COVID-19 Infection and Subsequent Psychiatric Morbidity, Sleep Problems and Fatigue: Analysis of an English Primary Care Cohort of 226,521 Positive Patients
Abstract
Background: While some people who have had COVID-19 experience fatigue and sleep problems long after the acute phase of the...
Abstract
Introduction
COVID-19 long-haulers, also decribed as having “long-COVID” or post-acute COVID-19 syndrome, represent 10% of COVID-19 patients and remain understudied.
Methods
In this prospective study, we recruited 30 consecutive patients seeking medical help for persistent symptoms...
Abstract
Introduction
COVID-19 has caused unprecedented hardships in the 21st century with more than 150 million infections. Various immunological phenomena have been described during the course of the infection, and this infection has also triggered autoimmunity. Rheumatological illnesses have...
Introduction
Long-term COVID symptoms marked by autonomic dysfunction1 and cardiac damage2 following COVID-19 infection have been noted for up to 6 months after symptom onset,3 but to date have not been quantified, to our knowledge. Previous studies have found that wearable data can improve...
Abstract
Purpose of Review
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global health challenge. This review aims to summarize the incidence, risk factors, possible pathophysiology, and proposed management of neurological...
No idea where to put this otherwise as it's a direct consequence of the pandemic and this is preliminary data, but what it suggests is too massive to ignore, especially as it challenges long-held dogma.
(Paragraphs added for legibility)
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients who sustain an acute SARS-CoV-2 infection are developing a wide range of persistent...
Purpose: Much effort has been directed toward studying COVID-19 symptoms; however, the post–COVID-19 phase remains mysterious. The aim of this work was to conduct a clinical and neurophysiological evaluation of physical and mental fatigue in COVID-19 long-haulers and to study whether markers of...
Many COVID-19 survivors of all ages experience alarming neurological and physical signs and symptoms post-infection. Dementia-like symptoms, including memory loss and confusion—described as "brain fog"—are lingering burdens for some, while others confront an array of physical symptoms including...
As many others have pointed out, the clusters of symptoms reported by patients post-COVID-19 are not unique or specific to long COVID. Patients with similar assortments of chronic symptoms are commonly encountered in neurology, rheumatology, infectious diseases, and other subspecialty clinics...
Abstract from 2021 preprint
There is strong evidence for brain-related pathologies in COVID-19, some of which could be a consequence of viral neurotropism. The vast majority of brain imaging studies so far have focused on qualitative, gross pathology of moderate to severe cases, often carried...
Moderator note.
This post has been copied and following posts moved from this thread:
Possibility of ME or PVFS after Covid-19
Big thanks to @Andy for posting this. I posted similar on Twitter and got very lucky
It's amazing and, hopefully, this will lead to serious action by the WHO.
"In a series of definitive pieces that earned him the 2021 Pulitzer Prize for explanatory reporting, The Atlantic’s Ed Yong anticipated the course of the coronavirus pandemic, clarified its dangers, and illuminated the American government’s disastrous failure to curb it."...
Abstract
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, neurological symptoms increasingly moved into the focus of interest. In this prospective cohort study, we assessed neurological and cognitive symptoms in hospitalized coronavirus disease-19 (COVID-19)...
Performed detailed molecular and spatial analysis of the COVID-19 brain immune response
Pathognomonic microglial nodules and T cell infiltration are present in COVID-19 brains
Altered microglia-T cell interactions correlate with systemic measures of inflammation
Vascular leakage is linked with...
bioRxiv preprint: link, PDF
Summary
SARS-CoV-2 has infected over 160 million and caused more than 3 million deaths to date. Most individuals (>80%) have mild symptoms and recover in the outpatient setting, but detailed studies of immune responses have focused primarily on moderate to severe...
Text from a Solve ME email.
Bipartisan Long Hauler Legislation
Introduced Before Congress!
Thanks to your dedication and advocacy efforts, the COVID-19 Long Haulers Act (H.R. 2754) was formally introduced before Congress!
The legislation was first announced during Advocacy Week by...
Abstract
Although the accessory proteins are considered non-essential for coronavirus replication, accumulating evidences demonstrate they are critical to virus-host interaction and pathogenesis. Orf9b is a unique accessory protein of SARS-CoV-2 and SARS-CoV. It is implicated in immune evasion...
https://www.tandfonline.com/doi/full/10.1080/21641846.2021.1922140
Leonard A. Jason, Mohammed F. Islam, Karl Conroy, Joseph Cotler, Chelsea Torres, Mady Johnson & Brianna Mabie
Received 21 Apr 2021, Accepted 22 Apr 2021, Published online: 05 May 2021
Introduction
Our objective was to...
Two books have recently been published in Swedish about the covid-19 pandemic.
(I haven't yet read them, so I'm posting this only for information, not a recommendation.)
Filosofi och pandemi - Åke Gafvelin and Lapo Lappin
https://artos.se/bok/filosofi-och-pandemi/
About philosophy and the...
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