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  1. Sean

    PEM discussion thread - post-exertional malaise

    If we ever get a clear biomarker profile for ME, I think it quite likely it will be a much more common problem than we currently believe. Good point.
  2. Sean

    Neurasthenia: Unexplained Tiredness: Exploring your mind blog: Spain based.

    Our objective is to spread valuable information and provide key tools to improve human relationships and thus promote both individual and collective well-being. The Devil is in the details.
  3. Sean

    Cognitive behavioural therapy for adults with dissociative seizures (CODES): a ... multicentre, randomised controlled trial (2020) Goldstein, Chalder

    Should be banned outright. A core condition of formal peer-reviewed publication must be that the data is made permanently available to the public (with appropriate anonymity safeguards). The cost of doing so is trivial these days. No excuses. IIRC, PACE has a compulsory data retention period of...
  4. Sean

    Edinburgh Long Covid Study, led by Alan Carson

    Who wants to predict the findings of this study?
  5. Sean

    News from Australia

    We must do something. This is something. Let's do this thing.
  6. Sean

    Editorial: A research agenda for post-COVID-19 fatigue, 2022, Wessely, Knoop et al

    I hope you are right. I agree that we certainly have made major critical gains in recent years, and momentum is with us of late. But any celebration is a little premature. The BPS club is not going down without the most ferocious of fights to cling onto their ill-gotten power and glory and income.
  7. Sean

    In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway..., 2022, Maes et al

    physiosomatic symptoms (formerly named psychosomatic) So is this just a rebrand? Or is it a genuine attempt to move away from the psychogenic presumption?
  8. Sean

    Fear conditioning as a pathogenic mechanism in the postural tachycardia syndrome, Norcliffe-Kaufmann et al, 2022

    Interestingly, Wessely et al, and separately Bazelmans et al, showed in the mid-90s that hyperventilation is not an issue in ME (CFS). There was no association between level of functional impairment and degree of hyperventilation. There is only a weak association between hyperventilation and...
  9. Sean

    Your Book Review: Exhaustion Finalist #13 in the Book Review Contest

    I don't recognise this group of people.
  10. Sean

    Multidisciplinary rehabilitation treatment is not effective for ME/CFS: A review of the FatiGo trial, 2018, Vink & Vink-Niese

    Yes, those very weak numbers are the best possible case scenario. Which is an appalling fact.
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