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So it seems that next time they do a trial, or indeed when they do routine treatment, they will have to, in the information sheet for patients, explain that the treatment involves persuading people to think they are doing more, even though doing more does not actually make them better, it is...

I don't actually see any reason to think that is necessarily so. What is post-cancer fatigue anyway? I am not aware of ever having come across someone who had prolonged fatigue after successful treatment of cancer. And I have looked after sores of people in that situation. I strongly suspect...

From the introduction: A previous study of our research group showed that an increase in objective physical activity did not mediate the effect of CBT on severe post-cancer fatigue [6]. This was also found in CBT for chronic fatigue in other patient populations (e.g., chronic fatigue syndrome...

I need to read the paper but this seems a but crazy. I thought CBT for fatigue consisted in persuading people that is they were more positive about doing more activity they would discover they felt better. So the CBT group without activity would be told that if they were more positive --- er...

Nice to see her recommending a review of over diagnosis by Henrik Vogt too. Cheap and cheerful - no need to find out what is wrong - better to leave it as medically unexplained and do lots of exercise.

Recent studies by people like Lipkin indicate that the viral load in PWME is no different from normal.

Denmark IS an archipelago.

It is tempting to speculate that underneath all this is some clandestine organisation such as a cabal or the Freemasons. So the truth is evil now? That sounds fairly standard for certain part of the globe these days. All dreadfully Shakespearian I guess - or maybe Marlowe in disguise. I have a...

Would that be the Scottish Play, not otherwise to be mentioned, or is this more a case of the PFink of Denmark?

It is very lukewarm, yet there is still the sort of sloppy wording that suggests that the people doing the study fail to understand the real problems. They say: 'For all studies comparing some form of psychological therapy with usual care or a waiting list that could be included in the...

It does not look like a rigorous scientific study to me. Almost nothing is said about controls. In general these antibodies tend to turn up I almost any situation people look for them in. Anti-muscarinic receptor antibodies have become a bit of a joke in neuro-immunology. From my perspective...

I think I might be gearing up for February 2021 for NZ. If there are relevant events then I might be able to get involved.

Actually I think we can be pretty sure that NICE are making their own analysis. (They said they would and I have reasons to think they are sticking to that.) Cochrane reviews are a source for NICE but NICE does not use the Cochrane GRADE assessment per se. The people on the NICE committee are...

That may be so but I suspect very few actually look at Cochrane reviews. The great majority will look at government guidelines. If Wikipedia is misleading then if NICE changes its mind it can be documented there.

I am not sure it matters any more. All the people to whom the review is relevant are now well aware that a lot of people think it is incompetent. They may or may not agree but that is another issue. What matters in the UK is NICE and I suspect other countries that might be looking over their...

I am afraid I will be at a conference in Glasgow on arthritis then but I am planning to get to NZ one of these days.

Interesting proposal - where did you find it may I ask? @Lisa108

It is interesting that this article is written by a trainee - a fellow, or in the UK a registrar. How does he know so much about what is wrong with his speciality. Wouldn't one expect an article like this to come from a senior expert? The text is very similar to something we have seen from...

I assume this is all a response from the NICE data gatherers. My impression was that they are taking things seriously. It is so easy for good intentions to turn into handle turning but like you I am getting more hopeful that sense will prevail.

Cochrane need to understand that all trials of this sort are worthless. Cochrane clearly does not understand that. Until it does its opinion also seems to be worthless.