I would add the search for a viral reservoir. Labs like PolyBio have lots of ideas for studies, and more money would surely speed trials along, for example with the expensive equipment necessary for specialized scans.
Isn't there an issue of scientists avoiding even entering the field because of lack of research funds? Where they don't want to devote their life to something where every grant will be rejected?
Hmm, yeah, I hadn't looked at it from the angle that many deconditioning markers might depend on normal muscle function in order to be similar across conditions (although we're not sure muscle function is even normal in ME). Another option could be people paralyzed from the neck down from spinal...
And please also compare to very deconditioned or other unhealthy people so we know whether or not the biomarkers are found in all deconditioned or unhealthy people. In that linked thread, we brainstormed some potential deconditioned control groups, such as bedbound hospital patients or people...
Merged posts
And please also compare to very deconditioned or other unhealthy people so we know whether or not the biomarkers are found in all deconditioned or unhealthy people. In that linked thread, we brainstormed some potential deconditioned control groups, such as bedbound hospital patients...
That's wild. It sounds like they're just saying choose whichever option returns the largest desired effect.
Do they go on to explain how to decide whether or not to include single responders?
I'll paste what I previously said on the forum:
I'll say that it's very hard to notice that you're doing an activity because you've already improved a small bit, and not the other way around, and I can see why someone would be absolutely sure it healed them if they stay well afterwards and...
More info from the Facebook post:
"Pre-recorded interviews from experts —
- Linda Tannenbaum, founder and CEO of the Open Medicine Foundation.
Interviewed by Derek Muller from Veritasium.
- Dr. David Kaufman, an ME/CFS specialist.
Interviewed by Vanessa Hill from
BrainCraft.
- Dr...
Will be hosted by Simone Giertz and Ian Hecox (second person is half of the Smosh channel), fellow Youtubers with 2.72M and 26.7M subscribers respectively.
Live stream will be on the Physics Girl Youtube channel.
Thread for previous study by the author:
Cutaneous α-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease, 2023, Gibbons et al
Thread for study of α-synuclein in POTS:
Cutaneous alpha-synuclein deposition in postural tachycardia patients, 2021, Levine et al
"Follow up studies are in the works.
Both NIH RECOVER and CND Life Sciences will be investigating the prevalence of the #Parkinsons biomarker in #LongCovid via skin biopsy."
"This will be an excellent complement to the post-COVID RT-QuIC (another PD biomarker) study coming out of Innsbruck."...
Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies
Authors
Abstract
Importance Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system...
She's almost certainly not writing any of this herself. Almost all her tweets are written by her husband. I'd assume he would be pretty familiar with terminology by now, but maybe it's someone else from her team that did this one.
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