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Isn't it SS-31?

Or indolepropionate?

I thought Ron Davis had been saying (previously) that it wasn't a virus. Has he changed his mind?

Should that be indopropionate?

Absolutely not in my experience. All the days have blurred into one and I could not tell you whether something happened yesterday or last week.

Interestingly it made my POTS slightly better. Although ginger (also a potential vasodilator) made my Pots worse.

Oh, also the beneficial effect for me comes several hours after taking the curcumin.

Yes, here are a couple of reviews: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/

Ah, I must have gotten my researchers mixed up there. I take turmeric and curcumin in a capsule, so they don't taste of anything to me. It is not just a popular belief, various studies have found effects of curcumin in a few different illnesses.

On your point re microglial activation. Didn't Jarred Younger find this in ME? On your point re ibuprofen and cytokines and inflammation. That is interesting. Do you know whether turmeric or curcumin could have a similar effect? I am absolutely certain that for me personally this hugely...

What do you think would be useful measures to measure with and without cognitive PEM? Interesting suggestion re sleep deprivation... personally, having experienced both sleep deprivation and ME (both separately and together) it doesn't feel to me like a related thing... but feelings can be...

I think for me... a small to medium cognitive or physical overexertion will only produce cognitive or physical PEM respectively, but a really large overexertion will result in lots of different PEM symptoms.

These articles are physical exercise. I know that studies have been done on PEM from physical exertion. I want studies to be done on PEM from cognitive exertion.

Just curious how people's experience compares with mine.

Some reflections from me on this topic, as I am currently experiencing some worsening as a result of PEM. It (my current worse-than-usual cognitive state) doesn't feel like a reduction in energy production. It feels like there's some kind of blockage in my brain. So I wonder whether...

As I've said before, this is the thing which most completely baffles me regarding this disease. What is it that goes on in my brain when I cognitively overexert (even by a small amount) that results in worsened cognition for a long time?! And if cognitively overexerting by a large amount, then...

A study I want someone to do: (as far as I know, a study has not been done on this) Group of patients. First measurement at a time when they are not in PEM Get them to overexert themselves cognitively Second measurement immediately after the exertion Third measurement during PEM time...

Oh mine isn't like blood at all

I don't know whether mine is metallic. I don't know why people describe tastes as metallic. I don't eat metal and I don't think anyone else does either. (This might be my autism literal thinking at work?)

Why didn't they look for other trustees to replace the ones who couldn't do it?