cytokines

Peripheral blood cytokines during early and post-acute stages of SARS-CoV-2 infection are associated with disease severity and long-term symptoms Abstract Background: U.S. Veterans experience a high burden of COVID-19; characterizing immune responses associated with COVID-19 outcomes could...

IL-6 family cytokines behind acute COVID-19 and Long COVID syndrome: Mechanisms, biomarkers, and intervention strategies Bustos, Matilde; Rodríguez-Hernández, María Ángeles Highlights IL-6 family cytokines differentially contribute to COVID-19 and Long COVID. Biomarker strength differs among...

Evaluation of neuronal and immunological biomarkers in post-COVID-19 condition Highlights Plasma biomarkers reveal persistent inflammation in post-COVID condition (PCC) volunteers. Volunteers with neurological symptoms PCC-NS showed high IgA levels. PCC-NS volunteers presented elevated...

Microglial reactivity and neuroinflammation-driven changes in motivational behaviors are regulated by Orai1 calcium channels Abstract Microglia are the brain’s resident immune cells that respond to injury and disease by transitioning between homeostatic and reactive states. These cell state...

Abstract Post-acute sequelae of Covid-19 (PASC) refer to persistent symptoms lasting weeks to months after acute SARS-CoV-2 infection. However, identifying biological mechanisms, potential therapeutic targets, and modifiable environmental risk factors remains necessary. Here, we analyzed...

I posted in a different section about a month ago asking for a list if bloodwork, specifically cytokines, for my sister with ME and LC. I got a few responses that there are no biomarkers for ME or LC. I researched and made a list and my sister's doctor agreed to 8 of them. 5 came back abnormal...

Abstract Background: Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a debilitating condition characterized by persistent fatigue and multisystemic symptoms, such as cognitive impairment, musculoskeletal pain, and post-exertional malaise. Recently, parallels have...

Cytokine profiles associated with persisting symptoms of post-acute sequelae of COVID-19 Ji-Soo Kwon, Euijin Chang, Hyeon Mu Jang, Ji Yeun Kim, Woori Kim, Ju Yeon Son, Junho Cha, Choi Young Jang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim...

Full title: Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles Abstract While there are many postulates for the etiology of post-viral chronic fatigue and other...

https://www.mdpi.com/2227-9059/13/5/1200 Abstract Background/Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifaceted and diverse disorder with an ambiguous etiology. Recent evidence indicates that immune system impairment and inflammatory mechanisms are pivotal...

[ Embargoed PhD thesis; abstract only. ] Abstract Background: Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a disabling multisystem complex disorder with no known etiology or approved treatment. Our studies aimed to assess the link between ME/CFS and autoimmune disease (AID)...

Effects of a mild inflammatory challenge on cytokines and sickness behavior: A randomized controlled trial using the influenza vaccine Jolink; Feldman; Antenucci; Cardenas; West; Nakamura; Muscatell The influenza vaccine has reliably been associated with mild, within-person increases in...

I’ve been reading/listening to lots about the immune system, particularly B and T cells. And thought it may be worth sharing some links to info I’ve found useful. If others have useful resources please chip in! There’s a lot of sources here and duplication, I found reading/listening to...

SARS-CoV-2 Viral Load and Cytokine Dynamics Profile as Early Signatures of Long COVID Condition in Hospitalized Individuals Jacobo Alonso Domínguez; Inés Martínez Barros; Irene Viéitez; Mercedes Peleteiro; Beatriz Calderón-Cruz; José A. González-Nóvoa; Alexandre Pérez González; Virginia Leiro...

2015 study Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome Mangalathu S. Rajeevan, Irina Dimulescu, Janna Murray 1, Virginia R. Falkenberg, Elizabeth R. Unger Abstract Recent evidence suggests immune and inflammatory alterations are...

Abstract: This study aimed to identify signalling and metabolic pathways significantly impacted by alterations in cytokine and metabolic levels in response to acute cold exposure (CWI) following rest and exercise. In line with some previous studies, acute exposure to cold and exercise...

Abstract: Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness. Clarifying the way the brain processes information generated by the innate immune system is accompanied by a progressive elucidation of the cellular and...

Enhanced Gene Expression Following Vaccination in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Ekua W Brenu, Gunn M Atkinson, Mieke L van Driel, Sanne Kreijkamp-Kaspers, Don R Staines, Sonya M Marshall-Gradisnik Abstract Vaccines have been shown to cause differential expression of genes...

Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...

Abstract Evidence linking the endothelium to cardiac injury in long coronavirus disease (COVID) is well documented, but the underlying mechanisms remain unknown. Here we show that cytokines released by endothelial cells (ECs) contribute to long-COVID-associated cardiac dysfunction. Using...