dichloroacetate

  1. Sly Saint

    Article BBC: Endometriosis: How new treatment 'changed my life' 2021

    " Taking the dog for a walk is a routine task for most people. But Jessica Rafferty would often have to cut outings short due to crippling pain. She, like one in 10 women, lives with endometriosis - a condition where tissue similar to the lining of the womb grows elsewhere inside the body. It...
  2. Nixxy

    Sodium dichloroacetate

    Hello. I’m not sure what the right category was, but I wanted to share my experience with Prof Comhaire’s sodium dichloroacetate treatment. I’ve been sick since I was 16. I had an (really bad) EBV infection. A year or 5-7 after that, a hospital specializing in CFS/Fibro checked me out and...
  3. Andy

    Lactate Dehydrogenase Inhibition with Oxamate Exerts Bone Anabolic Effect, 2020, Hollenburg et al

    In mice. Paywall, https://asbmr.onlinelibrary.wiley.com/doi/abs/10.1002/jbmr.4142 Sci hub, unable to access via at time of posting.
  4. Andy

    Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence, 2020, Khaloian

    Open access, https://gut.bmj.com/content/early/2020/02/28/gutjnl-2019-319514
  5. Andy

    Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration, 2019, O'Hara et al

    Open access, https://www.frontiersin.org/articles/10.3389/fnmol.2019.00219/full
  6. Andy

    A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing [PDH] complex deficiency, 2019, Bedoyan et al

    Full title: A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing pyruvate dehydrogenase complex deficiency Open access at https://onlinelibrary.wiley.com/doi/full/10.1002/jmd2.12054
  7. Andy

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Induced by Repeated Forced Swimming in Mice, 2019, Hara et al

    More rodent torture. They may well have established chronic fatigue through over-training the mice but they haven't proven this as a mouse model for ME/CFS. Open access at https://www.jstage.jst.go.jp/article/bpb/42/7/42_b19-00009/_html/-char/en
    • Andy
    • Thread
    • 2019 dichloroacetate hara me/cfs mice paper swimming
    • Replies: 17
    • Forum: ME/CFS research
  8. D

    Ongoing ME/CFS treatment research

    Hello, I would like to hear Your opinions on Dr. Frank Comhaire's recent studies and findings. He is guessing that this nutriceutical could help improving symptoms to about 30% of people with ME/CFS. He developed a formula to predict which groups of the patients could benefit from the...
  9. Indigophoton

    Treating patients suffering from myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) with sodium dichloroacetate, Comhaire 2018

    The new paper mentioned later on in this thread, authored by Frank Comhaire, @ME/CFS, has been published, http://www.medical-hypotheses.com/article/S0306-9877(18)30105-1/fulltext
    • Indigophoton
    • Thread
    • 2018 comhaire dichloroacetate me/cfs nutriceutical paper sodium dichloroacetate treatment
    • Replies: 113
    • Forum: ME/CFS research
  10. Dolphin

    Hypothesis piece by Amy Proal, a microbiologist with ME/CFS

    (I haven't read this myself) http://microbeminded.com/2017/10/18/a-letter-to-the-mecfs-research-community-doctors-patients/
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