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  1. Forbin

    JAMA -"Advances in understanding the Pathophysiology of Chronic Fatigue Syndrome" by Anthony Komaroff

    It may depend on one's definition of "described." The Ramsay "definition" lists numerous symptoms that he observed in the 1955 outbreak. The 1988 Holmes criteria attempts to create a threshold of symptoms beyond which a patient is deemed to have "CFS." Komaroff has certainly said that choosing...
  2. Forbin

    Nature - News feature: Does psychology have a conflict-of-interest problem?, 2019, Tom Chivers

    The sub-headline and photo caption in the Guardian article incorrectly refers to Marianne Williamson as the "Democratic Nominee." She's a candidate for the Democratic nomination, not the nominee. All you have to do to be a candidate is to meet the citizenship, age and residency requirements and...
  3. Forbin

    Harvard ME/CFS Collaboration Symposium June 8th 2019

    It was interesting to see Dr. Davis go over the "metabolic trap" again. If I have this right... IDO1 converts L-Tryptophan into L-Kynurenine in the cell. If there is too much L-Tryptophan in the cell, IDO1 gradually shuts down and the conversion ceases. If nothing intervenes, L-Tryptophan...
  4. Forbin

    Cognitive Behavioral Therapy "Evidence-Base" Is Exaggerated (Psychology Today)

    Fortunately, CBT research has shown that there's overwhelming evidence that a single course of CBT can keep researchers from exaggerating the "evidence-base" of CBT.
  5. Forbin

    Tinnitus Poll : Making a distinction of subtypes

    FWIW, there seems to be a thing called a "vestibular migraine" which can cause balance problems, tinnitus and some other symptoms, without necessarily producing a headache. Whether this is related to true migraine, or is more of a metaphor, I'm not sure. One website says that symptoms occur when...
  6. Forbin

    Tinnitus Poll : Making a distinction of subtypes

    I've had both c) and d), so I'm not sure which to vote for.
  7. Forbin

    Who is Simon Wessely?

    And yet, the band plays on...
  8. Forbin

    Mental fatigue is linked with attentional bias for sad stimuli, 2019, Watanabe et al

    The paper from which this citation was gleaned also says: The same paper says: The claim that "25% and 50%–75% of patients have a current or a lifetime history of major depression, respectively" is apparently an amalgam of 5 different citations in a paper by Buchwald (so, in the Watanabe...
  9. Forbin

    Red-brown speckles on palm of hands and fingers

    Come to think of it, when I had dyshidrosis as a teen, some of the smaller blisters would often merge into a larger blister. The larger surface of the resulting blister was thin enough to be transparent. Since they were filled with clear liquid, you could use a magnifying glass to look inside...
  10. Forbin

    Royal Free - PACE trial involvement, CBT and GET justification

    I call for the immediate release of this clearly suppressed cytokine data! :) [By my count, the text of the PACE Trial contains the word "cytokine" precisely ZERO times.]
  11. Forbin

    Mouse model of tinnitus - 'neuroinflammation'

    They may not have been trained to react to the absence of the sound created by the gap, but rather to react to total silence - something they couldn't experience with tinnitus. I did wonder, though, how they could be certain that the mice weren't simply deaf.
  12. Forbin

    Mouse model of tinnitus - 'neuroinflammation'

    I think they attempt to induce tinnitus by exposing the mouse to a loud sound. Subsequently, they use a "gap detection test," where another sound is played which has a "gap of silence" in it. The mice have been trained to react to the gap of silence in some way (e.g. they stop licking water)...
  13. Forbin

    'Recovery' statistics

    I doubt it. It's hard to imagine Dr. Bell, noticing that a patient had stopped coming to him, would then, without contacting them, pour over that patient's records to try to see why they had "recovered." He was the only doctor in a town of 800 people. Many of his CFS patients were children.
  14. Forbin

    'Recovery' statistics

    [I originally posted this elsewhere a couple of years ago.] At a lecture he gave in December 2015, Dr. Bell was adamant that 5% of his patients do recover. He was clear that these cases were no different from the other cases he had studied. He had no explanation for their recovery. - - -
  15. Forbin

    USA: Center for Solutions for ME/CFS - news and updates from Columbia University's NIH funded center, Lipkin

    Good to know. I was wondering why the link to the Microbiome Discovery Project (http://microbediscovery.org/) was no longer working...
  16. Forbin

    Gravity-induced exercise intervention in an individual with CFS/ME and POTS, 2019, Ballantine, Srassheim, Newton

    There was a video in which Dr. Hyde referred to the story as being "on the front page" of TIME magazine. I don't think he ever said it was "on the cover." He may have been referring to the "Table of Contents," which could well have been the first page opposite the cover when you opened the...
  17. Forbin

    Gravity-induced exercise intervention in an individual with CFS/ME and POTS, 2019, Ballantine, Srassheim, Newton

    It seems as though the idea is that the autonomic response to changes in position can become deconditioned due to its disuse in people who stay off their feet (or experience extended weightlessness). The exercises seem intended to challenge the ANS with uncommon situations, as when the head is...
  18. Forbin

    Gravity-induced exercise intervention in an individual with CFS/ME and POTS, 2019, Ballantine, Srassheim, Newton

    More information can be found in this dissertation by the author: www.slideshare.net/RobertBallantine/dissertation-final-2408-rab
  19. Forbin

    Do all ME / CFS sufferers have low stamina?

    As other have mentioned, as a teenager I too could only exercise at maximum effort in short bursts. It was in endurance/racing sports, like swimming or running laps, where I would quickly fold - much to my embarrassment. I thought I was just out of shape, but it's almost certain that I had...
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