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  1. Forbin

    Brain throwing a party before bed - not pleasant

    I realize that you're not talking about dreaming, but when I googled "rapid images dreaming" the first thing that came up was a forum for lucid dreamers where some people were reporting this kind of thing. http://ld4all.com/forum/viewtopic.php?t=37401 It's interesting that the first post is by...
  2. Forbin

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    If there "something in the blood," I wonder if that might be related to why patients feel better following an infusion - i.e. the blood becomes more dilute, possibly reducing the concentration of "x" to below some kind of symptomatic threshold. Similarly, if patients have low blood volume, then...
  3. Forbin

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    I didn't have trouble live-streaming this, but that may be because I was watching it at a relatively low bit-rate. In my experience, it's fairly unusual to have multiple bit-rate streams available during a "livestream." This suggests that they have multiple processors/computers generating each...
  4. Forbin

    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    I only had the opportunity to see a few of the presentations, but I was really impressed by Dr. Systrom's talk. It struck me as a real tour de force of how to effectively convey a lot of complex information in a short time.
  5. Forbin

    Brain throwing a party before bed - not pleasant

    I've experienced something similar once or twice, though, for me, it seemed to be more of a dream. Basically, my mind was just jumping from one unrelated image/thought to another every second or so. In my case, this first happened the evening I tried taking L-tryptophan for the first (and only)...
  6. Forbin

    ME from stress ?

    I think that stress can reactivate some dormant viruses. It seems to be true of the herpes simplex virus which can remain dormant among neurons. This article explains how it can occur. Apparently, corticosteroids, like cortisol, can open a pathway that allows the viral DNA to "unwind" enough to...
  7. Forbin

    A Timely Multidisciplinary Update on ME/CFS, 2019, Theoharides

    Well, he's out of Boston, and I'd be willing to guess that very few doctors in the US ever heard of ME before they heard of CFS. I became ill in the early 1980's and no doctor (not even my neurologist) ever mentioned "ME," just a vague notion of a post-infectious syndrome. "CFS," of course, was...
  8. Forbin

    B-Lymphocyte Depletion in Patients With ME/cfs: A Randomized, Double-Blind, Placebo-Controlled Trial (2019) Fluge et al

    That makes sense. I'd assume that a similar percentage in the rituximab group (~19%) would have adverse effects for the same reason, leaving 7% (or more, due to overlap) to other causes.
  9. Forbin

    B-Lymphocyte Depletion in Patients With ME/cfs: A Randomized, Double-Blind, Placebo-Controlled Trial (2019) Fluge et al

    I'm curious about the 18.9% in the placebo group that had "serious adverse events." Would this be the so-called "nocebo" effect, and can that actually produce serious adverse events? Or might these events have been part of the disease process itself and unrelated to the study?
  10. Forbin

    Data/info request from Robert Phair for Relapse/Remit people

    There were a few times, maybe 4 or 5 times, in the first couple of years of illness that my otherwise constant dizziness either let up entirely or was greatly reduced. Unfortunately, this never lasted for more than 15-30 minutes. I recall feeling generally "better" during these brief periods...
  11. Forbin

    A Timely Multidisciplinary Update on ME/CFS, 2019, Theoharides

    Reading articles like this, which principally equate the disease with "fatigue," makes me wonder if we might not be better off if the disease was called something like "Persistent Physiologic Malaise Syndrome," or even "Persistent Somatic Malaise Syndrome." Not that "malaise" doesn't have its...
  12. Forbin

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    Dr. Nath understandably does not want to discuss any findings yet. My impression is that they don't even want to analyze the data at this stage. Still, I'd love to ask him, "So, given what you've seen so far, what do you think of the deconditioning hypothesis?"
  13. Forbin

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    Now that I look at it again, it is not completely clear that they are screening out everyone with an autoimmune disorder, but they might be. I wonder how stringent they are in this regard. For instance, scalp psoriasis is no doubt autoimmune in nature, but it can be relatively mild in some...
  14. Forbin

    Brian Hughes - If you spend 20 years gaslighting your patients, perhaps you should think twice before accusing *them* of trolling *you*

    It couldn't be that people with a primarily physical illness have a stronger belief in a solely physical cause than people who do not have a primarily physical illness, and that the real problem is that the case definition being used simply can't differentiate between the two groups... could it...
  15. Forbin

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    I do wonder about the exclusion of all autoimmune disorders, though. I believe Dr. Hanson and others have found similarities in the makeup of the mircobiome between some ME/CFS patients and patients with Crohn's disease and chronic ulcerative colitis, both of which are believed to be autoimmune...
  16. Forbin

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    Wait... that can't be right. We have it on the highest authority that...
  17. Forbin

    Decreased Expression of the CD57 Molecule in T Lymphocytes of Patients with Chronic Fatigue Syndrome, 2019, Espinosa and Urra

    Yeah, I remember people calling it "The Chronic Fatigue Syndrome" around 1987. I have a feeling it may have been due to the subconscious influence of the 1979 movie "The China Syndrome." The Chernobyl disaster happened in 1986, so the 1979 movie was probably being referenced a lot around that time.
  18. Forbin

    Michael Sharpe on Radio 4 Today / Tom Feilden BBC (18th march 2019)

    It's interesting to contrast his bristling at criticism with what Ron Davis said at the start of his presentation on the first day that he talked in Australia. I'm paraphrasing here because I failed to record it, but the gist was that it is the job of a scientist to get up everyday and try to...
  19. Forbin

    Michael Sharpe on Radio 4 Today / Tom Feilden BBC (18th march 2019)

    Since he uses the word "campaign" 8 times in the course of one short interview, I wonder in how many other public forums he will vigorously speak out against... uh, "campaigning."
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