cytokines

Bruce K. Patterson, Jose Guevara-Coto, Javier Mora, Edgar B. Francisco, Ram Yogendra, Rodrigo A. Mora-Rodríguez, Christopher Beaty, Gwyneth Lemaster, Gary Kaplan DO, Amiram Katz & Joseph A. Bellanti Abstract The absence of a long COVID (LC) or post-acute sequelae of COVID-19 (PASC)...

Cytokine Profile in Patients with Postacute Sequelae of COVID-19 Nathalie Ghorra; Alexandros Popotas; Tatiana Besse-Hammer; Anne Rogiers; Francis Corazza; Carole Nagant The enduring impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease manifestation, COVID-19...

Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...

Chronic fatigue syndrome and circulating cytokines: A systematic review S Blundell, KK Ray, M Buckland, PD White There has been much interest in the role of the immune system in the pathophysiology of chronic fatigue syndrome (CFS), as CFS may develop following an infection and cytokines are...

https://pubmed.ncbi.nlm.nih.gov/38808863/ Abstract Background: Over 30% of patients with COVID-19 have persistent symptoms that last beyond 30 days and referred to as Long COVID. Long COVID has been associated with a persistent elevation in peripheral cytokines including interleukin-6...

Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content Gerdle, Björn; Dahlqvist Leinhard, Olof; Lund, Eva; Lundberg, Peter; Forsgren...

Now published: Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+']link here[/URL] Preprint Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of...

Chloride Homeostasis Regulates cGAS-STING Signaling Jared Morse; Danna Wang; Serena Mei; Danielle Whitham; Colby Hladun; Costel C. Darie; Herman O Sintim; Modi Wang; KaHo Leung The cGAS-STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride...

[In mice] Introduction: Post-infection syndromes are characterised by fatigue, muscle pain, anhedonia, and cognitive impairment; mechanistic studies exploring these syndromes have focussed on pathways downstream of Toll-like receptor (TLR) 4 activation. Here, we investigated the mechanistic...

Persistent immune abnormalities discriminate post-COVID syndrome from convalescence Sbierski-Kind, Julia; Schlickeiser, Stephan; Feldmann, Svenja; Ober, Veronica; Grüner, Eva; Pleimelding, Claire; Gilberg, Leonard; Brand, Isabel; Weigl, Nikolas; Ahmed, Mohamed I. M.; Ibarra, Gerardo; Ruzicka...

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19 Deepthi Ashok; Ting Liu; Joseph Criscione; Meghana Prakash; Byunggik Kim; Julian Chow; Morgan Craney; Kyriakos Papanicolaou; Agnieszka Sidor; D. Brian Foster; Andrew Pekosz...

Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon Nikhil Sharma; Xu Qi; Patricia Kessler; Ganes C. Sen Type I interferon (IFN) is induced in virus infected cells, secreted and it inhibits viral replication in neighboring cells. IFN is also an important player in many non-viral...

Abstract Dysregulation of the kynurenine pathway (KP) is believed to play a significant role in neurodegenerative and cognitive disorders. While some evidence links the KP to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), further studies are needed to clarify the overall picture of...

Full Title: Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 with and without POTS syndrome; a multi-omic profiling study, 2023, Ali Mahdi et al Abstract Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction, especially...

COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...

Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses Maryam Nayyerabadi; Lyvia Fourcade; Swarali A. Joshi; Prabha Chandrasekaran; Arpita Chakravarti; Chantal Massé; Marie-Lorna Paul; Joanie Houle; Amina M. Boubekeur; Charlotte DuSablon...

Prolonged T-cell activation and long COVID symptoms independently associate with severe COVID-19 at 3 months Marianna Santopaolo; Michaela Gregorova; Fergus Hamilton; David Arnold; Anna Long; Aurora Lacey; Alice Halliday; Holly Baum; Kristy Hamilton; Rachel Milligan; Elizabeth Oliver; Olivia...

Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, heterogenous disease characterized by unexplained persistent fatigue and other features including cognitive impairment, myalgias, post-exertional malaise, and immune system dysfunction. Cytokines are present in...

Full title: High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 patients Background Cytokines induced by SARS-CoV-2 infection play a crucial role in the pathophysiology of COVID-19 and...

Abstract Background The role of cytokines in the pathophysiology, diagnosis, and prognosis of small fiber neuropathy (SFN) is incompletely understood. We studied expression profiles of selected pro- and anti-inflammatory cytokines in RNA from white blood cells (WBC) of patients with a medical...