Enhanced sensitivity of the peripheral cholinergic vascular response in patients with chronic fatigue syndrome
Vance A Spence; Faisel Khan; Jill J.F Belch
Patients with chronic fatigue syndrome have a variety of clinical symptoms, with associated physical, psychological, and social disability...
Post-COVID dysautonomias: what we know and mainly what we don’t know
Goldstein, David S.
Following on from the COVID-19 pandemic is another worldwide public health challenge that is referred to variously as long COVID, post-COVID syndrome or post-acute sequelae of SARS-CoV-2 infection (PASC)...
Arterial Stiffness and Oxidized LDL Independently Associated With Post-Acute Sequalae of SARS-CoV-2
Sokratis Zisis; Jared Durieux; Christian Mouchati; Nicholas Funderburg; Kate Ailstock; Mary Chong; Danielle Labbato; Grace McComsey
Objectives
COVID-19 survivors can experience lingering symptoms...
All eyes on PCS: analysis of the retinal microvasculature in patients with post-COVID syndrome—study protocol of a 1 year prospective case–control study
Kuchler, Timon; Hausinger, Renate; Braunisch, Matthias C.; Günthner, Roman; Wicklein, Rebecca; Knier, Benjamin; Bleidißel, Nathalie; Maier...
VEGF-A plasma levels are associated with impaired DLCO and radiological sequelae in long COVID patients
Background
Long COVID, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent clinical symptoms following COVID-19.
Objective
To correlate biomarkers of...
Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study
Podrug, Mario; Koren, Pjero; Dražić Maras, Edita; Podrug, Josip; Čulić, Viktor; Perissiou, Maria; Bruno, Rosa Maria; Mudnić, Ivana; Boban, Mladen; Jerončić, Ana...
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation
Timon Kuchler; Roman Günthner; Andrea Ribeiro; Renate Hausinger; Lukas Streese; Anna Wöhnl; Veronika Kesseler; Johanna Negele; Tarek Assali; Javier Carbajo-Lozoya...
Now published - link here
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Preprint
Association of Baseline Cerebrovascular Reactivity and Development of Enlarged Perivascular Spaces in the Basal Ganglia
Timothy J Libecap; Christopher E Bauer; Valentinos Zachariou; Colleen A Pappas; Flavius D Raslau; Peiying Liu; Hanzhang Lu; Brian...
Comparative Cohort Study of Post-Acute Covid-19 Infection with a Nested, Randomized Controlled Trial of Ivabradine for Those With Postural Orthostatic Tachycardia Syndrome (The COVIVA Study)
David Saunders; Thomas B Arnold; Jason M Lavendar; Daoqin Bi; Karl Alcover; Lydia D Hellwig; Sahar T...
Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion
Guo, Yuexi; Kanamarlapudi, Venkateswarlu
Coronavirus disease COVID-19, which is caused by severe acute respiratory syndrome coronavirus SARS-CoV-2, has become a worldwide pandemic in recent...
Significance
ACh-releasing choline acetyltransferase (ChAT)+ T cells promote vasodilation and regulate blood pressure in mice, but human ChAT+ T cells and the molecular mechanisms by which ChAT-expression is regulated remain undefined. In this study, we identify primary ChAT+ T cells in patients...
Cardiovascular and haematological pathology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A role for viruses
Nunes, Kell, Pretorius
ME/CFS is a debilitating chronic condition that often develops after viral or bacterial infection. Insight from the study of Long COVID/Post...
An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group
Vijay Kunadian, Alaide...
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis
Unnikrishnan M. Chandrasekharan, Zeneng Wang, Yuping Wu, W. H. Wilson Tang, Stanley L. Hazen, Sihe Wang, M. Elaine Husni
Background...
Endothelial dysfunction in ME/CFS patients
Sandvik MK, Sørland K, Leirgul E, Rekeland IG, Stavland CS, Mella O, Fluge Ø
Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study...
Endothelial dysfunction has been proposed to play a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow-mediated dilation (FMD) is recognized as an accurate clinical method to assess endothelial function. Thus, we performed a meta-analysis of the...
Long-term cardiac pathology in individuals with mild initial COVID-19 illness
Valentina O. Puntmann, Simon Martin, Anastasia Shchendrygina, Jedrzej Hoffmann, Mame Madjiguène Ka, Eleni Giokoglu, Byambasuren Vanchin, Niels Holm, Argyro Karyou, Gerald S. Laux, Christophe Arendt, Philipp De Leuw...
Abstract
Although a number of studies have demonstrated increased release of extracellular vesicles (EVs) and changes in their origin differentials after trauma, the biologic significance of EVs is not well understood. We hypothesized that EVs released after trauma/hemorrhagic shock (HS)...
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