The way I personally interpret pacing is closer to pacing your energy during physical effort (e.g. a race). There's a very flexible/adaptive nature to that which largely depends on feeling and prior experience. Which does seem to fit with ME/CFS and avoiding PEM. But I can see the problems...
Interesting theory! So basically immune cells are fighting each other in the lymphatic system and this triggers something similar to sickness behaviour (which normally only occurs when immune cells are fighting an infection).
@Jonathan Edwards if I may:
1. That does make me wonder: why do other...
@jnmaciuch @Jonathan Edwards Given that DecodeME has started pointing us more towards the brain and Jarred's lab focusses on the brain in ME/CFS, do we have any leads that would be more interesting for him to pursue? Considering the disappointment here with his current endeavours..
From AFME:
Which would be quite a lot to raise through crowdfunding.
I think our biggest hope would be government funding. The DecodeME results obviously are supportive of this. But I have no idea how that works in the UK. Else it would be nice if AFME, OMF etc. would launch a huge...
I wonder what these recommendations are based on.
Are their negative effects with long-term use?
What happens if you take it while having an autoimmune disorder, a seizure disorder or depression?
My mom has struggled with horrible migraines for most of her life. Tried every possible treatment. Two years ago she got referred to a neurologist with a lot of expertise on migraines. He got her to try the newest drug class: mAbs that inhibit CGRP. She hasn't had a single episode since, it's...
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