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Abstract The current pandemic of coronavirus disease 2019 (COVID-19) has affected >160 million individuals to date, and has caused millions of deaths worldwide, at least in part due to the unclarified pathophysiology of this disease. Identifying the underlying molecular mechanisms of COVID-19...

Stanford researchers quickly isolate rare, allergen-reactive white blood cells, called basophils, using microfluidics and magnets. The new device could help revolutionize allergy diagnosis from the current slow and painful process of skin tests and oral food challenges...

My disability benefits claim early on (w/o cognitive impairment and PEM at the time) was based on my history of relapsing-remitting M.E, and not 'mild, moderate or severe' category.

Desperate sufferers who believe they have exhausted the therapies offered by conventional medicine sometimes look elsewhere for help. They often take their cues from the media, which trumpet each small trial result as a major breakthrough, even in the absence of rigorous scientific testing.

@duncan I'm not comparing it to bleach. My biggest issue is the overly misdiagnosing of patients who are mislead by militant social media groups. I have not walked in the shoes of chronic lyme patients, but I had a best friend who was misdiagnosed and had a PICC line inserted for 9...

Québec ME/CFS patients deserve access to new long-Covid clinics, advocates say. The network of clinics will focus on long COVID and Lyme disease, but not myalgic encephalomyelitis, leaving patients with the complex illness feeling forgotten again...

Posts moved from this thread: The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread Absolutely. The advocacy community commonly argues that chronic Lyme disease is grossly underdiagnosed and is responsible for an...

Abstract Bile acids modulate cell functions in health and disease, however, the mechanisms underlying their actions on neoplastic cells in the gastrointestinal (GI) tract remain largely unknown. In this issue of the JCI, Noto et al. comprehensively analyzed how interactions between Helicobacter...

Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis, 2022, Jennifer M. Noto et al Abstract Gastric carcinogenesis is mediated by complex interactions among Helicobacter pylori, host, and environmental factors...

Key clinical point: Women vs men with multiple sclerosis (MS) showed greater inflammatory disease activity up to menopausal age, whereas men vs women with MS showed greater disability accrual. Major finding: Women vs men had a 16% higher relapse rate and a higher estimated marginal mean of...

@JemPD I missed the point you made about proper wording and how it relates to M.E. My Disability Tax Credit renewal is not based on a diagnoses, but how my disability impairment affects my day to day life, so there isn't a specific guideline to M.E.

You could also add that physical energy expenditure negatively affects your cognitive impairment and vice versa. I described this in more detail when I filled out my Disability Tax Credit form and my GP approved it.

Yes but 'brain fog' is not very descriptive. It's a general term. My sister has Hashimoto and says she has 'brain fog' when she eats certain foods. I use the term cognitive impairment which describes having difficulty concentrating/remembering, learning new things and making decisions...

Budding yeast cells with high levels of ATP do not lead to abnormal aggregation of proteins (magenta), while mutant cells with low levels of ATP exhibit clumps of proteins (magenta). Taken together, Takaine et al.’s results suggest that ATP plays a role in stopping proteins from sticking...

Abstract Adenosine triphosphate (ATP) at millimolar levels has recently been implicated in the solubilization of cellular proteins. However, the significance of this high ATP level under physiological conditions and the mechanisms that maintain ATP remain unclear. We herein demonstrated that...

https://www.mass.gov/news/massachusetts-public-health-officials-confirm-case-of-monkeypox https://www.statnews.com/2022/05/18/spain-portugal-report-monkeypox-cases-raising-specter-of-wider-outbreak/

I inhaled a clove cigarette in the early 80s and my head raced. Cloves(eugenol) and help clear respiratory disorders.

The formulation was ChronoMag in the study I posted. https://pubmed.ncbi.nlm.nih.gov/29524192/ Abstract While general recommendations are for 300-mg magnesium intake a day, an advanced low-dose formulation of magnesium chloride, ChronoMag®, was designed to provide 100 mg of magnesium...

Abstract Patients suffering from fibromyalgia often report stress and pain, with both often refractory to usual drug treatment. Magnesium supplementation seems to improve fibromyalgia symptoms, but the level of evidence is still poor. This study is a randomized, controlled, double-blind trial...

Sudden viral onset-->6 months was able to go to school and do some exercise (no PEM) but losing stamina-->'recovered' after 3 months, went back to work-->relapsed less than one month later--> was still able to do some light exercise without delayed typical PEM. My guess is that M.E was...