ace2

  1. Chandelier

    ACE2-like Catalytic Activity in Anti-SARS-CoV-2 Spike Protein Monoclonal Antibodies, 2026, Song et al.

    ACE2-like Catalytic Activity in Anti-SARS-CoV-2 Spike Protein Monoclonal Antibodies Abstract Many people are affected by difficult-to-understand clinical phenomena associated with acute SARS-CoV-2 infection and by post-acute sequelae of COVID-19 (PASC, or long COVID, LC). The mechanisms...
  2. Chandelier

    ACE2 dysregulation and lipid metabolism: Mechanistic interplay between COVID-19 and neurodegeneration, 2026, Orzeł (Orzel) et al.

    ACE2 dysregulation and lipid metabolism: Mechanistic interplay between COVID-19 and neurodegeneration Abstract Angiotensin-converting enzyme 2 (ACE2) is the primary cellular receptor of SARS-CoV-2. It is a key regulator of the renin-angiotensin system (RAS) and modulates blood pressure and...
  3. Chandelier

    Neuroinflammation, Pericyte Dysfunction, & Alzheimer’s Disease-Associated Gene Expression & Pathway Activation in the Brain of … Mice, 2026, Lawal

    Neuroinflammation, Pericyte Dysfunction, and Alzheimer’s Disease-Associated Gene Expression and Pathway Activation in the Brain of SARS-CoV-2-Infected Mice Abstract SARS-CoV-2 infection leads to extrapulmonary complications in multiple organs, including the brain, both in the short-term and...
  4. forestglip

    Influence of inflammatory and reninangiotensin system gene polymorphisms [..] on COVID-19 severity and the persistence of symptoms, 2026, Daudt-Lemos+

    Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study Objective We evaluated the influence of single-nucleotide...
  5. forestglip

    Preprint Long COVID Risk Loci Implicated from Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization, 2025, Cheng

    Preprint posted on MedRxiv, now posted with new title on SSRN, see post #4 Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVID Zhongshan Cheng Abstract Long COVID presents a significant public health challenge...
    • forestglip
    • Thread
    • abo ace2 ccr1 dpp9 foxp4 genetics gwas hla-a hla-c hla-dqa1 hla-dqb1 kctd16 long covid snp thbs3 tmprss2 twas wasf3
    • Replies: 14
    • Forum: Long Covid research
  6. SNT Gatchaman

    SARS-Cov-2 Replication in a [Blood–Brain Barrier Model] Induces Permeability & Disables [ACE2] Regulation of Bradykinin B1 Receptor, 2025, Coelho+

    SARS-Cov-2 Replication in a Blood–Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor Coelho, Sharton Vinicius Antunes; Souza, Gabriela Lisboa e; Bezerra, Bruno Braz; Lima, Luan...
  7. SNT Gatchaman

    Preprint ACE-2-like Enzymatic Activity in COVID-19 Convalescent Patients with Persistent Pulmonary Symptoms Associated with Immunoglobulin, 2025, Song et al.

    ACE-2-like Enzymatic Activity in COVID-19 Convalescent Patients with Persistent Pulmonary Symptoms Associated with Immunoglobulin Yufeng Song; Frances Mehl; Lyndsey M. Muehling; Glenda Canderan; Kyle Enfield; Jie Sun; Michael Yin; Sarah J. Ratcliffe; Jeffrey M Wilson; Alexandra Kadl; Judith A...
  8. SNT Gatchaman

    iPSC-derived human cortical organoids display profound alterations of cellular homeostasis following SARS-CoV-2 infection…, 2025, Cappelletti+

    iPSC-derived human cortical organoids display profound alterations of cellular homeostasis following SARS-CoV-2 infection and Spike protein exposure Gioia Cappelletti; Lorenzo Brambilla; Sergio Strizzi; Fiona Limanaqi; Valentina Melzi; Mafalda Rizzuti; Monica Nizzardo; Irma Saulle; Daria...
  9. forestglip

    Scent of COVID-19: [WGS] Analysis Reveals the Role of ACE2, IFI44, and NDUFAF4 in Long-Lasting Olfactory Dysfunction, 2025, Spedicati et al

    Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of ACE2, IFI44, and NDUFAF4 in Long-Lasting Olfactory Dysfunction Beatrice Spedicati, Alessandro Pecori, Maria Pina Concas, Aurora Santin, Romina Ruberto, Giuseppe Giovanni Nardone, Andrea D’Alessandro, Giancarlo Tirelli...
  10. forestglip

