children

Handgrip strength in children, adolescents, and young adults with suspected myalgic encephalomyelitis/chronic fatigue syndrome BACKGROUND Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in children, young people (CYP) lacks validated diagnostic biomarkers. Post-exertional malaise...

Functional outcomes of children after SARS-CoV-2 infection: An EHR-based cohort study Abstract Background Clinical manifestations of the post-acute sequelae of SARS-CoV-2, or long COVID, have been well-described. However, few pediatric studies explore the impact on everyday function. The...

Pediatric SARS-CoV-2 long term outcomes study: chest radiographic and computed tomography findings at baseline Abstract Background Radiologic findings associated with SARS-CoV-2 infection have been well described since its emergence. However, long-term clinical and radiologic complications...

Symptom variation up to two years post-SARS-CoV-2 infection in Children and Young People: results from the Children and young people with Long Covid (CLoCk) study Abstract Background Post Covid-19 Condition (PCC) can fluctuate over time, yet, no in-depth investigation of the heterogeneous PCC...

Beyond functional independence: symptom burden and emotional difficulties in pediatric long COVID—a cross-sectional exploratory study Abstract Background: Pediatric Long COVID poses significant challenges to daily functioning, yet its real-world impact remains poorly understood. Standard...

Long-term trajectories of social adjustment and emotional/behavioral problems in pediatric post-acute COVID-19 Abstract COVID-19 has been associated with adverse mental health outcomes in children. However, evidence regarding the long-term trajectories of post-acute symptoms remains limited...

SSRI/SNRI and long COVID in children and adolescents with neuropsychiatric conditions: a cohort study from the RECOVER Initiative Abstract Long COVID has been an important health concern in children and adolescents, yet factors associated with its development remain incompletely understood...

Novel activity and participation scales for children, adolescents, and young adults with postacute infection and vaccination syndromes and/or ME/CFS Children, adolescents, and young adults (CYP) with postacute infection and vaccination syndromes (PAIVS), and/or myalgic...

Retinal microvascular alterations consistent with endothelial dysregulation in paediatric post-COVID-19 syndrome: A prospective matched-cohort study Persistent symptoms following SARS-CoV-2 infection in children remain poorly understood, and objective biological correlates are scarce. The...

Immune-metabolic trajectories delineate subgroups in paediatric long COVID Most children and adolescents recover rapidly from SARS-CoV-2 infection, yet a subset develops paediatric long COVID (LC). How immune ontogeny shapes LC biology and heterogeneity remains unclear. We deeply phenotype a...

Biomarkers of long COVID in children and young adults: a scoping review Bettina Camara, Danilo Buonsenso Abstract Following the SARS-CoV-2 pandemic, a significant percentage of people are now experiencing long-term symptoms, despite a continuing lack of concrete documentation of physiological...

Endovascular profiles linked to neutrophil activation in children and young adults with long COVID Endovascular symptoms are among the most debilitating long COVID symptoms; however, underlying mechanisms are unclear. Children and young adults with long COVID, an understudied population, offer...

School Difficulties and Long COVID in Children and Adolescents OBJECTIVE Pediatric Long COVID (LC) is an infection-associated chronic condition following SARS-CoV-2 infection. While research has begun to elucidate clinical phenotypes, functional impacts are not well described. METHODS...

Severe acute COVID-19 and early long COVID signals in paediatric cohorts: an analysis of real-world data from two health departments, Germany BACKGROUND Severe acute coronavirus disease 2019 (COVID-19) is uncommon in children; however, its development can lead to longer-term health problems...

Microcirculatory impairment and increased arterial stiffness in pediatric Long COVID patients PURPOSE The exact pathogenesis of Long COVID remains unclear. Microvascular and endothelial dysfunction, established contributors to SARS-CoV-2-related conditions, appear to play a role in pediatric...

Now published, see post #7. Risk Factors for Severe Post-COVID Condition in Children, Adolescents, and Young Adults [Line breaks added] Background Post-COVID condition (PCC) in children and young people (PCCcyp) remains a significant health burden. Early identification of patients at risk...

Fatigue in children and young people up to 24 months after infection with SARS-CoV-2 Persistent fatigue is common following acute SARS-CoV-2 infection. Little is known about post-infection fatigue trajectories in children and young people (CYP). This paper reports on a longitudinal analysis of...

The second-order effects that the COVID-19 pandemic has had on pediatric populations INTRODUCTION SARS-CoV-2 can have long-term health consequences that persist beyond acute infection. While this is evident in adults and the elderly, the impact on children and adolescents remains under...

Persistent neurological sequelae in children and adolescents after SARS-CoV-2: a scoping review OBJECTIVES For the past five years, COVID-19 has not only been a priority for health planning but also a hotspot for clinical research. Yet, the weight of the worldwide COVID-19 pandemic arises from...

Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients using a microfluidic assay Long COVID (LC) impacts one in five children after an acute SARS-CoV-2 infection. Typical LC symptoms include fatigue, brain fog, pain, and shortness of breath, which can significantly...