covid-19

α-synuclein Seeding Activity in the Olfactory Mucosa in COVID-19 Medical University of Innsbruck Innsbruck, Austria Estimated study completion: 2023-12-31 Brief Summary Loss of the sense of smell is a characteristic feature of COVID-19 and likely related to viral invasion of the olfactory...

Highlights • Improvement from post-COVID-19 cognitive impairment (CI) is slow • Post-COVID-19 CI is molecularly distinct from Alzheimer’s disease • Post-COVID-19 CI is associated with CSF monocyte recruitment and gene alterations • Improvement from post-COVID-19 CI is linked to greater CSF...

I don't know if Long COVID is the correct forum to put this in, since the study was about recovery from acute COVID. But I think it's possible that something that helps people recover from the acute disease could help with LC. Study

Masks and respirators for prevention of respiratory infections: a state of the science review Authors: Trisha Greenhalgh, C. Raina MacIntyre, Michael G. Baker, Shovon Bhattacharjee, Abrar A. Chughtai, David Fisman, Mohana Kunasekaran, Joe Vipond et al...

[I think this belongs here - please move if necessary] A Fight About Viruses in the Air Is Finally Over. Now It’s Time for Healthy Venting https://www.scientificamerican.com/article/a-fight-about-viruses-in-the-air-is-finally-over-now-its-time-for-healthy/

Mast cell activation triggered by SARS-CoV-2 causes inflammation in brain microvascular endothelial cells and microglia Wu, Meng-Li; Xie, Chengzuo; Li, Xin; Sun, Jing; Zhao, Jincun; Wang, Jian-Hua SARS-CoV-2-induced excessive inflammation in brain leads to damage of blood-brain barrier...

Association of COVID-19 with respiratory syncytial virus RSV infections in children aged 0–5 years in the USA in 2022: a multicentre retrospective cohort study Lindsey Wang; Pamela B Davis; Nathan Berger; David C Kaelber; Nora Volkow; Rong Xu Objective To investigate whether COVID-19 infection...

COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...

Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface Maria Lazou; Jonathan R. Hutton; Arijit Chakravarty; Diane Joseph-McCarthy SARS-CoV-2, the virus that causes COVID-19, led to a global health emergency that claimed the lives of...

Retrospective study of COVID-19 experiences in elite multinational aquatic athletes Juhász, Vencel; Csulak, Emese; Szabó, Liliána; Ocsovszky, Zsófia; Balla, Dorottya; Nagy, György; Zorzi, Alessandro; Hoepelman, Andy I. M.; Merkely, Béla; Vágó, Hajnalka; Sydó, Nóra This study assessed the...

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...

No evidence for the association between COVID-19 and neuroinflammation: A diffusion basis spectrum imaging study. Wei Zhang; Aaron J Gorelik; Qing Wang; Sara A Norton; Tamara Hershey; Janine D Bijsterbosch; Ryan Bogdan COVID continues to be a major international public health concern, the...

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection Abstract Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic1,2,3,4. Although most global efforts have focused on severe illness in COVID-19, examining asymptomatic...

New Air Monitor Can Detect COVID Virus in 5 Minutes https://www.webmd.com/covid/news/20230710/new-air-monitor-can-detect-covid-five-minutes

Generation of potentially inhibitory autoantibodies to ADAMTS13 in coronavirus disease 2019 Doevelaar, Adrian A. N.; Bachmann, Martin; Hölzer, Bodo; Seibert, Felix S.; Rohn, Benjamin J.; Zgoura, Panagiota; Witzke, Oliver; Dittmer, Ulf; Brenner, Thorsten; Paniskaki, Krystallenia; Yilmaz, Serap...

This review highlights the well-known immunomodulatory effect of mesenchymal stem cells (MSCs) as an alternative therapy for inflammatory and autoimmune diseases. Recent studies have shown that MSC-derived extracellular vesicles (EVs), including exosomes, exhibit similar therapeutic effects. The...

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity https://www.science.org/doi/10.1126/sciadv.adg2248 Abstract Numerous viruses use specialized surface molecules called fusogens to enter host cells. Many of these viruses, including the...

Access to individual patient-level data (IPD) of randomized clinical trials (RCTs) increases the reproducibility of research, facilitates exploration of effect modifiers, and leverages research investments beyond the original research question. This study aimed to describe access to IPD of RCTs...

Relationship between physical performance and perception of stress and recovery in daily life post COVID-19—An explorative study Jule Zorn; Shirin Vollrath; Lynn Matits; Martin Schönfelder; Sebastian V. W. Schulz; Achim Jerg; Jürgen M. Steinacker; Daniel A. Bizjak Introduction COVID-19 is a...

Abstract Objectives Fatigue is a pervasive clinical symptom in coronaviruses and may continue beyond the acute phase, lasting for several months or years. This systematic review and meta-analysis aimed to incorporate the current evidence for postinfection fatigue among survivors of SARS-CoV-2...