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  1. Sean

    ME/CFS classed as 'Acquired Neurodivergence' by some DWP Access To Work Training Guides

    'ACT assumes that Obvious flaw is obvious.
  2. Sean

    The Sick Times: A journalist-founded website chronicling the Long Covid crisis

    Medicine demands physicians be invulnerable, trained to push through exhaustion, As I have noted before, medicine's great blind spot is in dealing with conditions that feature a major reduction in stamina. From day one of med school, through to at least a decade or so post graduation, the...
  3. Sean

    The Paradox of Modern Medicine—The Atlantic

    It is a good article, that touches on many of the points we have been making for decades. But I also agree with @rvallee about the problems with the perversion of evidence-based medicine, having all the form but none of the content, and that being used to stifle dissent and criticism. Would...
  4. Sean

    USA: News from Solve ME

    I would expect such a phenomenon to be lethal, and within minutes. If they had said a significant reduction in cellular energy production, that would be at least plausible as an initial hypothesis. But a complete collapse is not even vaguely plausible.
  5. Sean

    USA: News from Solve ME

    a complete collapse of cellular energy production, News to me.
  6. Sean

    Problems arising for pwME from additional diagnoses of MCAS, hEDS and POTS. Advocacy discussion.

    Lack of evidence and logic are fertile grounds for fantasists and grifters of all persuasions.
  7. Sean

    Placebo effects improve sickness symptoms + drug efficacy during systemic inflammation: randomized controlled trial in human experimental endotoxemia

    Indeed. If the placebo effect is so powerful why have they not employed it effectively? Where are the substantial practical benefits of it?
  8. Sean

    The ME Association Clinical Assessment Toolkit (ME-CAT) and app (autonom-e)

    Point taken about the dangers of trying to mindlessly quantify things. I just meant it as the principle we should be aiming to quantify things that can be meaningfully quantified. A core part of which is figuring out what those things are, and what they are not. Endless rounds of self-report...
  9. Sean

    Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank, 2024, Huang et al

    1. Not up to following this debate. That said: 2. Comorbidities do have to be factored in somehow. Almost all humans have them, and getting a clean comorbidity-free sample from any group is difficult at the best of times, let alone from a group who have been very sick for many years, some for...
  10. Sean

    Cardiopulmonary Exercise Test Results Do Not Change Over Two Sequential Days in Patients with Chronic Fatigue Syndrome, 2026, Mancini, Natelson et al

    They are really struggling to let go of the deconditioning myth. Understandable, as it is a central assumption for psycho-behavioural paradigm. But that is no excuse. If it is wrong – and it is – then out it goes. We would probably get much more informative results if they kept up the daily...
  11. Sean

    Teaching about persistent physical symptoms with the aid of a television show: medical undergraduate students’ perceptions 2026 de Souza et al

    Innovative pedagogical approaches may help address these gaps. Funny way to spell ideological propaganda. The flood of papers in recent years focused on how to better market their 'product' is revealing. If their product was good they would not need to flog it so hard, and invent excuses as to...
  12. Sean

    Guided versus unguided internet-administered emotional awareness and expression therapy (I-EAET) for patients with [PPS] 2026 Maroti et al

    Yes, they understand it enough to rig it in their favour. They are also quick to point out the methodological weaknesses in biomed studies, thus demonstrating that they know what they are doing.
  13. Sean

    inews.co.uk: "At 35, I was bedbound with ME – this is how I got my life back"

    ‘Finally Awakened’ comes out on Amazon on 21 April Because of course she has something to sell. :cautious:
  14. Sean

    Recovery from chronic fatigue syndrome: a reflexive thematic analysis of experiences of people before, during and after treatment, 2025, Chalder+

    Selective use of diagnostic criteria, (including arbitrary modifications to them, thus making the results hard to compare with other studies - see PACE). Lack of long-term follow-up.
  15. Sean

    The ME Association Clinical Assessment Toolkit (ME-CAT) and app (autonom-e)

    Well, the identify and quantify bits are okay, the 'understand' bit is worrying.
  16. Sean

    The ME Association Clinical Assessment Toolkit (ME-CAT) and app (autonom-e)

    The aim is to identify, understand and quantify people’s symptoms and disabilities. No in principle problem with this bit, though it is hardly novel or insightful. It will support goal setting, treatment planning, and monitor changes. Massive problem with the first two of those. Goal setting...
  17. Sean

    Why does FND mainly affect women? A consideration of gender imbalance in neuropsychiatric disease, 2026, Bradlow et al

    "Misdiagnoses of FND are rare and the effects are likely minimal" the authors say. :rolleyes:
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