calcium

  1. Sly Saint

    Potential Implications of Mammalian Transient Receptor Potential Melastatin 7 in the Pathophysiology of ME/CFS, 2021, Du Preez, Staines et al

    Abstract The transient receptor potential (TRP) superfamily of ion channels is involved in the molecular mechanisms that mediate neuroimmune interactions and activities. Recent advancements in neuroimmunology have identified a role for TRP cation channels in several neuroimmune disorders...
  2. Hutan

    Calcium signalling; calcium channels

    Split thread from Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain, Md Shafiqur Rahman, et al, 2020 *** I was reading about calcium channels the other day. This reference about them is very readable and interesting. Don't be put...
  3. V

    Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain, Md Shafiqur Rahman, et al, 2020

    Abstract Background and Objectives Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable (48-54%), but its genetic architecture is unknown and candidate gene studies have produced inconsistent results...
  4. Andy

    Video, Emerge Symposium 2019: Dr Neil McGregor, An Omic Analysis of ME/CFS – an Assessment of Potential Mechanisms

    Thought his was an interesting presentation, https://mecfsconference.org.au/videos/neil-mcgregor/ As a spoiler, here is his last slide, summarising his main points
  5. Andy

    Chanzyme TRPM7 Mediates Ca2+ Influx Essential f/Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis & Macrophage Activation, 2018, Desal et al

    I think this seems to be talking about the opposite of what Griffiths University claimed to have found here, https://www.s4me.info/threads/the-courier-mail-australian-scientists-prove-cfs-is-real-and-have-discovered-a-test-for-it.1638/? Griffiths claim we don't have enough calcium going into...
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