endothelial function

Impaired Endothelial Function in Individuals With Post-Acute Sequelae of COVID-19 Effects of Combined Exercise Training Choi, Tae Gu MS; Kim, Jae Yeop MS; Seong, Joon Youp BS; Min, Ho Jeong BS; Jung, Yong Joon MS; Kim, Yun Wook MS; Cho, Min Jeong PhD; Kim, Hyun Jeong PhD; Kunutsor, Setor K...

Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius Published 16 July 2024 Abstract Myalgic...

Enhanced sensitivity of the peripheral cholinergic vascular response in patients with chronic fatigue syndrome Vance A Spence; Faisel Khan; Jill J.F Belch Patients with chronic fatigue syndrome have a variety of clinical symptoms, with associated physical, psychological, and social disability...

Does anyone know more about this study? From the description it sounds as if the change in endothelial function is seen quickly, unlike the 2-day CPET where a delay of 24 hours is required to see changes on the second test. This would make repeated EndoPET with exercise in between a superior...

Endothelial dysfunction has been proposed to play a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow-mediated dilation (FMD) is recognized as an accurate clinical method to assess endothelial function. Thus, we performed a meta-analysis of the...

Key Points VWF(Ag):ADAMTS13 ratio ≥1.5 was evident in 28% of PCS cohort 55% of patients with impaired exercise capacity had a raised VWF(Ag):ADAMTS13 ratio ≥1.5 (OR 4) Post-COVID syndrome (PCS) or Long-COVID is an increasingly recognised complication of acute SARS-CoV-2 infection...

Women are more prone to orthostatic intolerance compared to men and have a greater vasodilatory capacity. We investigated the hypothesis that women would have greater peripheral flow-mediated dilation (FMD) while in the upright posture compared to men, which could contribute to this phenomenon...

Vascular and Microvascular Dysfunction Induced by Microgravity and Its Analogs in Humans: Mechanisms and Countermeasures Nastassia Navasiolava, Ming Yuan, Ronan Murphy, Adrien Robin, Mickael Coupé, Linjie Wang, Asmaa Alameddine, Guillemette Gauquelin-Koch, Claude Gharib, Yinghui Li and...

Immunomodulation by endothelial cells — partnering up with the immune system? Jacob Amersfoort, Guy Eelen and Peter Carmeliet Blood vessel endothelial cells (ECs) have long been known to modulate inflammation by regulating immune cell trafficking, activation status and function. However...

Highlights • COVID-19 targets endothelial cells causing active endotheliitis. • In the acute phase of COVID-19, there is significant impairment of the endothelial function. • Impairment of endothelial function is proportional to COVID-19 severity. • There is a considerable progressive...

Highlights • Patients hospitalized for COVID-19 display marked impairment in endothelial function, which is persistent following recovery from the acute infection. • Red blood cells (RBCs) from patients with COVID-19 impair vascular function through mechanisms involving increased arginase 1...

Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease characterized by severe and persistent fatigue. Along with clinical studies showing endothelial dysfunction (ED) in a...

Platelets amplify endotheliopathy in COVID-19 Tessa J. Barrett, MacIntosh Cornwell, Khrystyna Myndzar, Christina C. Rolling, Yuhe Xia, Kamelia Drenkova1, Antoine Biebuyck, Alexander T. Fields, Michael Tawil, Elliot Luttrell-Williams, Eugene Yuriditsky, Grace Smith, Paolo Cotzia, Matthew D. Neal...

An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Klaus J. Wirth, Carmen Scheibenbogen and Friedemann Paul Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic...

CHRONIC FATIGUE SYNDROME (CFS) AND FIBROMYALGIA ARE VASCULAR DISEASE FREQUENTLY TRIGGERED BY PERSISTENT INTRACELLULAR INFECTIONS. The tissue hypoperfusion and cellular hypoxia that occurs in CFS is associated with dysfunctions of the cells of the vascular walls (endothelial cells and...

Posts copied from The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS...

https://www.nature.com/articles/s41598-021-89834-9 ABSTRACT Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease characterized by unexplained debilitating fatigue. Although the etiology is unknown, evidence supports immunological abnormalities, such as persistent...

Full title: Reduced endothelial function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - results from open-label cyclophosphamide intervention study Provisionally accepted https://www.frontiersin.org/articles/10.3389/fmed.2021.642710/abstract

Open access, https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.12633