cognitive dysfunction

Glymphatic system dysfunction in recovered patients with mild COVID-19: A DTI-ALPS study Lin Wu; Zhi Zhang; Xiao Liang; Yao Wang; Yuan Cao; Meng Li; Fuqing Zhou Central nervous sequelae are often reported in recovered patients with COVID-19. It is not clear whether recovered COVID-19 patients...

Association between COVID-19 and outstanding academic performance at a Spanish university Amer, Fares; López, Tamara; Gil-Conesa, Mario; Carlos, Silvia; Ariño, Arturo H; Carmona-Torre, Francisco; Martínez-González, Miguel A.; Fernandez-Montero, Alejandro SARS-CoV-2 is the causative agent of...

Abstract Debilitating symptoms of fatigue and accompanying “brain fog” are observed among patients with various chronic health conditions. Unfortunately, an efficient and psychometrically sound instrument to assess these co-occurring symptoms is unavailable. Here, we report the development and...

Abstract The present study contributes to an expanding literature investigating the systemic and structural issues that serve to disadvantage disabled academics. Individual interviews were conducted with ten female academics, each with a long-term condition impacting on energy levels and/or...

Persistent cognitive slowing in post-COVID patients: longitudinal study over 6 months Abstract Background Fatigue is a frequent and one of the most debilitating symptoms in post-COVID syndrome (PCS). Recently, we proposed that fatigue is caused by hypoactivity of the brain’s arousal network...

Prefrontal dysfunction in post-COVID-19 hyposmia: an EEG/fNIRS study Introduction: Subtle cognitive dysfunction and mental fatigue are frequent after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, characterizing the so-called long COVID-19 syndrome. This study aimed to...

Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death Background We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during...

Cognitive impairments and mental health of patients with post-COVID-19: A cross-sectional study Abstract Background Persistent cognitive complaints belong to the most frequent symptoms after COVID-19. This study explored the neuropsychological profile, mental healthand risk factors for...

Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...

Pre-print (free access) Abstract Extensive research links regular physical exercise to an overall enhancement of cognitive function across the lifespan. Here, we assess the causal evidence supporting this relationship in the healthy population, using an umbrella review of meta-analyses limited...

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome Maria Díez-Cirarda; Miguel Yus-Fuertes; Rafael Sanchez-Sanchez; Javier J. Gonzalez-Rosa; Gabriel Gonzalez-Escamilla; Lidia Gil-Martínez; Cristina Delgado-Alonso...

3 Years Into Long COVID: Where Do We Go From Here? https://www.medscape.com/viewarticle/993827 "... approximately 6% of all US adults are currently experiencing long COVID, with Hispanic/Latinx individuals, transgender individuals, and cis female individuals facing the highest rates."...

Neuropsychological deficits in patients with persistent COVID-19 symptoms: a systematic review and meta-analysis Sobrino-Relaño, Saioa; Balboa-Bandeira, Yolanda; Peña, Javier; Ibarretxe-Bilbao, Naroa; Zubiaurre-Elorza, Leire; Ojeda, Natalia Long-term persistent symptoms of COVID-19 affect...

Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome: a cross-sectional observational study Sarah Walker; Henry Goodfellow; Patra Pookarnjanamorakot; Elizabeth Murray; Julia Bindman; Ann Blandford; Katherine Bradbury; Belinda Cooper...

Full title: Cognitive functioning in postural orthostatic tachycardia syndrome among different body positions: a prospective pilot study (POTSKog study) Abstract Purpose Approximately 96% of patients with postural orthostatic tachycardia syndrome (PoTS) report cognitive complaints. We...

Now published - link here ********* Preprint Association of Baseline Cerebrovascular Reactivity and Development of Enlarged Perivascular Spaces in the Basal Ganglia Timothy J Libecap; Christopher E Bauer; Valentinos Zachariou; Colleen A Pappas; Flavius D Raslau; Peiying Liu; Hanzhang Lu; Brian...

Sylvester, R. et al. (2021) The Queen Square Brain Injury Clinic, ACNR. https://acnr.co.uk/articles/the-queen-square-brain-injury-clinic/ Abstract There is recognition of the need for rehabilitation after TBI, but less for expert diagnosis at the level of pathology and impairment during...

Neurocognitive and psychiatric symptoms following infection with COVID-19: Evidence from laboratory and population studies Hall PA, Ayaz H, Meng G, Hudson A, Sakib MN, Quah ACK, Agar TK, Lee JA, Boudreau C, Fong GT Objective: The objective of the current investigation was to examine...

Authors: Fabricia L. Fontes-Dantas et al Highlights Spike protein infusion into mouse brain induces late cognitive dysfunction Spike protein induces late hippocampal microgliosis and synapse loss Blockage of TLR4 renders mice resistant to Spike-induced cognitive dysfunction TLR4-2604G>A GG...

Every time the disability of ME/CFS is portrayed as people who were once physically active in life (often athletes) who can no longer reach the physical performance that they used to have. In severe cases, it's housebound or bedbound patients who "struggle to take a shower" or "can't go out for...