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  1. hotblack

    Open DSQ PEM survey - DePaul University, open October 2025

    Really well put @StellariaGraminea and I agree it’s very hard to recognise let alone understand or accept things if we have neither experienced them nor been taught about them.
  2. hotblack

    Relaxing music for sleep

    Or loud neigh-bours? Sorry.. ;)
  3. hotblack

    Relaxing music for sleep

    My top music tips are BBC 3 Night Tracks https://www.bbc.co.uk/programmes/m0008w2m Max Richter Sleep https://en.wikipedia.org/wiki/Sleep_(album) I listen to the first when going to sleep with a timer to stop playing. And if/when I wake up in the night have a Siri shortcut I can trigger to...
  4. hotblack

    MRC/NIHR DecodeME Showcase meeting online and in person Nov 6th

    Sometimes it’s as simple as what limit is on the Zoom license (or whatever platform they’re using)
  5. hotblack

    United Kingdom: Action for ME's PRIME project - research infrastructure

    Great interview. Thanks to Chris and David. Really good to hear more about the project. Clearly a lot of work going on from a lot of people behind the scenes but the collaboration between AfME and Chris seems to continue to be really productive. We’re lucky to have people like this working on...
  6. hotblack

    UK Action for ME Big Survey 2025 - closes 27/1/26 (UK residents only)

    Oh no, hope it doesn’t knock you back too badly and you feel better soon :hug:
  7. hotblack

    United Kingdom: Action for ME's PRIME project - research infrastructure

    Audio only version for those who want it available here (audio ripped from youtube and converted into low bitrate mp3).
  8. hotblack

    UK Action for ME Big Survey 2025 - closes 27/1/26 (UK residents only)

    I’m not sure they do. I’m also not sure if it matters for the goals? This is in their FAQ
  9. hotblack

    UK Action for ME Big Survey 2025 - closes 27/1/26 (UK residents only)

    It is indeed a big survey. But we have plenty of time to complete it and can save our progress. There’s also a version to print and they seem to be offeribg some phone support for people who need it. They were also great at engaging earlier on in the design process. Lots of positives here, well...
  10. hotblack

    Norwegian Fluge & Mella daratumumab Haukeland trial 'ResetME' now accepting international donations

    And already a third of the way to the new target! Nice work :)
  11. hotblack

    Open DSQ PEM survey - DePaul University, open October 2025

    It’s a shame the factsheet hasn’t been read and there’s some misunderstandings here. I completely get what you feel and felt a bit the same at first tbh. I wonder if there’s perhaps a difference or clash in style adding to things here? The length of the response and the point by point detail...
  12. hotblack

    Open DSQ PEM survey - DePaul University, open October 2025

    Some great comments by others which I support and @Nightsong highlights how important it is to get this right. And thanks to @TheDePaulGroup for the involvement and comprehensive responses so far. While we’re discussing differences there is a lot of shared understanding in here too I think...
  13. hotblack

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    I don’t think so and this was the question I had in the other thread about mechanisms of resistance to daratumumab in multiple myeloma There seems to be a lot of focus on NK cell quantity but less on other details which could be important here. I’d like to understand more or find out if studies...
  14. hotblack

    Microsoft releases quantum chemistry tool Skala

    I found this interesting in general and thought others would. A scientific development with potentially relevant applications and also ties in with recent discussion of usefulness of AI/ML. I also think it’s an area @Jonathan Edwards is very familiar with!
  15. hotblack

    Microsoft releases quantum chemistry tool Skala

    Microsoft AI Research has made a tool called Skala available for everyone to use. It was previously an internal research project. Here’s the new Azure Skala page. What is this all about? There’s some info this webpage about the DFT research project Most accessible is probably this blogpost...
  16. hotblack

    Norwegian Fluge & Mella daratumumab Haukeland trial 'ResetME' now accepting international donations

    Great work @Joan Crawford and thank you, am sharing where I can to try and get some eyes and donations to help your efforts
  17. hotblack

    Open DSQ PEM survey - DePaul University, open October 2025

    Agree that focussing on predefined activities is the wrong path. Different people of different severities with different levels of support prioritise different things. This just isn’t an accessible questionnaire, in size or structure. I gave up on it. I believe there will be self selection in...
  18. hotblack

    Development and validation of blood-based diagnostic biomarkers for [ME/CFS] using EpiSwitch®… 2025, Hunter et al. (Oxford Biodynamics)

    Oh yeah… I’d missed that! Thanks both for the explanation. Thanks for the insight. Useful to know.
  19. hotblack

    Trial Report Relationships Between Fatigue, Cognitive Function, and Upright Activity in a Randomized Trial of Oxaloacetate for [ME/CFS], 2025, Vernon et al

    If you did want to Khan Academy has a couple of good modules This AP Biology one And this MCAT module
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