    Autoantibodies Targeting [GPCRs] and RAS-Related Molecules in Post-Acute COVID Vaccination Syndrome: A Retrospective [...], 2024, Mantovani et al

    Autoantibodies Targeting G-Protein-Coupled Receptors and RAS-Related Molecules in Post-Acute COVID Vaccination Syndrome: A Retrospective Case Series Study Mauro Mantovani, Paolo Bellavite, Serafino Fazio, Giuseppe Di Fede, Marco Tomasi, Daniele Belli, Elisabetta Zanolin Background/Objectives...
  11. SNT Gatchaman

    Effects of physical training on coagulation parameters, IL-6, and ACE-2 in COVID-19 survivors, 2024, Binabaji et al.

    Effects of physical training on coagulation parameters, interleukin-6, and angiotensin-converting enzyme-2 in COVID-19 survivors Binabaji, Soheila; Rahimi, Mohammad; Rajabi, Hamid; Keshavarz, Mohsen; Rahimi, Rahimeh; Ahmadi, Azam; Gahreman, Daniel COVID-19 is a highly contagious virus that uses...
  12. SNT Gatchaman

    A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection, 2024, Singh et al.

    A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection Singh, Ankita; Adam, Awadalkareem; Aditi, ; Peng, Bi-Hung; Yu, Xiaoying; Zou, Jing; Kulkarni, Vikram V.; Kan, Peter; Jiang, Wei; Shi, Pei-Yong; Samir, Parimal; Cisneros, Irma; Wang, Tian Viral variant is...
  13. SNT Gatchaman

    Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2, 2024, Grote et al.

    Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2 Grote, Karsten; Schaefer, Ann-Christin; Soufi, Muhidien; Ruppert, Volker; Linne, Uwe; Mukund Bhagwat, Aditya; Szymanski, Witold; Graumann, Johannes; Gercke, Yana; Aldudak, Sümeya...
    • SNT Gatchaman
    • Thread
    • ace2 actin amyloid atp atp6 coagulation cytoskeleton endothelial cells filamin-a hdl lipids proteomics statins
    • Replies: 0
    • Forum: Long Covid research
  14. SNT Gatchaman

    ACE-2-like enzymatic activity is associated with immunoglobulin in COVID-19 patients, 2024, Song et al.

    ACE-2-like enzymatic activity is associated with immunoglobulin in COVID-19 patients Yufeng Song; Regan Myers; Frances Mehl; Lila Murphy; Bailey Brooks; Jeffrey M. Wilson; Alexandra Kadl; Judith Woodfolk; Steven L. Zeichner Many mechanisms responsible for COVID-19 pathogenesis are...
  15. Sly Saint

    Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern, 2023

    Highlights • K18-hACE2 mice show sex-dependent responses to SARS-CoV-2 infection • Male and female mice display distinct proteomic signatures in SARS-CoV-2 infection • Inhalation of ACE2 reduces SARS-CoV-2 infection via decoy action and ERα modulation • Recombinant ACE2 inhibits Delta variant...
  16. SNT Gatchaman

    [Preprint] Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface, 2023, Lazou et al.

    Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface Maria Lazou; Jonathan R. Hutton; Arijit Chakravarty; Diane Joseph-McCarthy SARS-CoV-2, the virus that causes COVID-19, led to a global health emergency that claimed the lives of...
  17. E

    Preprint SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery, 2023, Booze et al

    SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery Abstract Adverse neurological and psychiatric outcomes, collectively termed the post-acute sequelae of SARS-CoV-2 infection (PASC), persist in adults clinically recovered from COVID-19...
  18. SNT Gatchaman

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication, 2023, Montezano et al.

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication Montezano, Augusto C.; Camargo, Livia L.; Mary, Sheon; Neves, Karla B; Rios, Francisco J; Stein, Ross; Lopes, Rheure A.; Beattie, Wendy; Thomson, Jacqueline; Herder, Vanessa; Szemiel, Agnieszka...
  19. E

    Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19, 2023, Cauchi

    Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19 Highlights A large percentage of patients with COVID-19 have neuromuscular manifestations. Loss of Drosophila ACE2 orthologues Ance or Ance3 impaired motoric...
  20. SNT Gatchaman

    Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion, 2023, Guo et al.

    Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion Guo, Yuexi; Kanamarlapudi, Venkateswarlu Coronavirus disease COVID-19, which is caused by severe acute respiratory syndrome coronavirus SARS-CoV-2, has become a worldwide pandemic in recent...
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