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  1. Kitty

    Mike's EU Marathons

    That is amazing – and so much money raised. What a guy!
  2. Kitty

    Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test, 2019, Morten, Newton et al

    I find all this incredibly irritating – I've never had it from a doctor, but before I was diagnosed, lots of colleagues suggested dietary 'solutions'. (Luckily, it did stop once I knew what was causing the symptoms.) However, I am curious about the odd intolerance to glucose experienced by many...
  3. Kitty

    Options for genetic testing

    Before you decide, it might be worth asking whether this kind of testing will tell you anything reliable about your ability to absorb or utilise B vitamins. Having a particular variant may not determine how your body works, as genetic traits often have highly variable penetrance, and there may...
  4. Kitty

    UK Genome Wide Association Study (GWAS) project - draft website goes live, feedback sought on recruitment plan, and updates

    @Jonathan Edwards – don't you see the window containing the survey?
  5. Kitty

    IDO2 gene mutations - SNPs

    I have to go out, but I'll do this one because it's fairly straightforward: The symbol '>' is used to indicate 'greater than'. So 9>8 just means 9 is more than 8. '<' means 'lesser than' in the same way. T>C usually indicates that more people in the sampled population have the T allele than...
  6. Kitty

    UK Genome Wide Association Study (GWAS) project - draft website goes live, feedback sought on recruitment plan, and updates

    I think this is the right approach. There must be a lot of people whose only 'evidence' is a sentence in their GP records written many years ago, which is copied to their list of diagnoses and meds. Given the lack of objective tests, it isn't really evidence anyway.
  7. Kitty

    Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (2019) Karhan, Unutmaz et al

    I have a friend with MS, who I've realised was due to have several infusions of this same drug – she'd told me the generic name, which is why I didn't recognise it. It was then put on hold whilst some kind of safety review goes on, and she now has no idea whether or not she'll be able to have...
  8. Kitty

    UK Genome Wide Association Study (GWAS) project - draft website goes live, feedback sought on recruitment plan, and updates

    The fact that this is a genetics study might at least reassure people that it's nothing to do with the BPS brigade? I agree that ME patients are factionalised (why wouldn't we be, given our history!), but we just have to keep explaining. No study will meet with everyone's approval, but I sense...
  9. Kitty

    IDO2 gene mutations - SNPs

    The rsids are given at the top of the table you mention. They appear to be: rs10109853 rs4503083 rs4736794 rs35212142 rs774492001 Not all of them will necessarily be reported in direct-to-consumer genetic testing. This means that the reference (more frequent) allele is C and the alternative...
  10. Kitty

    BBC website Motor Neurone Disease link to cholesterol

    I saw this yesterday. It's interesting, but the headline's oddly misleading – it suggests the research is mostly about the most devastating form of the disease, when in reality it's more about the hereditary spastic paraplegias. It also reads as if high blood cholesterol could cause the disease...
  11. Kitty

    Silent clock

    Just tried asking Siri on my iPhone, and there's very little light when it answers. It doesn't work with the phone face down, unfortunately, but it does with a black sock draped over the screen. I suspect it'd work on most smartphones. If anyone does ever want a non-ticking clock, by the way...
  12. Kitty

    UK Genome Wide Association Study (GWAS) project - draft website goes live, feedback sought on recruitment plan, and updates

    Here goes with another one of my daft ideas. I'll say it anyway, though, just in case anyone can come up with anything better! What if one of the major ME charities or groups put up a very simple online survey, asking people with ME to click whether they would – or wouldn't – be willing to take...
  13. Kitty

    BBC Radio 4: The Misinformation Virus

    No, different focus altogether!
  14. Kitty

    BBC Radio 4: The Misinformation Virus

    :rofl: Heard it go out live yesterday, it was quite interesting. They looked into how misinformation spreads, and the fact that the way the internet is structured can actually exacerbate the effects even before the bots get going.
  15. Kitty

    Blood pressure monitors and how to use them; taking a blood pressure measurement; continuous monitoring

    My Moron seems okay too – I asked our practice nurse which model she used, and bought the same. Readings have always been in line with those done the old-fashioned way by the GP and the rheumatology clinic.
  16. Kitty

    Discussion of documentary: What about ME? (2016)

    If this is the case, it might even suggest that those who benefit may have something other than ME. Depends how big the cohort was – but if, say, only one person out of 20 benefits, it begins to look fishy.
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