covid

Multiscale bone remodeling in COVID-19: from osteoimmune signaling to structural and mechanical impairment Jiang, G.; Buccino, F.; Vergani, L. M. Abstract The skeletal consequences of COVID-19 have emerged as an important but still underrecognized component of post-viral systemic disease...

Long-term impact of COVID-19 on haemophilia: a multicenter study in Southwest China Abstract Background The coronavirus disease 2019 (COVID-19) pandemic is not yet over as millions of people are still diagnosed with persistent symptoms of COVID-19 (long COVID) worldwide. Despite some...

Longitudinal Study of Anxiety and Depression During COVID-19 Lockdown: A Secondary Data Analysis Abstract The COVID-19 pandemic has significantly disrupted the everyday lives of people around the world, with countries announcing lockdowns aiming to reduce the spread of the virus. This...

Universal SARS-CoV-2 RT-qPCR admission screening over 21 months in a German tertiary care hospital: detection of asymptomatic infections Abstract Numerous nosocomial infections were observed in hospitals and other healthcare facilities during the COVID-19 pandemic, largely attributed to...

Neuroinflammation, Pericyte Dysfunction, and Alzheimer’s Disease-Associated Gene Expression and Pathway Activation in the Brain of SARS-CoV-2-Infected Mice Abstract SARS-CoV-2 infection leads to extrapulmonary complications in multiple organs, including the brain, both in the short-term and...

Risk of new-onset obstructive sleep apnea up to 4.5 years after COVID-19 in the urban population Abstract Obstructive sleep apnea (OSA) is linked to cardiovascular, metabolic, and cognitive morbidity. Although COVID-19 has been associated with long-term respiratory and neurological sequelae...

Spain hits back: Masks are mandatory again

The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes Published: 2022 [Line breaks added] Objectives: To evaluate the frequency and severity of new cases of youth-onset...

Autoantibodies against type I interferons are a prominent feature in SARS-CoV-2 fatal disease and hospitalization Rebeca Linhares Abreu Netto, Catherine Chen, Victor Irungu Mwangi, Carlos Eduardo Padron de Morais, Mariana Simão Xavier, Luiz Gustavo Gardinassi, Emily Marie Eriksson, Nicholas...

A highly divergent sample from a nearly extinct SARS-CoV-2 lineage in a patient with long-term COVID-19 BACKGROUND Although COVID-19 is primarily an acute disease, there are cases of persistent infection, primarily in immunocompromised patients. It is hypothesized that at least some variants...

HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes Understanding host factors driving asymptomatic versus severe disease outcomes is of key importance if we are to control emerging and re-emerging viral infections. HLA-B*15:01 has been...

The BMJ: Why scientists are rethinking the immune effects of SARS-CoV-2

Stress-induced translocation of the endoplasmic reticulum chaperone GRP78/BiP and its impact on human disease and therapy Lee; Amy S Since their discoveries in the 1960s as a family of proteins produced by cells in response to stress, molecular chaperones are increasingly recognized as major...

Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy Wu, Mike C. L.; Italiano, Ethan; Jarvis-Child, Rocko; Alwis, Imala; Smythe, Rhyll; Albornoz, Eduardo A.; Noonan, Jonathan; Portelli, Marie; Baptista, Marissa; Maclean, Jessica; Noori, Pashtana; Yang, Jinglu; Lee, John...

Abstract COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with...

Prevalence and demographics of 331 rare diseases and associated COVID-19-related mortality among 58 million individuals: a nationwide retrospective observational study Johan H Thygesen; Huayu Zhang; Hanane Issa; Jinge Wu; Tuankasfee Hama; Ana-Caterina Phiho-Gomes; Tudor Groza; Sara Khalid...

Assessment of Myocardial 18F-FDG Uptake at PET/CT in Asymptomatic SARS-CoV-2–vaccinated and Nonvaccinated Patients Authors: Takehiro Nakahara et al Published Online: Sep 19 2023 Abstract Background Patients who developed myocarditis after SARS-CoV-2 vaccination show abnormalities on cardiac...

COVID 5 years later: Learning from a pandemic many are forgetting Five years after SARS-CoV-2 surfaced, scientists reflect and look ahead to the next threat https://www.science.org/content/article/covid-5-years-later-learning-pandemic-many-are-forgetting (I added some line breaks and bolding...

SARS-CoV-2 S1 subunit produces a protracted priming of the neuroinflammatory, physiological, and behavioral responses to a remote immune challenge: A role for corticosteroids Frank; Ball; Hopkins; Kelley; Kuzma; Thompson; Fleshner; Maier Long COVID is a major public health consequence of...

Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and Multisystem Inflammatory Syndrome in Children Jacob D. Sherman; Vinit Karmali; Bhoj Kumar; Trevor W. Simon; Sarah Bechnak; Anusha Panjwani; Caroline R. Ciric; Dongli Wang; Chris Huerta; Brandi...