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The ME-NOME Project. (?)

Though they are quite expensive, there are water-cooled/heated mattress pads. One I've seen is called the "Chilipad." An external unit heats/cools water that runs through tubing contained in a fabric "pad." I'm pretty sure you lie on top of the pad rather than under it, but it might make the...

One of the potentially stupid things I did in the wake of the severe upper respiratory infection I had (which began about three weeks before onset) was to resume my practice going for long bike rides in the evening, which typically left me drenched in sweat. I only did this once or twice during...

Yeah - I fell ill in the US in 1983 and my doctors made no mention of "myalgic encephalomyelitis," even though my neurologist's summary contained the words "myalgia" and "possible encephalitis." I was left with the idea I had a poorly defined post-infectious condition which, hopefully, would...

I may be wrong, but the Journal of the American Medical Association (published weekly) seems to be mainly aimed at physicians, some of whom would be researchers, but many of whom would not. I take Dr. Komaroff's article as intended primarily for physicians who see patients, and that its overall...

This is bad news for the diplomats. It can only mean that their symptoms are psychogenic.

I was just referencing what other people on the board have said about the NEJM. I was surprised when I read it. I don't know if it's an official stance of the NEJM or just a de facto policy.

I think you may mean "epidemic neuromyasthenia," not "epidemic neurasthenia." "Neurasthenia" was a 19th century diagnosis of people who were deemed to have been afflicted with the stresses of modern life in a post-industrial, urbanized world. Its popularity as a diagnosis had dwindled to almost...

It may depend on one's definition of "described." The Ramsay "definition" lists numerous symptoms that he observed in the 1955 outbreak. The 1988 Holmes criteria attempts to create a threshold of symptoms beyond which a patient is deemed to have "CFS." Komaroff has certainly said that choosing...

The sub-headline and photo caption in the Guardian article incorrectly refers to Marianne Williamson as the "Democratic Nominee." She's a candidate for the Democratic nomination, not the nominee. All you have to do to be a candidate is to meet the citizenship, age and residency requirements and...

It was interesting to see Dr. Davis go over the "metabolic trap" again. If I have this right... IDO1 converts L-Tryptophan into L-Kynurenine in the cell. If there is too much L-Tryptophan in the cell, IDO1 gradually shuts down and the conversion ceases. If nothing intervenes, L-Tryptophan...

Fortunately, CBT research has shown that there's overwhelming evidence that a single course of CBT can keep researchers from exaggerating the "evidence-base" of CBT.

FWIW, there seems to be a thing called a "vestibular migraine" which can cause balance problems, tinnitus and some other symptoms, without necessarily producing a headache. Whether this is related to true migraine, or is more of a metaphor, I'm not sure. One website says that symptoms occur when...

I've had both c) and d), so I'm not sure which to vote for.

And yet, the band plays on...

The paper from which this citation was gleaned also says: The same paper says: The claim that "25% and 50%–75% of patients have a current or a lifetime history of major depression, respectively" is apparently an amalgam of 5 different citations in a paper by Buchwald (so, in the Watanabe...

Come to think of it, when I had dyshidrosis as a teen, some of the smaller blisters would often merge into a larger blister. The larger surface of the resulting blister was thin enough to be transparent. Since they were filled with clear liquid, you could use a magnifying glass to look inside...

I call for the immediate release of this clearly suppressed cytokine data! :) [By my count, the text of the PACE Trial contains the word "cytokine" precisely ZERO times.]

They may not have been trained to react to the absence of the sound created by the gap, but rather to react to total silence - something they couldn't experience with tinnitus. I did wonder, though, how they could be certain that the mice weren't simply deaf.

I think they attempt to induce tinnitus by exposing the mouse to a loud sound. Subsequently, they use a "gap detection test," where another sound is played which has a "gap of silence" in it. The mice have been trained to react to the gap of silence in some way (e.g. they stop licking water)...