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Fibromyalgia is a complex chronic pain condition characterized by widespread pain, fatigue, cognitive dysfunction, and sleep disturbances. People with fibromyalgia can experience both autonomic and somatic disturbances, cognitive and mental health symptoms, and hypersensitivity to external...

"Studies showed an excess annual cost associated with FND (range $4,964 to $86,722 2021 USD)" Only a small variation then.....

Introduction Functional Neurological Disorder (FND) represents genuine involuntary neurological symptoms and signs including seizures, weakness and sensory disturbance which have characteristic clinical features, and represent a problem of voluntary control and perception despite normal basic...

Full title: Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population Purpose The effect of postural orthostatic tachycardia syndrome (POTS) on health-related quality of life (HrQoL) remains poorly studied...

13 patients in one year!! Not sure where the extra patient came from, considering only 11 agreed to participate.

Background Functional neurological disorder (FND) is a disabling condition which has poor prognosis without treatment. This study aimed to evaluate the effectiveness of an outpatient integrated multidisciplinary intervention for the condition. Objectives This study aimed to assess the outcomes...

Objectives Paediatric Chronic Fatigue Syndrome (pCFS) is a common condition that significantly disrupts a healthy psychosocial development. Psychiatric symptoms associated with pCFS are conceptualized as either part of its complex etiology, its consequence, or as a comorbidity. However...

Published papers thread for w/c 12th June Facebook: https://www.facebook.com/sci4me/posts/pfbid0fBBqm2qh2pDSX59egKeY6pX6VMAQWT4XkzRtsQy9kdy83sNKgxiFp1GjS76QLbnFl Mastodon: https://med-mastodon.com/@s4me/110570055663213355

"In my early years as a doctor, I thought it was my role to be positive, sometimes overly positive, with patients and their next of kin, reassuring them of a low likelihood of my worst suspicions being confirmed. Yet I started to find myself regretting what I had said, especially when a hunch...

News in Brief posts for w/c 12th June Facebook: https://www.facebook.com/sci4me/posts/pfbid0GyvmCx94WAJzaTVgwQwcnNZb2gxtFdserFgHkWGqeVTRLXeAUQCFGTtMBSyuDwV1l Mastodon: https://med-mastodon.com/@s4me/110565037543595357

Introduction: Idiopathic purpura fulminans (IPF) is a rare and severe coagulation disorder, associated with transient anti-protein S (anti-PS) antibodies in the context of post-viral infection such as varicella. Anti-protein S antibodies are frequently found in the context of varicella, in...

No he's not. He identifies it as a singular illness, i.e. CFS and ME are the same thing, therefore the illness was first called myalgic encephalomyelitis, and was then called chronic fatigue syndrome, and is now called ME/CFS.

Err, no. As we all know, the illness originally called just "myalgic encephalomyelitis".

Could endometriosis be caused by bacteria? Study offers fresh clues "Infection by a particular group of bacteria could be linked to endometriosis, a painful condition that affects up to 10% of women and girls of reproductive age. In a study of 155 women in Japan, members of the bacterial genus...

Abstract Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demonstrated a pathogenic role of Fusobacterium...

Background Hydrogen gas (H2) is a common product of carbohydrate fermentation in the human gut microbiome and its accumulation can modulate fermentation. Concentrations of colonic H2 vary between individuals, raising the possibility that H2 concentration may be an important factor...

Completely expected bog standard response which this petition was always going to receive.

Background Although functional neurological movement disorders (FMD) are characterized by motor symptoms, sensory processing has also been shown to be disturbed. However, how the integration of perception and motor processes, essential for the control of goal-directed behavior, is altered in...

Abstract Lactate shuttled from the blood circulation, astrocytes, oligodendrocytes or even activated microglia (resident macrophages) to neurons has been hypothesized to represent a major source of pyruvate compared to what is normally produced endogenously by neuronal glucose metabolism...

Abstract Previous studies on the natural history of long-COVID have been few and selective. Without comparison groups, disease progression cannot be differentiated from symptoms originating from other causes. The Long-COVID in Scotland Study (Long-CISS) is a Scotland-wide, general population...