable prognosis. We report a 2-year ethnography of UK long covid clinics. Using a preformative lens, we show that multidisciplinary teams (MDTs) built working knowledge based on shared practices, mutual...

Highlights The molecular weight distribution and monosaccharide composition of licorice polysaccharides changed to a certain extent before and after honey-processing. Both raw licorice polysaccharides (RLP) and honey-processed licorice (HPLP) can improve chronic fatigue syndrome, and the...

News in Brief posts for w/c 15th July. Facebook: https://www.facebook.com/sci4me/posts/pfbid02kjFcrBgjgeYUmYY1YPARQi6Cfshx4cjmQDrxhC4WUpfxVke6nxw6UKWXxcHbAT7gl Mastodon: https://med-mastodon.com/@s4me/112823670278247428

The title of this article now includes "syndrome"; "Long COVID & Chronic Fatigue Syndrome: The Similarities are Uncanny".

Abstract Background Patients with Functional Somatic Symptoms (FSS) are frequently encountered within healthcare settings such as Emergency Departments (ED). There is limited research regarding characterisation and frequency of FSS within frequent presenters to ED and no previous Australian...