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I cannot see that that has any justification. If almost everyone has been vaccinated then what is the reason to link symptoms to the vaccine? I have not read through everything in the article but from reading most of it it just seems that there are a few medical people with a hunch. Considering...

It was June 2017. I was interviewed on June 14th. The person initially interested was a relatively junior BBC journalist I think with a family member or friend with ME. She seemed to be quite keen on Willy Weir's idea of ME being due to a retrovirus. Michael Buchanan is a heavyweight who was to...

And I think JemPD may well be right. Some journalists are bright cookies, but the majority who make BBC documentaries are more into a fashionable story.

It is a worthy idea. We nearly got Newsnight interested in, I think, 2017, but I was interviewed the night of the Grenfell Tower fire and for whatever other reasons the momentum was lost. But as you say, a lot more has happened since. A simple point is that the BPS illness model is not that ME...

The BMA is a doctors' union. They could say that urgent biomedical research in to post viral illness in doctors is essential but it might sound a bit hypocritical!

This really should be applicable to ME. It is quite different from just measuring how much activity people do. The result is the pattern of acceleration identified. PWME ought to have signature pattern, or maybe two or three different patterns. A study like this for ME would be much cheaper tha...

An interesting question. A lot of good points have been made. My initial reaction is that there should be a primary outcome measure that is based on how many people show a specified improvement on a scale as suggested by Ravn: (a simple visual-analogue scale going from I feel well to I feel...

But do we even know that drinking more water is useful for OI? I think it is quite unlikely to be helpful for most causes of OI and there are several, so there is unlikely to be a general rule. The images suggest there are people who think they know how to solver the problem of getting people...

I cannot load that link.

I agree that much of the is sympathetic butDrEnglish seems to be confusing two different things. Skepticism permeates our profession. It is ingrained during medical training and reinforced by professional experience. (…) Skepticism is widely perceived as the prudent, conservative way to deal...

This paper is too complicated for me to unravel but I have a thought that some others might sort out - I rarely get let down by PWME. Fibronectin circulates in plasma and gets included in fibrin clots as I understand it. So measuring it is serum, which is plasma that has clotted and had the clot...

A member of my family has been in a London hospital for five months of this year. They are a medical professional like me. It is very clear from the experience that the service will continue to be unsafe and ineffective until basic nursing pay becomes realistic (maybe a 50% increase) and working...

Not really any greater thoughts than you have admirable expressed @Obermann. The additional problem with ICC is that it brings in all sorts of hypothetical aspects of ME/CFS and asks for symptoms to be evidence of those rather than just looking for stable clusters of symptoms. To my mind it is...

The website would compete with the Monty Python Dead Parrot Sketch (or Yorkshire Airlines) if it wasn't that this isn't a joke.

This shift in criteria sounds like an excellent idea to me. There is often a tendency to be too restrictive about recruitment criteria because of worries about comorbidities confounding results. It may have been a good idea to be very strict at the beginning but I doubt there will be problems in...

Yes. My grouse is that you need to distinguish between monocytes in blood that might by drawn out into tissues full of cytokines from all sorts of sources, like neutrophils, and inflammation full of macrophages making cytokines that call in more cells and therefore drive the inflammation...

It is good to see people at leat trying to measure these things. I guess I wish they would be more realistic about interpretation. I have not had time to read the whole paper. I am wondering if we can be sure that the people with the symptoms and raised markers have symptoms because of Covid...