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Type I errors (falsely reported an effect when it isn't there), also known as a false positive. Type II errors (failing to report an effect that is genuinely there), also known as a false negative.

If you remember the good old days, you weren't there.

Yes, I think there is more mileage in this yet, because it exposes both deliberate misrepresentation by the authors, and poor quality peer-reviewing and editorial oversight. Plus it is also clear cut.

Pure arse covering, just in case it turns out to be true. If it wasn't about ME, then why did they use the London ME criteria for sub-grouping? Sailing? Another trick is to change the oil out for a more viscous one, which helps keep the pressure up, without fixing any problems.

One good place to start is a proper assessment of the PEM phenomena, and the true nature and extent of the alleged deconditioning. Even if that does not provide any immediate clues it will help frame future progress, and firmly lay to rest any misuse or denial of PEM and deconditioning by the...

Huge thanks to everybody in the patient, medical, and parliamentary communities who made this debate possible and made sure it was well informed. Likes for all! :thumbup::hug::) If we can break the back of this monster in the UK, from whence it was hatched, then it is basically over. Then we...

Lord Winston, for example, who should have known better, given his previous career was in medicine. Agree. We have to adapt to the phase the argument is at in the political sphere.

I can feel a crowd funding coming on for the first case.

Some good, some not so good: “...characterised by extreme and debilitating fatigue, particularly after exertion.” Doesn’t really capture it. Fatigue is not the primary nor characterising symptom. It may be a primary symptom, along with pain, cognitive, sleep, hemodynamics. “Clinically, ME/CFS...

Being positive doesn't exclude being mightily pissed off. Anger is a powerful motivator.

Oops. :oops: Zimbardo dined out on that study long and hard.

A good, if very disturbing read. There really is something profoundly rotten at the core of UK medicine. How many more lives are going to be destroyed and lost before this insanity is stopped?

Exactly. He is playing games with words, and not playing very well either. Only communists, perverts, and those in denial of mental illness dress to left. All right thinking people dress to, well, the right. Another is that the more seriously ill are more likely to join self-help groups. Yet...

Oh, he knows. Just can't face the consequences of admitting it.

Nice work, @Sly Saint. Catch them out with their own words, the ones they voluntarily placed on the formal record multiple times, over decades. Collate and cross-reference, and ye shall be rewarded. --------------------- Absolutely. Their refusal to stop the use of PACE to justify it...

Sadly, and quite apart from libel laws, that is the smart position for them to take at this point. They cannot be seen to prejudge it, which I agree with. I would do the same in their position at this point. The media have a lot to answer for over this whole shit show, but now is not the time...

Might be an interesting study to look at how many times in medicine a single poor quality (or at least a far from definitive) study somehow ends up being uncritically accepted and endlessly cited as the one that established a field/approach/idea/treatment. The original paper on placebo for...

We can help by spreading the message.

If sustained at follow-up.

All the best, Joan, and thanks for wading through that soul destroying nightmare. They have their place. I just wish they knew what it was and stuck to it.