Search results for query: pace trial

It would be interesting if someone did a study like this: 1. Have participants with ME/CFS. (Could be interesting with other groups also.) 2. Randomise in two groups. 3. Show Group A videos about people with severe ME/CFS. 4. Show Group B videos about healthy people doing vigorous...

is this a windup? Haven't you heard of the PACE trial?

...important topics discussed at length in threads started years before I fell ill. Scientific results, but also historic context. The PACE trial, Cochrane reviews, concrete cases of neglect and maltreatment, the Science Media Centre, common issues with methodology, common arguments and...

In addition, the treatment effects were not clinically significant from what I can see. They defined the minimally clinically important difference (MCID) for the primary outcome (the FAS) as a change of 3 points. The FAS benefits compared to no treatment were : -1.49 points [95% CI –2·92 to...

With an open trial and a subjective outcome measures I do not think you can say that. Graham's PACE trial video points out why. Given all the contextual factors I think the result is absolutely what one would expect if none of the treatments had any specific useful action.

It might be worth making the point that the PACE trial showed that existing psychobehavioural interventions and management strategies do not have a significant effect on ability to work - Wilshire, C.E., Kindlon, T., Courtney, R. et al. Rethinking the treatment of chronic fatigue syndrome—a...

The request was this, I think https://www.change.org/p/me-cfs-changing-the-definition

Good luck to anyone that benefits but the reported success rate in such interventions is part of the therapy as is any proclaimed "understanding". Paper seems to assert that no relevant biological findings are out there.

...The Switch has a self-proclaimed success rate of more than 80%. However, Jessica Bavinton, the physiotherapist that co-wrote the PACE Trial GET manuals, says that their vitality360 rehabilitation programmes achieve 86% of return-to-work goals. I’m lost, where should I spend my money? ETA...

To start with some natural recent ones: DecodeME and Incidence age is bimodal for ME/CFS I'm not sure what exactly the results of this paper would mean (if they replicate), but @DMissa's work is so careful and thought out it's always going to be valuable: Multi-omics identifies lipid...

This is literally making work a health outcome. It sounds a lot like training people into work and never mind the consequences, check out the employment figures! "86% of return-to-work goals achieved through our rehabilitation programmes" Whose goals? Government or claimant? That fact that...

Thread for article in FAIR: Media Won’t Stop Psychologizing Long Covid

How our team can help you. Rehabilitation programmes for people with persistent pain and fatigue. Have you had to stop doing the things that you used to enjoy? Can you barely think straight? Are you having trouble sustaining work? Are you struggling with persistent pain? Are you debilitated by...

Disability Impact training via Access to Work - A government-funded scheme Go to, https://www.vitality360.co.uk/disability-impact-training Jessica Bavinton is the physiotherapist that co-wrote the PACE Trial GET manuals. People have been referred to her services by insurance companies as I recall.

If only the venerable George Davey Smith had been able to apply the same rigour to his assessment of the PACE trial...

Was it this one? J Psychosom Res 2020 Aug:135:110154. doi: 10.1016/j.jpsychores.2020.110154. Epub 2020 May 23. Patterns of daytime physical activity in patients with chronic fatigue syndrome E King , M Beynon T Chalder, M Sharpe, P D White PMID: 32504895 DOI: 10.1016/j.jpsychores.2020.110154

I am not sure that a faulty power calculation would alter the validity of results. It would call into question the ethics of setting up the trial but the statistical significance of the results does not depend on someone judging how likely they are to get a significant result in advance? The...

https://s4me.info/threads/centre-for-welfare-reform-in-the-expectation-of-recovery.1823/

...It was published in 2016, but still has relevance to both the scientific research of the biopsychosocial approach, especially the PACE trial, and to how people with ME/CFS and long Covid are viewed and treated by government welfare departments and the insurance industry. I think it's...

The PACE trial investigators also fiddled with the registration to remove the original primary outcomes. From an earlier version: From the version last edited in 2015: