I thought it'd be good to have a thread to post research about exertion's effects on the body in healthy people, since any of these might relate to why exertion is harmful in ME/CFS.
This thread acts as a list. Please go to the individual thread for each article to discuss its contents.
If you...
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with unknown etiology or effective treatments. Post-exertional malaise (PEM) is a key symptom that distinguishes ME/CFS patients. Investigating changes in the urine metabolome between ME/CFS patients...
wondering if this might be related to PEM?
The cause is as yet unknown although there are some hypotheses.
https://www.uspharmacist.com/article/exerciseinduced-headaches-prevention-management-and-treatment
this is obviously aimed at healthy people who exercise and suggests 'building up...
We patients seem to agree that the problem is usually avoiding doing too much, rather than too little. Even knowing this very well helps us little. The problem is not one of knowledge.
Some have proposed that we patients have the personality traits of being motivated and driven and that we have...
Paywall, https://journals.lww.com/acsm-msse/Abstract/9000/Elevated_Perceived_Exertion_in_People_with_Myalgic.96253.aspx
Sci hub, not available at time of posting
Recently, I walked for longer than usual. While I was still out of the house, I gradually became more symptomatic: weaker, fatigued, dizzy, etc. After eating a slice of pizza, these symptoms improved significantly despite still being on my feet and walking. I think that is an important...
European Journal of Applied Physiology:
Unexplained exertional intolerance associated with impaired systemic oxygen extraction
by Kathryn H. Melamed, Mário Santos, Rudolf K. F. Oliveira, Mariana Faria Urbina, Donna Felsenstein, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom
Abstract...
So, I'm sure many of us are familiar with the idea of establishing an activity baseline, which is where the activity that you are able to manage doesn't trigger PEM.
I would argue though that the concept of a baseline is inherently dangerous for PwME as it implies a position that can then be...
Hi folks,
This could have gone in the Pain and Inflammation sub, but I chose this sub because what I seem to be experiencing is worsening muscles issues which I think are linked to fatiguability.
My muscles are just so sore. I am now getting this slight burning pain I associate with...
This is not a study of ME/CFS at all (mods please move if it’s in the wrong place).
I’m interested because of the time factor in the study: they studied physiological effects of exertion over time (6hrs, 24hrs, 48hrs) in relation to level of exertion (defined in proportion to failure = max...
preface
Milk is good for each; Every once in a day; Bread, there's something in there; Chicken, the tastiest piece of meat; Peanut butter, who has not grown big; Exercise is healthy ...
Who has become "not big" with the above slogans?
In the meantime it is clear that many people walk around with...
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