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  1. Kiwipom

    Preprint Wearable heart rate variability monitoring identifies autonomic dysfunction and thresholds for post-exertional malaise in Long COVID, 2025, Ruijgt+

    n=1 here of using HRV to guide pacing and avoid PEM. especially overnight HRV. Clear association with reduced HRV and need for better pacing and avoiding a crash. My Garmin has been keeping me well, without it I'd be PEMtastic. I also use the body battery function which incorporates HRV and HR...
  2. Kiwipom

    Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation, 2023, Salvucci et al

    And such small numbers. Easy to do better here with a prospective RCT and more participants
  3. Kiwipom

    New Alcohol Sensitivity in Patients With Post-acute Sequelae of SARS-CoV-2 PASC: A Case Series, 2023, Eastin, Bonila et al.

    I'd fully expect alcohol intolerance in long COVID & ME-CFS due to the known effects of alcohol on GABA receptors and its significant vasodilator, potential histaminergic type effects +/- hepatic metabolism. Alcohol causes an immediate noticeable drop in HRV- this well known to well, fully...
  4. Kiwipom

    Association between COVID-19 and outstanding academic performance at a Spanish university, 2023, Amer et al.

    Association vs causation...Did the more sociable students who got COVID do too much partying and not enough staying at home studying?
  5. Kiwipom

    Autonomic dysfunction and exercise intolerance in post-COVID-19 - An as yet underestimated organ system?

    Psychological effort? For exercise? This is ridiculous and doesn't make any pathophysiological sense. PEM experienced after standing upright or overdoing ADL is not psychological in origin. I can safely say that my psychological capacity frustratingly and consistently always far exceeds my...
  6. Kiwipom

    Dysautonomia, but Not Cardiac Dysfunction, Is Common in a Cohort of Individuals with Long COVID, 2023, Tabacof, Putrino et al.

    Flat/collapsible IVC on ultrasound is an indicator of hypovolaemia, but assume it wouldn't be particularly indicative here unless it was either very full or very flat? TTE would be a more accurate measurement for preload and RA volume, but I can't see measurements in the paper's results...
  7. Kiwipom

    Autonomic dysregulation in long-term patients suffering from Post-COVID-19 Syndrome assessed by heart rate variability, 2023, Mooren et al

    These findings are reflected in my HRV readings. I'd like to see a longer study of HRV trends rather than a one day snap shot. I've found HRV has helped me predict whether I'm heading towards better or worse and can then pace better preemptively
  8. Kiwipom

    “Your Blood is Black”: My ME/CFS Experience with HELP Apheresis in Germany

    I definitely have noticed something very similar wrt poor peripheral blood flow- cold purple/grey toes and fingers, hands and feet on bad days and most mornings still. Prolonged capillary refill time, ie very sluggish circulation, low measured oxygen saturations using the usual infrared finger...
  9. Kiwipom

    “Your Blood is Black”: My ME/CFS Experience with HELP Apheresis in Germany

    I It may be that you were fluid deplete, as this would cause reduced CSF volume. LPs take ages in this case and yes they'd try to do it with you sitting up. Long covid seems to cause weird fluid shifts despite adequate hydration, causing intravascular hypovolaemia which may well cause a...
  10. Kiwipom

    Impaired parasympathetic function in long-COVID postural orthostatic tachycardia syndrome – a case-control study, 2023, Stefano Rigo et al

    I had a brief look at this- full text is available online and it seems like a pretty decent study. A lot more research to be done in this area, but a good start here. There does appear to be significant parasympathetic deregulation and inappropriately unbalanced/unopposed sympathetic drive in...
  11. Kiwipom

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication, 2023, Montezano et al.

    Painful to say in public, as I have always been very pro vaccine, but n=1 for Pfizer spike protein here
  12. Kiwipom

    Characteristics and Treatment of Exercise Intolerance in Patients With Long COVID, 2023, Edward et al

    T This is very contradictory, it doesn't make any sense. Such bias towards graded exercise even when it's clearly contraindicated. Just be more motivated, tell yourself you are OK. I can't find an eye rolling Me too, I went from 1h30 half marathons to unable to walk overnight. Must have been...
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