Highlights
• Guided graded exercise self-help (GES) can lead to sustained improvement in patients with chronic fatigue syndrome.
• There was no evidence of greater harm after GES compared to specialist medical care at long-term follow-up.
• The study showed that GES was probably...
Is your age within the range of 18 to 35?
Do you identify as a disabled person?
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Do you have experience or are interested in disability activism and disability politics?
If you answered yes to these questions then please consider taking part in this...
Expert Forum on secondary COVID-19 impacts
Virtual Expert Forum with internal and external experts addressed the diagnosis, management, and prognosis of the most common lasting symptoms of COVID-19
14:10
Long-haulers and chronic fatigue
Trends in fatigue due to Secondary COVID Syndrome...
Preprint
Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
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Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem, and...
"AIC 2021, Advancements in Clinical Research and Innovative Practices in Functional Medicine, will feature preeminent researchers, clinicians, and thought leaders presenting clinical content with a focus on the resilience of patients as well as practitioners. The conference will highlight the...
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Abstract
Documenting the importance of NK cell function as a biomarker for diseases and physiologic conditions including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), will require assays amenable to clinical implementation and standardization. Research studies typically perform...
Highlights
• ME/CFS is characterized by skewed B cell receptor gene usage.
• Upregulation of specific IGHV genes correlated to infection-related episodes at onset.
• Plasmablasts of ME/CFS patients upregulated interferon response genes.
• B cell receptor repertoire analysis can provide a useful...
Abstract
Policy Points
An estimated 700,000 people in the United States have “long COVID,” that is, symptoms of COVID‐19 persisting beyond three weeks.
COVID‐19 and its long‐term sequelae are strongly influenced by social determinants such as poverty and by structural inequalities such as...
Background
Post-exertional malaise (PEM) is a defining characteristic of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) but there is insufficient research dissecting the nature of PEM from the patients’ perspective.
Methods
A PEM questionnaire administered to 150 ME/CFS patients...
Executive summary
We are seeking your views to help inform the development of the government’s Women’s Health Strategy.
This call for evidence is seeking to collect views on women’s health. It will run for a period of 12 weeks and is open to everyone aged 16 and over.
The easiest way to...
Interesting show about the aftermath of viruses on NPR station WHYY this morning.
One segment focuses on long COVID. Includes interviews with an immunologist who studies long-term impacts of viruses on the body and a physician trying to help her many patients suffering from long COVID.
Second...
Reverend Joe Haward shares his experiences of having ME and explores the challenges patients face in getting the reality of their lives with the disease heard by professionals and those in positions of power...
Abstract
Many patients with chronic fatigue syndrome (CFS) fail to derive benefit from evidence-based treatments such as cognitive–behavioural therapy (CBT) and graded exercise therapy leading to permanent disability. To discover whether a repeat prescription of modafinil might potentiate the...
Full title: Association of core body temperature and peripheral blood flow of the hands with pain intensity, pressure pain hypersensitivity, central sensitization, and fibromyalgia symptoms
Our aim was to analyse body core temperature and peripheral vascular microcirculation at skin hypothenar...
Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle...
View ORCID ProfileJoao Torrado Malato, View ORCID ProfileLuis Graca, View ORCID ProfileLuis Nacul, View ORCID ProfileEliana Mattos Lacerda, View ORCID ProfileNuno Sepulveda
Preprint
Abstract
Given the absence of a disease-specific biomarker, there are more than 20 symptoms-based case...
Quote:
"Catherine Hale spoke at It’s Our Community, a conference on social care reform. Catherine explained the high prevalence of energy limiting conditions and the psychological impact of not being believed.
I was a social care user back in the 1990s. I’ve had my chronic illness for over...
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