Identifying DNA Methylation Patterns in Post COVID-19 Condition: Insights from a One-Year Prospective Cohort Study
Abstract
The mechanisms underlying Post COVID-19 condition (PCC), with its range of long-lasting symptoms, remain unclear. This study investigates DNA methylation patterns over...
I’ve recently found the NHS Genomics Education programme website, which includes a lot of resources, but the Bitesize genomics videos such as ‘What is genomics?’ and ‘What is Bioinformatics?’ are good accessible introductions.
https://www.genomicseducation.hee.nhs.uk/education/...
Paper from 2016 by the Hanson group. I wanted to post it here because it had a large sample size (large for ME/CFS research, probably small for genetics research).
Abstract
Background: Mitochondrial dysfunction has been hypothesized to occur in Myalgic Encephalomyelitis/Chronic Fatigue...
Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures
Wenliang Wang; Manoj Hariharan; Anna Bartlett; Cesar Barragan; Rosa Castanon; Vince Rothenberg; Haili Song; Joseph Nery; Andrew Aldridge; Jordan Altshul; Mia Kenworthy; Wubin Ding; Hanqing Liu; Wei...
BBC: Thousands of children with severe developmental disorders have finally been given a diagnosis, in a study that found 60 new diseases.
Children, and their parents, had their genetic code - or DNA - analysed in the search for answers to their condition.
There are thousands of different...
I have a 23 and Me kit in my room for years. Hesitant to use it cause of privacy issues.
Was wondering are there tests that a doctor's office can run that would be similar to 23 and Me? Then I wouldn't have to be concerned about my results, how they are going to use it now or in the future...
Professor Anders Rosén and Eirini Apostolou, PhD, at Linköping University are planning a study consisting of 3 subprojects, looking at cytokines, EBV enzyme, antibodies and reactivated retro virus etc in blood and saliva samples from 200 mild, moderate and severe ME patients and 200 controls...
I just wanted to highlight a paper that came out today in Nature Genetics: Lakhani et al. (“Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes”).
In this study, they used very large health insurance claims data to compare whether...
"Genetics is a probabilistic science, and there are no genes “for” anything in particular. I have severe reservations about the utility of genetic tests that indicate one individual’s propensity for certain conditions outside of a clinical setting; if you don’t have a PhD in genetics, these...
New blog at ME/CFS Research Review
Guest blog by Professor Chris Ponting and colleagues.
Summary
A new analysis using data from UK Biobank indicates that one version of a particular gene increases the risk of ME/CFS in women. The gene codes for a transporter protein in the mitochondrial...
Although Mitochondria may very well be related to ME/CFS the article does not mention it so I chose to put it under the heading "Health News and Research unrelated to ME/CFS".
Defeating Diseases with Energy
https://mobile.nytimes.com/2018/03/15/health/genetic-mutations-diagnosis.html?referer=https://getpocket.com/recommendations
"With a database of electronic health records and DNA samples, a team of scientists has found that 3.7 percent of patients in a hospital system carried a genetic variant...
I thought this was interesting, the significant discovery of how mitochondrial DNA ends up outside the mitochondria, where it can potentially trigger autoimmune conditions.
https://medicalxpress.com/news/2018-02-dna-scientists-rogue-molecule-trigger.amp?
There is a video clip showing the...
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