Pathogen and Testing Profiles in Post-Infectious Irritable Bowel Syndrome Across the COVID-19 Public Health Emergency: A Retrospective Case Series
Abstract
Background/Objectives: The COVID-19 public health emergency altered enteric infection surveillance, diagnostic testing, and antibiotic...
Genome‐Wide Association Studies of Hospitalized Influenza Identify Four Risk Loci and Reveal Shared and Unique Genetic Factors Compared With COVID‐19
ABSTRACT
Background
Influenza remains a significant global health burden, potentially leading to hospitalization and mortality. Although...
Reproducible smoker’s paradox in COVID-19 - comparative evidence from Swedish and Norwegian cohorts
Abstract
Literature on the impact of smoking on COVID-19 has been inconsistent, and the association remains incompletely understood.
To assess the effect of smoking on COVID-19 outcomes using...
Distinct CD8+ T cell types associated with COVID-19 severity in unvaccinated HLA-A2+ patients
Abstract
Despite emerging studies about coronavirus disease 2019 (COVID-19)-associated adaptive immune responses, CD8+ T cell immunity in the context of HLA restriction, particularly in unvaccinated...
Autoantibodies neutralizing type I interferons in COVID-19 patients from southern Brazil
Abstract
Inborn errors of type I IFN (IFN-I) immunity and neutralizing autoantibodies (auto-Abs) against IFN-I (AAN-I-IFNs) impair antiviral immunity and underlie critical COVID-19. Their impact on...
Non-fluorescent benzothiadiazole probe with protein-triggered turn-on fluorescence for imaging SARS-CoV-2 spike protein in biological systems
Highlights
A non-fluorescent benzothiadiazole probe becomes strongly emissive after protein ligation.
Acid-to-amide conversion yields an approximately...
Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods
Abstract
Background
We estimated vaccine effectiveness (VE) against COVID-19 and long COVID during pre-Omicron and Omicron periods, by number of doses and prior...
Viral Burden and Illness Severity During Acute SARS-CoV-2 Infection Predict Persistent Long COVID Symptoms
Abstract
Background
Long COVID is a common complication of infection with severe acute respiratory syndrome coronavirus 2, but the prevalence and predictors of the condition remain...
Localized SARS-CoV-2 Infection Triggers a Tissue-Wide Antiviral Response and Functional Impairment of Olfactory Sensory Neurons
Abstract
Olfactory dysfunction is a hallmark of COVID-19, yet the mechanisms by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes...
COVID-19 infection raises respiratory type 2 inflammatory disease risk, whereas vaccination is protective
Abstract
Background
Coronavirus disease 2019 (COVID-19) infection and vaccination have unclear impacts on type 2 inflammatory diseases. Although viral infections can drive immune...
https://www.bbc.co.uk/future/article/20260917-confusion-in-the-immune-system-how-allergies-can-develop-later-in-life
1400-word article.
Excerpt:
The Covid 'on switch'
Some people are born with a genetic predisposition to allergy. But "it's not all genetics," says Ruchi Gupta, director of...
REmotely monitored, Mobile health-supported Multidomain Rehabilitation with High Intensity Interval Training for COVID-19 (REMM-HIIT-CoV): Trial Design and Rationale
Abstract
Importance
Individuals hospitalized with COVID-19 are at increased risk for prolonged physical, cognitive, and...
Manipulation of information in times of crisis: evidence from Covid excess mortality
Karlinsky, Ariel; Shayo, Moses
Abstract
Governmental information manipulation has been hard to measure and study systematically.
This paper provides comparable country-level estimates of the extent of...
Annual vaccination with BNT162b2 in Germany can avoid substantial clinical and economic burden of COVID-19 disease
Abstract
Aims
To quantify the clinical and economic burden of Coronavirus disease 19 (COVID-19), and burden potentially avoided with annual vaccination, in German adults in an...
Persistent Vocal Alterations and Throat Clearing in Professional Singers Following COVID-19 Infection: A Cross-Sectional Study from China
Li, Yuan; Wang, Jun
Abstract
Professional singers represent a uniquely vulnerable population whose livelihoods depend on optimal vocal function, yet the...
COVID-19 Vaccine Effectiveness and Safety for the 2026-2027 Respiratory Season
Abstract
Importance SARS-CoV-2 remains a substantial cause of respiratory illness, morbidity, and mortality.
Evidence to date has demonstrated that COVID-19 vaccines reduce the risk of severe disease, including...
Risk of hepatitis B reactivation in COVID-19 patients receiving corticosteroid therapy
Abstract
COVID-19 and HBV are significant public health issues, and managing their co-infection remains unclear.
Corticosteroid therapy improves survival in severe COVID-19 but may increase the risk of HBV...
Platelet-derived serotonin drives age-related lung pathology in SARS-CoV-2 infection
Editor’s summary
The factors that drive age-related susceptibility to severe COVID-19 and related disorders like COVID-19–associated coagulopathy (CAC) are not completely understood.
Marotta et al. report...
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