https://www.washingtonpost.com/business/economy/pfizer-had-clues-its-blockbuster-drug-could-prevent-alzheimers-why-didnt-it-tell-the-world/2019/06/04/9092e08a-7a61-11e9-8bb7-0fc796cf2ec0_story.html?utm_term=.1418de0736c6
Not ME/CFS, but provides an overview of the difficulty of new drug...
On PR Phair mentions that he has submitted a manuscript on the metabolic trap to a journal. If this is accepted, it might provide a starting point for pharma companies to begin some type of drug discovery.
On the more pessimistic side, I’m pretty sure Phair et al. don’t really have any idea...
One suggestion--
If folks still have questions on the methods of this paper, a suggestion would be to see if @JaimeS might be able to send Esfandyarpour an email to see if he would be willing to answer questions on this forum. Suggested Jaime rather than doing it myself because I assume that...
@Jonathan Edwards
So in case some weren't able or willing to access the above cited PR thread:
Phair says that every time there is a good case for a dysfunction in energy production, there is an offsetting case for there being no dysfunction. He mentions that Paul Fisher's talk in Australia...
Living With Lyme Disease, Stronger With Love
Brian Nicholson thought Brooke Geahan was the most beautiful woman he had ever met. He also knew that she was very ill.
https://www.nytimes.com/2019/05/24/fashion/24VOWS-Sonoma.html
1) No such thing as chronic Lyme, correct?
2) She got better from...
thanks.
Is a lot or a little? (from above study)
The experimental group: Patients were asked to take 1 g oral capsule containing EPO every 12 hours for 3 months in addition to the standard treatment for their disease.
I assume that there is no livestream of the conference?
Also if anyone from here is going to the conference, would really appreciate it if anyone could ask Dr. Fluge when he anticipates submitting the cyclophosphamide manuscript for review (or maybe it is under review?).
Thank you.
https://www.s4me.info/threads/erythrocyte-deformability-as-a-potential-biomarker-for-chronic-fatigue-syndrome-davis-et-al-2018.6938/page-6#post-127447
Looks like @alex3619 is not a fan
What happens after surgery? Does your head pop out more from neck/shoulders? Can you turn your head like a normal person? Like an owl?
What are the potential complications?
@Jonathan Edwards
It looks like Robert Phair agrees with you that there is no compelling evidence for dysfunctional energy production in ME/CFS.
Here
https://forums.phoenixrising.me/threads/the-ido-metabolic-trap-guy.62727/page-15
Summary
Author doesn't believe existing explanations (which are admittedly unusual) for observed symptoms (fatigue, brain fog, etc.). Therefore it is likely "functional disorder", which I think means "it is something, but we don't know what it is". Only interview people who agree with FD...
Merged thread
https://www.nytimes.com/interactive/2019/05/15/magazine/diplomat-disorder.html?action=click&module=Editors Picks&pgtype=Homepage
An “unknown energy source” has been
blamed for debilitating symptoms
suffered by Americans posted in Cuba.
The real cause may be more surprising...
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