2021

Preprint Abstract Purpose: People living with long COVID describe a high symptom burden, and a more detailed assessment of chronic fatigue and post-exertional malaise (PEM) may inform the development of rehabilitation recommendations. The aims of this study were to use validated questionnaires...

Abstract Aims: Post-exertional malaise (PEM) is poorly understood in Gulf War Illness (GWI). Exercise challenges have emerged as stimuli to study PEM; however, little attention has been paid to unique cardiorespiratory and perceptual responses during exercise. This study tested whether select...

Highlights • Chronic inflammation can be caused by organelle (e.g., mitochondria) malfunction. • Dysfunctional mitochondria release DAMPs that trigger inflammation through PRRs. • Salivary cells’ mitochondria show ultrastructural alterations in Sjögren’s syndrome. • Endoplasmic reticulum...

Abstract The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, is leading to unknown and unusual health conditions that are challenging to manage. Post-COVID-19 syndrome is one of those challenges, having become increasingly common...

Abstract During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, neurological symptoms increasingly moved into the focus of interest. In this prospective cohort study, we assessed neurological and cognitive symptoms in hospitalized coronavirus disease-19 (COVID-19)...

Funded study in progress. Abstract: Background: Paediatric Chronic Fatigue Syndrome or Myalgic Encaphalistis (CFS/ME) is disabling and relatively common (1-2% of teenagers). We need to improve treatment but need a well developed Patient Reported Outcome Measure (PROM) to do this. Clinical...

A person-centred test of multidimensional perfectionism and health in people with chronic fatigue syndrome versus healthy controls Fuschia M. Sirois, Loren Toussaint, Jameson K. Hirsch, Niko Kohls, Martin Offenbacher Abstract: Theory and evidence suggests that person-centred models may be...

Highlights • FND patients have high depression and alexithymia. • The avoidance pattern of attachment is associated with mood disorders and alexithymia. • Sex, anxiety and alexithymia were significantly associated with functional seizures. Abstract Objective The contribution of psychological...

Trends in Molecular Medicine Insights from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome May Help Unravel the Pathogenesis of Post-Acute COVID-19 Syndrome Anthony L. Komaroff, W. Ian Lipkin Highlights • In some people, the aftermath of acute COVID-19 is a lingering illness with fatigue...

The spin on this is quite shocking: https://www.cambridge.org/core/journals/psychological-medicine/article/efficacy-of-therapistdelivered-transdiagnostic-cbt-for-patients-with-persistent-physical-symptoms-in-secondary-care-a-randomised-controlled-trial/CEDD9B7597902C283BBB7CA7B43A81C7 Efficacy...

Abstract Post-exertional malaise (PEM), the key feature of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is characterized by baseline symptom exacerbation after exposure to a stressor, and some patients can experience new or non-typical symptoms. We hypothesized that new or...

The paper comparing results in female CF And ME/CFS patients is posted later on the thread here and had its own thread that is now closed and the discussions merged Comparing Idiopathic Chronic Fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Males: Response to Two-Day...

Abstract In a previous study using mobile-health technology (mHealth), we reported a robust association between chronic fatigue symptoms and heart rate variability (HRV) in female patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This study explores HRV analysis as an...

Abstract Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system function, and severity of...

Highlights The overall quality of medical research remains poor, despite longstanding criticisms. The scientific enterprise is business-like and consistently undervalues its own backbone, methodology. Despite great initiatives to improve research quality, progress is modest. Top-down action...

Faith Newton Abstract Children with ME/CFS who are severely ill are bedbound and homebound, and oftentimes also wheelchair-dependent. Very seriously affected children are often too sick for doctor’s office visits, let alone school attendance. The most recent data estimate that 2–5% of children...

Full title: Elements of Suffering in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Experience of Loss, Grief, Stigma, and Trauma in the Severely and Very Severely Affected Abstract People who are severely and very severely affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome...

Chronic pain syndromes in childhood, 2021, Schechter (Oxford Textbook of Pediatric Pain) Written from a biopsychosocial perspective and looks annoying. I seem to be able to see all or nearly all of it here...

https://www.sciencedirect.com/science/article/abs/pii/S0022399921001781 Journal of Psychosomatic Research Available online 28 May 2021, 110533 In Press, Journal Pre-proof Adverse outcomes in trials of graded exercise therapy for adult patients with chronic fatigue syndrome P.D.White a...

From: Dr. Marc-Alexander Fluks Source: Analytica Chimica Acta Preprint Date: May 25, 2021 URL: https://www.sciencedirect.com/science/article/abs/pii/S0003267021005043 Broadband electrical impedance as a novel characterization of oxidative stress in single L6 skeletal muscle cells...