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  1. J

    Pfizer had clues its blockbuster drug could prevent Alzheimer’s. Why didn’t it tell the world?

    Well not totally not ME/CFS. Enbrel (etanercept) is one part of the two drug combo proposed by Nancy Klimas to treat ME/CFS.
  2. J

    Pfizer had clues its blockbuster drug could prevent Alzheimer’s. Why didn’t it tell the world?

    https://www.washingtonpost.com/business/economy/pfizer-had-clues-its-blockbuster-drug-could-prevent-alzheimers-why-didnt-it-tell-the-world/2019/06/04/9092e08a-7a61-11e9-8bb7-0fc796cf2ec0_story.html?utm_term=.1418de0736c6 Not ME/CFS, but provides an overview of the difficulty of new drug...
  3. J

    Harvard ME/CFS Collaboration Symposium June 8th 2019

    Anybody going to this? Apparently there is a waiting list to attend now. I can't find any agenda for this 3 hour event.
  4. J

    Everyone Knows Money Influences Politics … Except Scientists (CFS mention)

    https://fivethirtyeight.com/features/everyone-knows-money-influences-politics-except-scientists/ CFS mentioned here... not about CFS tho
  5. J

    Stanford Community Symposium 2018: Phair, Metabolic traps, Tryptophan trap

    On PR Phair mentions that he has submitted a manuscript on the metabolic trap to a journal. If this is accepted, it might provide a starting point for pharma companies to begin some type of drug discovery. On the more pessimistic side, I’m pretty sure Phair et al. don’t really have any idea...
  6. J

    A nanoelectronics-blood-based diagnostic biomarker for ME/CFS (2019) Esfandyarpour, Davis et al

    One suggestion-- If folks still have questions on the methods of this paper, a suggestion would be to see if @JaimeS might be able to send Esfandyarpour an email to see if he would be willing to answer questions on this forum. Suggested Jaime rather than doing it myself because I assume that...
  7. J

    Do ME symptoms fit with the faulty energy metabolism hypothesis?

    @Jonathan Edwards So in case some weren't able or willing to access the above cited PR thread: Phair says that every time there is a good case for a dysfunction in energy production, there is an offsetting case for there being no dysfunction. He mentions that Paul Fisher's talk in Australia...
  8. J

    Living With Lyme Disease, Stronger With Love

    Living With Lyme Disease, Stronger With Love Brian Nicholson thought Brooke Geahan was the most beautiful woman he had ever met. He also knew that she was very ill. https://www.nytimes.com/2019/05/24/fashion/24VOWS-Sonoma.html 1) No such thing as chronic Lyme, correct? 2) She got better from...
  9. J

    An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals

    here is a short summary of this research. https://www.fightaging.org/archives/2019/05/anethole-trithione-is-a-mitochondrial-ros-blocker/
  10. J

    The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

    thanks. Is a lot or a little? (from above study) The experimental group: Patients were asked to take 1 g oral capsule containing EPO every 12 hours for 3 months in addition to the standard treatment for their disease.
  11. J

    IiMER International Conference Week London 2019

    I assume that there is no livestream of the conference? Also if anyone from here is going to the conference, would really appreciate it if anyone could ask Dr. Fluge when he anticipates submitting the cyclophosphamide manuscript for review (or maybe it is under review?). Thank you.
  12. J

    The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

    https://www.s4me.info/threads/erythrocyte-deformability-as-a-potential-biomarker-for-chronic-fatigue-syndrome-davis-et-al-2018.6938/page-6#post-127447 Looks like @alex3619 is not a fan
  13. J

    The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003444/ Fig. 5 looks pretty good. Anybody try this?
  14. J

    Colchicine

    Thanks for report.
  15. J

    Jen Brea: My ME is in remission

    What happens after surgery? Does your head pop out more from neck/shoulders? Can you turn your head like a normal person? Like an owl? What are the potential complications?
  16. J

    Do ME symptoms fit with the faulty energy metabolism hypothesis?

    Should be OK to look.....Voyeurism is permitted.
  17. J

    Do ME symptoms fit with the faulty energy metabolism hypothesis?

    @Jonathan Edwards It looks like Robert Phair agrees with you that there is no compelling evidence for dysfunctional energy production in ME/CFS. Here https://forums.phoenixrising.me/threads/the-ido-metabolic-trap-guy.62727/page-15
  18. J

    Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms

    Summary Author doesn't believe existing explanations (which are admittedly unusual) for observed symptoms (fatigue, brain fog, etc.). Therefore it is likely "functional disorder", which I think means "it is something, but we don't know what it is". Only interview people who agree with FD...
  19. J

    Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms

    Merged thread https://www.nytimes.com/interactive/2019/05/15/magazine/diplomat-disorder.html?action=click&module=Editors Picks&pgtype=Homepage An “unknown energy source” has been blamed for debilitating symptoms suffered by Americans posted in Cuba. The real cause may be more surprising...
  20. J

    An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals

    Yeah anethole is different from anethole trithione— the former doesn’t have the three sulfur molecules.
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