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  1. Sean

    Elevated blood viscosity is associated with dysautonomia in long COVID symptoms, 2026, Tamariz et al

    Nothing to apologise for. This is what needs to be done with all studies and claims. Torn apart and all the flaws and limitations exposed. It is a core essential part of science, and something to proud of being good at it, which you are. :thumbup:
  2. Sean

    Miscellaneous Research Thread

    While the analytics component is a critical part of overall methodology, and worthy of review on its own, did they also do a separate study on the non-analytical component, the part that constitutes the primary data generation/collection phase? No good checking how robust the analysis of the...
  3. Sean

    What degree of change do we want from an effective treatment for ME/CFS?

    A substantial reduction in pain, brain fog, PEM, and overall increase in the quantity and quality of activity capacity. I will also accept a full cure, a grovelling apology from the medical profession, the guilty being held to prompt formal public account, and a couple of million dollars to...
  4. Sean

    The effectiveness of specialist cognitive behavioural therapy for functional neurological disorder: a service evaluation 2026 White, Pick and Chalder

    Yet another piece of evidence that all they are doing is modifying patients' questionnaire response behaviour, independent of any practical meaningful benefit.
  5. Sean

    Aberrant recruitment of the striatum & insula are associated with recalling and suppressing fatigue- and anger-related memories in CFS/ME, 2026, Rimes

    We are whatever they need us to be for the purposes of the current study. Any and all results, or lack of them, confirm the psycho-behavioural model. I wish that was a joke.
  6. Sean

    Testing a Personalised Dysautonomia Management Protocol in Patients with Orthostatic Intolerance and a Diagnosis of ME/CFS or Long COVID, 2026, Barr

    salt intake to 10 g That is more than twice the generally recommended maximum level of daily sodium intake, and more like 5-10 times the optimal. So it delivers no meaningful benefit, and seriously increases your risk for stroke and kidney disease. Nah. I will pass on this one. :thumbsdown:
  7. Sean

    Norway: 2026 NAV court case over disability benefits

    we can't rule out spontaneous recovery And you can't rule it in either. By its very definition you can't predict it, cause it, or rely on it. It has no role at all in future planning for an individual case. THAT IS WHAT SPONTANEOUS MEANS!
  8. Sean

    Psychological interventions for individuals with long COVID: a systematic review and meta-analysis, 2026, Garriga-Salvó et al

    And which specifically encourages patients to view their symptoms in a different manner, and hence bias the reporting of outcomes. It is blatant systematic biasing of methodology from the start.
  9. Sean

    News from Canada

    :muted:
  10. Sean

    News from The Netherlands

    And worse.
  11. Sean

    Between silence and solutions: a global guideline review of long COVID care and services in Australia, 2026, Luo et al

    integrated, multidisciplinary care models multidisciplinary pathways patient-centred patient-practitioner collaborative model complex, multi-system conditions. Why am I not feeling confident about this?
  12. Sean

    Time: "Do You Have Unexplained Symptoms? They Might Be Post-Viral", 2026

    “we are beginning to realize that there is this whole world out there that we had absolutely no insight into.” Not for the first time in the history of medicine, and undoubtedly not for the last. The problem is that the profession does not seem to learn the lesson from this clear history.
  13. Sean

    Review The hidden pain of bullying: somatic symptoms and physical health consequences 2026 Di Stefano et al

    Relevant studies were identified through a non-systematic search of major electronic databases Not a useful contribution, then. multidisciplinary care :facepalm:
  14. Sean

    ME/CFS Science Blog article - Immune findings in ME/CFS

    +1 The more of my life has been destroyed this disease, the more openly hostile I become to false hope. It is the worst possible response, and both the medical profession and patients need to stop indulging in it. If there is currently no realistic explanation and effective treatment – and...
  15. Sean

    Placebo effect: a psychosomatic component, or only an aggregate of other biases?

    That list is why I constantly bang on about the lack of adequate control in rehab/psychosomatic/BPS studies. They are simply not controlling for all this stuff, and the effect sizes alone that they are getting in the rehab treatment arms are not big enough to rule out those confounders. All...
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