channelopathy

  1. SNT Gatchaman

    Opinion Delayed-Onset Muscle Soreness Begins with a Transient Neural Switch, 2025, Sonkodi

    Delayed-Onset Muscle Soreness Begins with a Transient Neural Switch Sonkodi, Balázs Unaccustomed and/or strenuous eccentric contractions are known to cause delayed-onset muscle soreness. In spite of this fact, their exact cause and mechanism have been unknown for more than 120 years. The...
  2. H

    Australia: News from Griffith University, National Centre for Neuroimmunology and Emerging Diseases (NCNED)

    Edit: This thread includes several other threads merged with it. Some earlier threads on this team's work: The Courier Mail: Australian scientists prove CFS is real and have discovered a test for it Dec 2017 to Jan 2018 Don Staines and Griffith Aug 2018 Australia - Parliamentarians learn...
    • hixxy
    • Thread
    • australia channelopathy charity collaborative research conference funding griffith university marshall-gradisnik me australia me/cfs meet the scientists melastatin ncned staines trpm3
    • Replies: 49
    • Forum: News from organisations
  3. Sly Saint

    Altered TRPM7-Dependent Calcium Influx in Natural Killer Cells of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients, 2023, du Preez et al

    Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling multisystemic condition. The pathomechanism of ME/CFS remains unestablished; however, impaired natural killer (NK) cell cytotoxicity is a consistent feature of this condition. Calcium (Ca2+) is crucial for NK...
    • Sly Saint
    • Thread
    • calcium calcium channels channelopathy griffith university marshall-gradisnik nk cells trpm trpm7
    • Replies: 4
    • Forum: ME/CFS research
  4. C

    Review Channelopathies, 2014, June-Bum Kim

    Channelopathies June-Bum Kim Abstract Channelopathies are a heterogeneous group of disorders resulting from the dysfunction of ion channels located in the membranes of all cells and many cellular organelles. These include diseases of the nervous system (e.g., generalized epilepsy with...
  5. Andy

    Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of [ME/CFS], 2022, Eaton-Fitch et al

    Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious disorder of unknown aetiology. While the pathomechanism of ME/CFS remains elusive, reduced natural killer (NK) cell cytotoxic function is a consistent immunological feature. NK cell effector functions...
    • Andy
    • Thread
    • 2022 calcium calcium channels channelopathy griffith university ldn marshall-gradisnik me/cfs naltrexone natural killer cells ncned paper staines treatment trpm3
    • Replies: 7
    • Forum: ME/CFS research
  6. Hoopoe

    The symptoms of chronic fatigue syndrome are related to abnormal ion channel function (2000) Chaudhuri et al

    Journal link Sci-hub link Personal comment: episodes of paralysis or severe weakness which can be triggered by exertion, heat, cold, or occur upon awakening in the morning, and may improve with carbohydrates and electrolytes are symptom of periodic paralysis, although most people with periodic...
  7. Jenny TipsforME

    Periodic Paralysis, myotonia, channelopathy and ME

    My experiences, which I’ve discussed at length on The Other Forum, have led me to read up a bit about Periodic Paralysis. Reading more I feel like it might well have some biological connection to ME and/or POTS. The name is slightly misleading, it does involve symptoms other than paralysis...
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